EPO, erythropoietin, 2056

N. diseases: 646; N. variants: 11
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease HPO
CUI: C0002871
Disease: Anemia
Anemia
0.500 AlteredExpression disease BEFREE Anemia in FAP-I is associated with inappropriately low serum erythropoietin levels. 20979939 2010
CUI: C0002871
Disease: Anemia
Anemia
0.500 AlteredExpression disease BEFREE Anemia was significantly more common in the boceprevir groups than in the control group, and erythropoietin was administered in 41 to 46% of boceprevir-treated patients and 21% of controls. 21449784 2011
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease BEFREE Anemia linked to a relative deficiency of renal erythropoietin production is a significant cause of morbidity and medical expenditures in the developed world. 22611156 2012
CUI: C0002871
Disease: Anemia
Anemia
0.500 GeneticVariation disease BEFREE Anemia was the most common side effect (n = 55, 72%) requiring erythropoietin and RBV dose reduction. 25152985 2015
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease BEFREE Anemia and neutropenia were managed with Erythropoietin and Filgrastim supplementation, respectively.Only six patients discontinued therapy. 25469044 2014
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease BEFREE Anemia Evaluation and Erythropoietin Dose Requirement Among Hemodialysis Patients: a Multicenter Study. 28174354 2017
CUI: C0002871
Disease: Anemia
Anemia
0.500 GeneticVariation disease BEFREE Anemia is an important and common problem associated with chronic kidney disease (CKD), which is caused by erythropoietin deficiency, iron-restricted erythropoiesis, inflammation, hypoxia, vitamin D deficiency, hyperparathyroidism, and obesity. 28302014 2017
CUI: C0002871
Disease: Anemia
Anemia
0.500 GeneticVariation disease BEFREE Anemia is common in breast cancer patients and can be treated with blood transfusions or with recombinant erythropoietin (EPO) to stimulate red blood cell production. 28418910 2017
CUI: C0002871
Disease: Anemia
Anemia
0.500 AlteredExpression disease BEFREE Anemia resulting from the reduced expression of erythropoietin (EPO) is a common complication of patients with chronic kidney diseases (CKD). 28625716 2017
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease BEFREE Anemia is a common complication of chronic kidney disease and is mainly caused by the inability of injured kidneys to produce adequate amounts of erythropoietin. 28651951 2017
CUI: C0002871
Disease: Anemia
Anemia
0.500 AlteredExpression disease BEFREE Anemia of critical illness is resistant to exogenous erythropoietin. 28716301 2017
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease BEFREE Anaemia is the consequence of a decrease in erythropoietin production in fibrotic kidneys. 28857467 2018
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease BEFREE Anaemia is a very common problem in patients with end-stage kidney disease (ESKD) and the use of erythropoietin-stimulating agents (ESA) has revolutionised its treatment. 29178879 2017
CUI: C0002871
Disease: Anemia
Anemia
0.500 AlteredExpression disease BEFREE Anemia induced increased human erythropoietin RNA levels in liver but not kidney. 2928334 1989
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease BEFREE Anemia of chronic kidney disease (CKD) is characterized by a lack of synthesis of erythropoietin leading to reduced red blood cell (RBC) formation and aberrant iron recycling. 29659573 2018
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease BEFREE Anaemia remains highly prevalent requiring treatment with erythropoietin and transfusions. 30290796 2018
CUI: C0002871
Disease: Anemia
Anemia
0.500 GeneticVariation disease BEFREE Anaemia in TREX1 D18N mice is accompanied by increased erythropoietin (Epo), normal hepcidin levels and the TREX1 D18N mice display an inappropriate response to anaemic challenge. 30422000 2018
CUI: C0002871
Disease: Anemia
Anemia
0.500 AlteredExpression disease BEFREE Anemia was present in adenine-fed mice, while PBI-4050 blunted these effects and led to significantly higher plasma erythropoietin (EPO) levels. 31308217 2019
CUI: C0002871
Disease: Anemia
Anemia
0.500 GeneticVariation disease BEFREE Anemia is a well-known complication of advanced CKD and treatment with erythropoietin analogues (epoetin) remains a key component of management. 31477257 2019
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease CTD_human Erythropoietin restores the anemia-induced reduction in cyclophosphamide cytotoxicity in rat tumors. 11245434 2001
CUI: C0002871
Disease: Anemia
Anemia
0.500 Therapeutic disease CTD_human Erythropoietin restores the anemia-induced reduction in cyclophosphamide cytotoxicity in rat tumors. 11245434 2001
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease BEFREE Erythropoietin, in its standard role for the treatment of anemia, is often mechanistically regarded simply as increasing blood oxygen-carrying capacity and hence decreasing tumor hypoxia. 12138409 2002
CUI: C0002871
Disease: Anemia
Anemia
0.500 AlteredExpression disease BEFREE EPO, in MPMC transplanted mice, was detected up to 3 weeks (peak at 13 +/- 1 mIU/mL), and anemia of uremic mice was corrected (35.3 +/- 0.9 mIU/mL to 41.9 +/- 1.1 mIU/mL). 12753297 2003
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease BEFREE Erythropoietin (EPO) is a glycoprotein used for curing human anemia by regulating the differentiation of erythroid progenitors and the production of red blood cells. 15672835 2004