EPO, erythropoietin, 2056

N. diseases: 646; N. variants: 11
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease HPO
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease BEFREE Specific binding of erythropoietin to spleen cells infected with the anemia strain of Friend virus. 6095306 1984
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease BEFREE The binding of labeled erythropoietin (EP) to cell surface receptors and subsequent processing of the hormone within the cell was studied in erythroid cells procured from the spleens of mice infected with the anemia strain of Friend virus. 3032937 1987
CUI: C0002871
Disease: Anemia
Anemia
0.500 AlteredExpression disease BEFREE This anemia was also associated with low serum iron and normal iron stores and increased erythropoietin levels. 2486284 1989
CUI: C0002871
Disease: Anemia
Anemia
0.500 AlteredExpression disease BEFREE Anemia induced increased human erythropoietin RNA levels in liver but not kidney. 2928334 1989
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease CTD_human These results suggest that rHu Epo might be useful for the therapy of anaemia associated with anticancer chemotherapy. 2206997 1990
CUI: C0002871
Disease: Anemia
Anemia
0.500 Therapeutic disease CTD_human These findings indicate that the anaemia induced by gentamicin is due not only to a deficiency of EPO but also to an enhancement of fragility of erythrocytes in an azotaemic environment. 1982298 1990
CUI: C0002871
Disease: Anemia
Anemia
0.500 Therapeutic disease CTD_human Recombinant human erythropoietin for patients with AIDS treated with zidovudine. 2186273 1990
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease CTD_human Recombinant human erythropoietin for patients with AIDS treated with zidovudine. 2186273 1990
CUI: C0002871
Disease: Anemia
Anemia
0.500 Therapeutic disease CTD_human These results suggest that rHu Epo might be useful for the therapy of anaemia associated with anticancer chemotherapy. 2206997 1990
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease CTD_human These findings indicate that the anaemia induced by gentamicin is due not only to a deficiency of EPO but also to an enhancement of fragility of erythrocytes in an azotaemic environment. 1982298 1990
CUI: C0002871
Disease: Anemia
Anemia
0.500 Therapeutic disease CTD_human Protection of zidovudine-induced toxicity against murine erythroid progenitor cells by vitamin E. 1893952 1991
CUI: C0002871
Disease: Anemia
Anemia
0.500 AlteredExpression disease BEFREE Human erythropoietin gene expression in liver and kidney is inducible by anemia or hypoxia. 2062846 1991
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease CTD_human Protection of zidovudine-induced toxicity against murine erythroid progenitor cells by vitamin E. 1893952 1991
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease BEFREE Synthesis of erythropoietin, the primary humoral regulator of erythropoiesis, in liver and kidney is inducible by anemia or hypoxia. 1924331 1991
CUI: C0002871
Disease: Anemia
Anemia
0.500 Therapeutic disease CTD_human We compared blood pressure after three different methods of partial correction of anemia in hemodialysis patients with similar baseline hematocrits (erythropoietin n = 12, intravenous iron alone n = 10, androgens n = 9). 1516988 1992
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease CTD_human Recombinant human erythropoietin in patients with ovarian carcinoma and anaemia secondary to cisplatin and carboplatin chemotherapy: preliminary results. 1574960 1992
CUI: C0002871
Disease: Anemia
Anemia
0.500 Therapeutic disease CTD_human Recombinant human erythropoietin in patients with ovarian carcinoma and anaemia secondary to cisplatin and carboplatin chemotherapy: preliminary results. 1574960 1992
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease CTD_human We compared blood pressure after three different methods of partial correction of anemia in hemodialysis patients with similar baseline hematocrits (erythropoietin n = 12, intravenous iron alone n = 10, androgens n = 9). 1516988 1992
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease BEFREE These results suggest that impaired production of Epo may be a direct effect of HIV-1 infection possibly contributing to anemia in AIDS. 8390370 1993
CUI: C0002871
Disease: Anemia
Anemia
0.500 GeneticVariation disease BEFREE The 5'-flanking region of the human erythropoietin (Epo) gene contains a 0.14-kb sequence that is conserved in the Epo gene from mouse and located within a promoter that is activated under hypoxic conditions such as anemia. 8486613 1993
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease BEFREE Recombinant human granulocyte-macrophage colony-stimulating factor plus recombinant human erythropoietin may improve anemia in selected patients with myelodysplastic syndromes. 8237992 1993
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease CTD_human The use of recombinant human erythropoietin to prevent carboplatin-induced anemia. 8504984 1993
CUI: C0002871
Disease: Anemia
Anemia
0.500 Therapeutic disease CTD_human Clinical studies have shown recombinant human erythropoietin (r-HuEPO) to be effective in correcting the anemia of zidovudine-treated patients infected with human immunodeficiency virus with baseline serum erythropoietin levels of 500 U/L or less. 8250662 1993
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker disease CTD_human Administration of a lower Epo dose (1 U Epo) resulted in only a modest retardation of AZT-induced anemia, although, when combined with heme, there was a great improvement in recovery of erythropoiesis. 8260696 1993