Diabetic Nephropathy
|
0.600 |
Biomarker
|
disease |
BEFREE |
Patients with DN (urinary albumin [UA] >30 mg/g of creatinine) whose estimated glomerular filtration rate (eGFR) was more than 30 mL/min were selected and their plasma renin, parathyroid hormone, serum Vitamin D, serum calcium, serum creatinine, fasting blood sugar were done as baseline measurements.
|
29386413 |
2019 |
Diabetic Nephropathy
|
0.600 |
Biomarker
|
disease |
BEFREE |
Diabetic nephropathy (DN) as a cause, CKD stages, body mass index (BMI), smoking, leukocyte count, serum albumin, iron markers, calcium, and phosphorus concentration were identified as independent risk factors for anemia.
|
28049235 |
2017 |
Diabetic Nephropathy
|
0.600 |
Biomarker
|
disease |
BEFREE |
The observation suggests that changes in transglomerular albumin traffic are demonstrable prior to the onset of diabetes and diabetic nephropathy in subjects with a potential genetic predisposition to these conditions.
|
9150479 |
1997 |
Diabetic Nephropathy
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
In addition, significant positive correlations were observed between ApoA4 and blood urea nitrogen levels and between ApoA4 and creatine levels, while significant negative correlations were seen between serum protein levels and between serum albumin levels in comparisons of DM and DN samples.
|
29675916 |
2018 |
Diabetic Nephropathy
|
0.600 |
Biomarker
|
disease |
BEFREE |
The six-week low-energy extracorporeal shock wave therapy regimen decreased urinary albumin excretion as well as reduced glomerular hypertrophy and renal fibrosis in the rat model of diabetic nephropathy.
|
31354913 |
2019 |
Diabetic Nephropathy
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The outcome of interest was DKD defined by estimated glomerular filtration rate (eGFR) values <60/mL/min/1.73 m<sup>2</sup> and/or 24-h albumin excretion >30 mg. Multivariable logistic regression models were employed to estimate odds ratios (ORs) for DKD with 95% confidence intervals (CIs).
|
31162987 |
2019 |
Diabetic Nephropathy
|
0.600 |
Biomarker
|
disease |
BEFREE |
Our results showed that salidroside treatment greatly attenuates diabetic nephropathy as evidenced by decreased urinary albumin, blood urea nitrogen and serum creatinine.
|
30668374 |
2019 |
Diabetic Nephropathy
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Thus, the association between the RAGE -374 T/A homozygous AA genotype and cardiovascular disease as well as albumin excretion in type 1 diabetic patients with poor metabolic control suggests a gene-environment interaction in the development of diabetic nephropathy and cardiovascular complications.
|
12606536 |
2003 |
Diabetic Nephropathy
|
0.600 |
Biomarker
|
disease |
BEFREE |
Glycated albumin, GA:HbA<sub>1c</sub> , duration, systolic blood pressure, mean blood glucose, and retinopathy (but not HbA<sub>1c</sub> ) were identified as independent variables that predicted the presence of DN.
|
27537245 |
2017 |
Diabetic Nephropathy
|
0.600 |
Biomarker
|
disease |
BEFREE |
Diabetic nephropathy (defined as urinary albumin excretion greater than 300 mg/24 hr) was found in 7 out of 21 siblings to patients with nephropathy and 3 out of 30 siblings to normoalbuminuric patients (P less than 0.04).
|
1513092 |
1992 |
Diabetic Nephropathy
|
0.600 |
Biomarker
|
disease |
BEFREE |
Biochemical parameters, such as fasting blood glucose, creatinine, BUN in the serum, and albumin in the urine, were determined in STZ-induced DN mice after the 8th week of STZ administration.
|
30278036 |
2018 |
Diabetic Nephropathy
|
0.600 |
Biomarker
|
disease |
BEFREE |
To evaluate the associations of urinary markers (eg albumin), glomerular (eg transferrin [TRF], immunoglobulin G [IgG]), and tubular (eg α1-microglobulin [α1-MG], β2-microglobulin [β2-MG]) markers with the development of diabetic kidney disease (DKD) in type 2 diabetes patients, as assessed by estimated glomerular filtration rate (eGFR) and albuminuria.
|
28236320 |
2018 |
Diabetic Nephropathy
|
0.600 |
Biomarker
|
disease |
BEFREE |
Urinary albumin excretion is an early sign of diabetic kidney disease, affecting every third individual with diabetes.
|
30120300 |
2018 |
Diabetic Nephropathy
|
0.600 |
Biomarker
|
disease |
BEFREE |
DN(+) patients were younger, with higher body mass index, serum triglycerides, serum creatinine, and lower serum albumin than those in DN(-) patients.
|
23399816 |
2013 |
Diabetic Nephropathy
|
0.600 |
Biomarker
|
disease |
BEFREE |
The early DN rat models were induced by streptozotocin (STZ) and confirmed by contrast-enhanced ultrasound (CEUS) and 24-h urinary albumin.
|
28642201 |
2017 |
Diabetic Nephropathy
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Treatment with Gandi capsule (GDC) not only decreased the levels of urinary albumin excretion, but also increased the levels of estimated glomerular filtration rate (eGFR), indicating that it produces a renal protective effect on diabetic nephropathy.
|
31499054 |
2019 |
Diabetic Nephropathy
|
0.600 |
Biomarker
|
disease |
BEFREE |
The expression/urinary level of IL-18 is positively correlated with the progression of diabetic nephropathy and the urinary albumin excretion rate.
|
30417374 |
2019 |
Diabetic Nephropathy
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Measurements LMNA 1908C/T polymorphism (by polymerase chain reaction restriction fragment length polymorphism, PCR-RFLP); diabetic retinopathy (by standard fundus photography); diabetic nephropathy (by urinary albumin excretion rate); diabetic neuropathy (by signs, symptoms and/or nerve conduction velocity); coronary heart disease (by symptoms of typical chest pain and/or history of myocardial infarction, and ischaemic electrocardiographic alteration and/or coronary artery bypass graft surgery); cerebral vascular disease (by ultrasonography, computed tomography and/or magnetic resonance imaging).
|
16117820 |
2005 |
Diabetic Nephropathy
|
0.600 |
Biomarker
|
disease |
BEFREE |
The urinary excretion of VEGF and sFLT-1 increased at a relatively early stage in diabetic nephropathy associated with urinary albumin excretion.
|
15610240 |
2005 |
Diabetic Nephropathy
|
0.600 |
Biomarker
|
disease |
RGD |
Diet-induced renal changes in Zucker rats are ameliorated by the superoxide dismutase mimetic TEMPOL.
|
19424163 |
2009 |
Diabetic Nephropathy
|
0.600 |
Biomarker
|
disease |
BEFREE |
The abnormal secretion of albumin via urine is the characteristic feature of a diabetic nephropathy (DN) patient.
|
28962177 |
2017 |
Diabetic Nephropathy
|
0.600 |
Biomarker
|
disease |
BEFREE |
The subjects were stratified into three groups according to classification of DN by urinary albumin to creatinine ratio (ACR) and four groups by estimated glomerular filtration rate (GFR), than analyzed.
|
30452406 |
2019 |
Diabetic Nephropathy
|
0.600 |
Biomarker
|
disease |
RGD |
The amelioration of streptozotocin diabetes-induced renal damage by Wu-Ling-San (Hoelen Five Herb Formula), a traditional Chinese prescription.
|
19397971 |
2009 |
Diabetic Nephropathy
|
0.600 |
Biomarker
|
disease |
BEFREE |
Overall, this study showed that thiol-dependent changes in albumin's tertiary structure interfere with the lysosomal proteolysis of renal TBCs, inducing molecular changes associated with interstitial fibrosis and DN progression.
|
31150688 |
2019 |
Diabetic Nephropathy
|
0.600 |
AlteredExpression
|
disease |
BEFREE |
Lower serum DHA and superoxide dismutase and higher serum β2-microglobulin and 24-hour urine albumin levels were associated with clinical DN, compared to no DN and early DN.
|
29507271 |
2018 |