F3, coagulation factor III, tissue factor, 2152

N. diseases: 456; N. variants: 10
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0524851
Disease: Neurodegenerative Disorders
Neurodegenerative Disorders
0.010 Biomarker group BEFREE How to Assess Executive Functions in a Low-Educated and Multicultural Population Using a Switching Verbal Fluency Test (the TFA-93) in Neurodegenerative Diseases? 30827122 2020
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.010 Biomarker disease BEFREE Recently, we have shown that microparticles (MPs) levels derived from leukocytes (LMPs), endothelium (EMPs), neurons (NMPs) and those expressing tissue factor (TFMPs) were higher in Alzheimer's Disease (AD) patients when compared to cognitively healthy subjects. 31472398 2019
Malignant neoplasm of urinary bladder
0.010 Biomarker disease BEFREE Signal Transduction Peptide of Tissue Factor Phosphorylated at Ser258 and the Unphosphorylated STP in Urine Are Potential Biomarkers for Bladder Cancer. 30579699 2019
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
0.010 Biomarker disease BEFREE Signal Transduction Peptide of Tissue Factor Phosphorylated at Ser258 and the Unphosphorylated STP in Urine Are Potential Biomarkers for Bladder Cancer. 30579699 2019
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma
0.010 Biomarker disease BEFREE Finally, analysis of 533 RCC samples from The Cancer Genome Atlas (TCGA) indicated that the NET score and TF value are independent prognostic factors for RCC patients. 31263677 2019
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.010 Biomarker disease BEFREE Stromal TF positivity was found exclusively in ongoing inflammation.<b>Conclusion:</b> Our study provides additional support for a divergent pathogenesis in PSC-UC, with an inflammatory environment that differs from classical UC. 31774347 2019
CUI: C0013595
Disease: Eczema
Eczema
0.010 Biomarker disease BEFREE Observational studies were selected if they examined the effects of early life PUFA or R-TFA on AD (eczema, asthma, wheeze, and allergic rhinitis) or sensitization. 29341787 2019
CUI: C0014060
Disease: Encephalitis, St. Louis
Encephalitis, St. Louis
0.010 GeneticVariation disease BEFREE SLE NETs were decorated with tissue factor (TF) and interleukin-17A (IL-17A), which promoted thrombin generation and the fibrotic potential of cultured skin fibroblasts. 30563869 2019
CUI: C0020473
Disease: Hyperlipidemia
Hyperlipidemia
0.010 AlteredExpression disease BEFREE Interpretation of a decreased level of TF in patients with psoriasis is difficult because it seems to be at odds with observations among patients with other atherosclerosis risk factors such as hypertension, hyperlipidaemia, diabetes or smoking. 31616219 2019
CUI: C0020615
Disease: Hypoglycemia
Hypoglycemia
0.010 Biomarker disease BEFREE Blood samples were collected at baseline and at 0, 30, 60, 120, 240 minutes and 24 hours after hypoglycaemia and analysed for CD31<sup>+</sup> (platelet endothelial cell adhesion molecule-1), CD54<sup>+</sup> (intercellular adhesion molecule 1), CD62-E<sup>+</sup> (E-selectin), CD105<sup>+</sup> (endoglin), CD106<sup>+</sup> (vascular cell adhesion molecule 1) and CD142<sup>+</sup> (tissue factor) EMPs by flow cytometry. 30264480 2019
Childhood Acute Lymphoblastic Leukemia
0.010 AlteredExpression disease BEFREE At initial diagnosis, platelet, endothelial-derived, and tissue factor-positive microparticle levels were significantly high in children with ALL. 31090597 2019
CUI: C0023480
Disease: Leukemia, Myelomonocytic, Chronic
Leukemia, Myelomonocytic, Chronic
0.010 Biomarker disease BEFREE CMML MSC sEVs increased HD HSC procoagulant activity, suggesting a transfer of TF from the CMML TME to HD HSCs. 31221660 2019
CUI: C0023530
Disease: Leukopenia
Leukopenia
0.010 Biomarker disease BEFREE The results of our study revealed that during the first week, there were significant elevations of fibrin, tissue factor expressions, and prothrombin time (PT) coupled with neutropenia without significant changes in liver fibrosis markers such as TGF-β, α-SMA and collagen deposition. 31158377 2019
CUI: C0024143
Disease: Lupus Nephritis
Lupus Nephritis
0.010 Biomarker disease BEFREE This study evaluates the utility of urinary pro-thrombotic molecules such as tissue factor (TF), anti-thrombotic molecules such as tissue factor pathway inhibitor (TFPI), and fibrinolytic molecules such as plasmin and d-dimer as biomarkers of lupus nephritis (LN). 31319876 2019
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.010 GeneticVariation disease BEFREE In conclusion, the EVs in patients with MM carrying TF and PPL are thus capable of exerting procoagulant activity. 30640949 2019
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
0.010 AlteredExpression disease BEFREE In the present study, TF expression in neuroblastoma as well as its association with tumor stage, pathology and outcome were assessed. 31807159 2019
CUI: C0027947
Disease: Neutropenia
Neutropenia
0.010 Biomarker disease BEFREE The results of our study revealed that during the first week, there were significant elevations of fibrin, tissue factor expressions, and prothrombin time (PT) coupled with neutropenia without significant changes in liver fibrosis markers such as TGF-β, α-SMA and collagen deposition. 31158377 2019
CUI: C0032320
Disease: Pneumoperitoneum
Pneumoperitoneum
0.010 AlteredExpression disease BEFREE Prothrombin time, activated partial thromboplastin time, and thrombin time were significantly higher in group CE from 60 minutes after pneumoperitoneum to the end of pneumoperitoneum than the other 2 groups (P < .05). 31593122 2019
CUI: C0033860
Disease: Psoriasis
Psoriasis
0.010 Biomarker disease BEFREE There were significant differences in the blood concentrations of TF and TFPI in patients with psoriasis when compared to the control group. 31616219 2019
CUI: C0035078
Disease: Kidney Failure
Kidney Failure
0.010 GeneticVariation disease BEFREE This study aimed to investigate whether hemodialysis (HD) affects tissue factor (TF), tissue factor pathway inhibitor (TFPI), and polymorphonuclear elastase (PMNE) in endstage renal disease (ESRD) patients when eliminating the effects of heparin. 31555705 2019
CUI: C0085207
Disease: Gestational Diabetes
Gestational Diabetes
0.010 AlteredExpression phenotype BEFREE There was a significant increase in EGR-1 and TF levels in HuVECs isolated form GDM mother's umbilical cord and normal HuVECs treated with high glucose condition. 30767098 2019
Idiopathic Membranous Glomerulonephritis
0.010 Biomarker disease BEFREE Circulating CD14<sup>+</sup>/TF<sup>+</sup>MPs were significantly increased in IMN patients, but this achieved significance was not observed in CD41<sup>+</sup>/TF<sup>+</sup>MPs between the two groups. 30429407 2019
CUI: C0151798
Disease: Hepatic necrosis
Hepatic necrosis
0.010 GeneticVariation phenotype BEFREE After the ConA challenge, the mice showed prompt induction of intrahepatic IFN-γ and TNF-α, followed by tissue factor (TF), which aggravated the fibrin deposition and massive liver necrosis. 31626263 2019
CUI: C0206663
Disease: Neuroectodermal Tumor, Primitive
Neuroectodermal Tumor, Primitive
0.010 AlteredExpression disease BEFREE Sapanisertib suppresses TF expression and activity and reduces the growth of pNET tumors in vivo. 30472780 2019
CUI: C0206754
Disease: Neuroendocrine Tumors
Neuroendocrine Tumors
0.010 AlteredExpression group BEFREE mTOR kinase inhibition reduces tissue factor expression and growth of pancreatic neuroendocrine tumors. 30472780 2019