|
Antithrombin III Deficiency
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
BEST PRACTICE ADVICE 10: Systemic heparin infusion is recommended for symptomatic deep vein thrombosis and portal and mesenteric vein thrombosis, but there are unresolved issues regarding monitoring with both the anti-Xa assay and the partial thromboplastin time due to cirrhosis-related antithrombin deficiency (heparin cofactor).
|
30986390 |
2019 |
|
Zika Virus Infection
|
0.010 |
Biomarker
|
disease |
BEFREE |
This paper aims to determine whether ZIKV infection on HUVECs induces apoptosis and elevation of tissue factor (TF) that leads to activation of secondary hemostasis.
|
31068911 |
2019 |
|
Malignant Childhood Neoplasm
|
0.010 |
Biomarker
|
disease |
BEFREE |
In 200 individuals, from the cardiac and vascular late sequelae in long-term survivors of childhood cancer study, TG in platelet-rich plasma (PRP) and platelet-free plasma (PFP) at 1pM tissue factor was investigated.
|
30244327 |
2019 |
|
Anastomosis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
A total of 88 patients (101 fingers) following digital amputation and subsequent repair by anastomosis of both arteries and veins were randomly allocated into three groups: (1) control group (no heparin dose), (2) low-dose heparin group (10,000 IU/day), and (3) high-dose heparin group (start at 15,000 IU/day, then adjust the dose to achieve an activated partial thromboplastin time of 1.5 to 2.5 times the baseline).
|
30907817 |
2019 |
|
Hyperplastic Polyp
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
This study investigated the impact of acute running or rest followed by standardized meal consumption on MP phenotypes and TF expression.
|
30889043 |
2019 |
|
Impaired cognition
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
PMPs, LMPs and TFMPs, were associated with cognitive impairment in this population.
|
31472398 |
2019 |
|
Postoperative septic shock
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Increased mortality was independently associated with age >60 years (adjusted odds ratio [aOR] = 3.96, 95% confidence interval [CI] = 1.69-9.77), partial thromboplastin time >38 seconds (aOR = 2.66, 95% CI = 1.09-6.62), albumin <2.0 mg/dL (aOR = 2.84, 95% CI = 1.13-7.37), coagulopathy (aOR = 3.29, 95% CI = 1.24-9.19), higher anesthesia risk category (aOR = 3.08, 95% CI = 1.18, 8.59), chronic obstructive pulmonary disease (aOR = 3.46, 95% CI = 1.13-10.9), postoperative acute respiratory distress syndrome (aOR = 5.24, 95% CI = 2.04-14.4), and postoperative septic shock (aOR = 5.14, 95% CI = 1.94-14.1).
|
30929530 |
2019 |
|
proliferative nephritis unspecified
|
0.010 |
Biomarker
|
disease |
BEFREE |
Notably, TF-bearing and IL-17A-bearing NETs were abundant in discoid skin lesions and in the glomerular and tubulointerstitial compartment of proliferative nephritis biopsy specimens.
|
30563869 |
2019 |
|
Primary sclerosing cholangitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Stromal TF positivity was found exclusively in ongoing inflammation.<b>Conclusion:</b> Our study provides additional support for a divergent pathogenesis in PSC-UC, with an inflammatory environment that differs from classical UC.
|
31774347 |
2019 |
|
Ewings sarcoma-primitive neuroectodermal tumor (PNET)
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Sapanisertib suppresses TF expression and activity and reduces the growth of pNET tumors in vivo.
|
30472780 |
2019 |
|
Carcinoma of bladder
|
0.010 |
Biomarker
|
disease |
BEFREE |
Signal Transduction Peptide of Tissue Factor Phosphorylated at Ser258 and the Unphosphorylated STP in Urine Are Potential Biomarkers for Bladder Cancer.
|
30579699 |
2019 |
|
Central neuroblastoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In the present study, TF expression in neuroblastoma as well as its association with tumor stage, pathology and outcome were assessed.
|
31807159 |
2019 |
|
Posterior subcapsular cataract
|
0.010 |
Biomarker
|
disease |
BEFREE |
Stromal TF positivity was found exclusively in ongoing inflammation.<b>Conclusion:</b> Our study provides additional support for a divergent pathogenesis in PSC-UC, with an inflammatory environment that differs from classical UC.
|
31774347 |
2019 |
|
Brain Thrombus
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The physiologic relevance was supported by birefringent CC structures adjacent to monocytes (CD14), TF, and activated complement iC3b and C5b-9 in a human brain thrombus.
|
31270150 |
2019 |
|
Post lumbar puncture syndrome
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
There was one adverse event (post-lumbar puncture syndrome) in the interlaminar approach group (out of 20 procedures) and four adverse events in TFA group (out of 27 procedures) including one serious adverse event, a subarachnoid hemorrhage that required hospitalization.
|
31604650 |
2019 |
|
Mild cognitive disorder
|
0.010 |
Biomarker
|
disease |
BEFREE |
We evaluated MPs derived from platelets (PMPs), LMPs, EMPs, NMPs and TFMPs in 43 participants, of whom 12 with probable dementia due to AD, 16 with mild cognitive impairment (MCI) and 15 with no objective cognitive or functional impairment.
|
31472398 |
2019 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Analysis of apoptotic, platelet-derived, endothelial-derived, and tissue factor-positive microparticles of children with acute lymphoblastic leukemia during induction therapy.
|
31090597 |
2019 |
|
Bisphosphonate-associated osteonecrosis
|
0.010 |
Biomarker
|
disease |
BEFREE |
BON tumors grown in mice treated with sapanisertib had significantly less TF protein and cofactor activity, and were smaller compared with tumors grown in control mice.
|
30472780 |
2019 |
|
Peripheral neuropathy due to and following chemotherapy
|
0.010 |
Biomarker
|
disease |
BEFREE |
Considering that tissue factor (TF) is an endogenous coagulation factor, we hypothesize CIPN may be induced by the high expression of TF in macrophages and sciatic nerve, which induces the molecular signal related to ischemia and hypoxia.
|
31380428 |
2019 |
|
Severe periodontitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Blood from SP patients clotted significantly (P < 0.05) more rapidly and exhibited shorter partial thromboplastin times compared with HP controls.
|
31106406 |
2019 |
|
Childhood Neuroblastoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In the present study, TF expression in neuroblastoma as well as its association with tumor stage, pathology and outcome were assessed.
|
31807159 |
2019 |
|
Blushing
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
In CS-patients, a higher number of platelet- and monocyte-cMPs and of tissue factor-rich cMPs associated to worse myocardial blush grade and thrombolysis in myocardial infarction flow.
|
29544939 |
2018 |
|
Patent ductus arteriosus
|
0.010 |
Biomarker
|
disease |
BEFREE |
Recently, neutrophil extracellular traps (NETs), whereby activated neutrophils release their intracellular contents containing DNA, histones, tissue factor, high mobility group box 1 (HMGB1) and other components have been implicated in PDA and in cancer-associated thrombosis.
|
29929491 |
2018 |
|
Hemoptysis
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
Female sex, history of antiplatelet or anticoagulative drugs, prolonged activated partial thromboplastin time, subsolid nodules, cavitary nodules and long pleura-to-target distance were revealed to be independent risk factors for haemoptysis, while mPAD enlargement (> 29.5 mm) was not.
|
29063253 |
2018 |
|
Hydrocephalus
|
0.010 |
Biomarker
|
disease |
BEFREE |
Targeting of the TF system will allow developing of new therapeutic approaches to the treatment of SAH and pathologies related to CSF flow such as hydrocephalus.
|
28350198 |
2018 |