|
Fasting blood glucose measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways.
|
22885924 |
2012 |
|
Fasting blood sugar result
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways.
|
22885924 |
2012 |
|
Malignant neoplasm of lung
|
0.050 |
Biomarker
|
disease |
BEFREE |
Besides, miRNA-199 may inhibit the malignant progression of LCa by interacting with RGS17.
|
31081094 |
2019 |
|
Malignant neoplasm of lung
|
0.050 |
AlteredExpression
|
disease |
BEFREE |
Increased RGS17 expression in some prostate and lung cancers has been demonstrated to support cancer progression, while reduced expression of RGS17 can lead to development of chemotherapeutic resistance in ovarian cancer.
|
23734683 |
2013 |
|
Malignant neoplasm of lung
|
0.050 |
AlteredExpression
|
disease |
BEFREE |
Taken together, these data have provided the first evidence of miRNA regulation of RGS17 expression in lung cancer.
|
20420807 |
2010 |
|
Malignant neoplasm of lung
|
0.050 |
Biomarker
|
disease |
BEFREE |
Single nucleotide polymorphisms (SNP) on chromosomal regions 5p15.33, 6p21.33, 6q23-25/RGS17, and 15q24-25.1 were assessed for their associations with familial lung cancer.
|
20142248 |
2010 |
|
Malignant neoplasm of lung
|
0.050 |
GeneticVariation
|
disease |
BEFREE |
A region-wide scan across 6q23-25 found significant association between lung cancer susceptibility and three single nucleotide polymorphisms in the first intron of the RGS17 gene.
|
19351763 |
2009 |
|
Carcinoma of lung
|
0.040 |
Biomarker
|
disease |
BEFREE |
Besides, miRNA-199 may inhibit the malignant progression of LCa by interacting with RGS17.
|
31081094 |
2019 |
|
Primary malignant neoplasm of lung
|
0.040 |
Biomarker
|
disease |
BEFREE |
Besides, miRNA-199 may inhibit the malignant progression of LCa by interacting with RGS17.
|
31081094 |
2019 |
|
Carcinoma of lung
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
Taken together, these data have provided the first evidence of miRNA regulation of RGS17 expression in lung cancer.
|
20420807 |
2010 |
|
Carcinoma of lung
|
0.040 |
Biomarker
|
disease |
BEFREE |
Single nucleotide polymorphisms (SNP) on chromosomal regions 5p15.33, 6p21.33, 6q23-25/RGS17, and 15q24-25.1 were assessed for their associations with familial lung cancer.
|
20142248 |
2010 |
|
Primary malignant neoplasm of lung
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
Taken together, these data have provided the first evidence of miRNA regulation of RGS17 expression in lung cancer.
|
20420807 |
2010 |
|
Primary malignant neoplasm of lung
|
0.040 |
Biomarker
|
disease |
BEFREE |
Single nucleotide polymorphisms (SNP) on chromosomal regions 5p15.33, 6p21.33, 6q23-25/RGS17, and 15q24-25.1 were assessed for their associations with familial lung cancer.
|
20142248 |
2010 |
|
Carcinoma of lung
|
0.040 |
GeneticVariation
|
disease |
BEFREE |
A region-wide scan across 6q23-25 found significant association between lung cancer susceptibility and three single nucleotide polymorphisms in the first intron of the RGS17 gene.
|
19351763 |
2009 |
|
Primary malignant neoplasm of lung
|
0.040 |
GeneticVariation
|
disease |
BEFREE |
A region-wide scan across 6q23-25 found significant association between lung cancer susceptibility and three single nucleotide polymorphisms in the first intron of the RGS17 gene.
|
19351763 |
2009 |
|
Tumor Cell Invasion
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
RGS17 plays an important role in the regulation of cancer cell proliferation, migration and invasion.
|
29559347 |
2018 |
|
Tumor Cell Invasion
|
0.030 |
AlteredExpression
|
phenotype |
BEFREE |
These data suggest that RGS17 is overexpressed in colorectal carcinoma and promotes cell proliferation, migration, and invasion.
|
28337960 |
2018 |
|
Tumor Cell Invasion
|
0.030 |
Biomarker
|
phenotype |
BEFREE |
To understand the role of miRNAs in Regulator of G Protein Signaling 17 (RGS17)-induced NSCLC, we showed that miR-203 was downregulated during tumorigenesis, and inhibited the proliferation and invasion of lung cancer cells.
|
28921827 |
2017 |
|
Malignant Neoplasms
|
0.020 |
Biomarker
|
group |
BEFREE |
In searching for potential downstream targets of miR-203, a regulator of G-protein signaling 17 (RGS17) entered our sight due to its active role in a variety of malignant tumors.
|
31298318 |
2019 |
|
Malignant Neoplasms
|
0.020 |
Biomarker
|
group |
BEFREE |
RGS17 plays an important role in the regulation of cancer cell proliferation, migration and invasion.
|
29559347 |
2018 |
|
Neoplasms
|
0.020 |
Biomarker
|
group |
BEFREE |
Subsequently colony formation assays and CCK8 cell viability assay was used to test the proliferation of NPC cells, flow cytometry was used to determine the percentage of apoptotic cells, MMP kit and flow cytometry was used to measure the mitochondrial membrane potential, and a xenograft tumour model was attached to investigate the effects of RGS17 on the growth of NPC cells in vivo.
|
30464507 |
2018 |
|
Neoplasms
|
0.020 |
Biomarker
|
group |
BEFREE |
G-Protein Signaling Protein-17 (RGS17) Is Upregulated and Promotes Tumor Growth and Migration in Human Colorectal Carcinoma.
|
28337960 |
2018 |
|
Carcinogenesis
|
0.020 |
Biomarker
|
phenotype |
BEFREE |
RGS17 inhibits tumorigenesis and improves 5-fluorouracil sensitivity in nasopharyngeal carcinoma.
|
30464507 |
2018 |
|
Lung Neoplasms
|
0.020 |
AlteredExpression
|
group |
BEFREE |
RGS17 is previously shown to be over-expressed in human lung adenocarcinomas and plays an important role in lung tumor growth.
|
20420807 |
2010 |
|
Lung Neoplasms
|
0.020 |
AlteredExpression
|
group |
BEFREE |
Human lung tumor cell proliferation and tumorigenesis in nude mice are inhibited upon knockdown of RGS17 levels.
|
19351763 |
2009 |