AMY1C, amylase alpha 1C, 278

N. diseases: 63; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0233514
Disease: Abnormal behavior
Abnormal behavior
0.010 Biomarker phenotype BEFREE Physiological stress measures were assessed using diurnal salivary alpha-amylase (sAA) and salivary cortisol, nail cortisol and parasympathetic activation (PNS) by overnight heart rate variability, and body composition (body mass index, skinfold thickness) and behavior problems (using the Strengths and Difficulties Questionnaire) in 324 children aged 2-6 years of the SPLASHY study. 30270564 2018
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.010 Biomarker group BEFREE The possibility of HSGA should be considered when an adenocarcinoma producing human salivary alpha-amylase is diagnosed away from sites where major and minor salivary glands normally are found. 9258723 1997
CUI: C0152013
Disease: Adenocarcinoma of lung (disorder)
Adenocarcinoma of lung (disorder)
0.010 AlteredExpression disease BEFREE The AMY1 gene (salivary type) was exclusively and highly expressed in the salivary glands and the amylase-producing lung adenocarcinomas. 7507116 1994
CUI: C0085631
Disease: Agitation
Agitation
0.010 AlteredExpression phenotype BEFREE Results showed that CRH administration increased plasma noradrenaline and cortisol concentrations, sAA activity, heart rate, as well as self-reported side effects (i.e. flushing in the facial area, heart rate changes, giddiness, malaise and restlessness) and stress perception, while plasma adrenaline levels remained unaffected. 28472693 2017
CUI: C2607914
Disease: Allergic rhinitis (disorder)
Allergic rhinitis (disorder)
0.010 Biomarker disease BEFREE Similar sAA secretion rate was observed between the two groups (312.8 ± 124.8 (Healthy) vs. 347.9 ± 114.0 (AR) μg/min; p = 0.2444). 30579062 2019
CUI: C0003125
Disease: Anorexia Nervosa
Anorexia Nervosa
0.010 Biomarker disease BEFREE This study investigated a possible correlation between opiorphin and stress/immune biomarkers, cortisol, salivary alpha-amylase (sAA) and secretory immunoglobulin A (sIgA), in saliva of patients with restrictive-type AN. 30880537 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.050 Biomarker disease BEFREE The change of sAA after stroop test in GAD patients can predict the severity of anxiety, but subjective psychological perception can not. 31726179 2020
CUI: C0003467
Disease: Anxiety
Anxiety
0.050 Biomarker disease BEFREE <b>Methods:</b> Salivary α-amylase (sAA), galvanic skin response (GSR) and anxiety were assessed over a 2-h operating flight. 29867525 2018
CUI: C0003467
Disease: Anxiety
Anxiety
0.050 Biomarker disease BEFREE We examined physiological stress responses (cortisol and salivary alpha-amylase [sAA]), negative emotional stress responses (anxiety and self-conscious emotions), and post-task ruminative thoughts. 31497984 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.050 AlteredExpression disease BEFREE The following outcomes will be recorded: completion of dental treatment, anxiety scores at baseline and after treatment using Frankl rating behavior scale and physiological anxiety related changes will be recorded using salivary Alpha Amylase and Cortisol levels. 31464945 2019
CUI: C0003467
Disease: Anxiety
Anxiety
0.050 Biomarker disease BEFREE We examined physiological stress responses (cortisol and salivary alpha-amylase [sAA]), negative emotional stress responses (anxiety and self-conscious emotions), and post-task ruminative thoughts. 30265076 2019
CUI: C0003469
Disease: Anxiety Disorders
Anxiety Disorders
0.050 Biomarker group BEFREE The change of sAA after stroop test in GAD patients can predict the severity of anxiety, but subjective psychological perception can not. 31726179 2020
CUI: C0003469
Disease: Anxiety Disorders
Anxiety Disorders
0.050 Biomarker group BEFREE We examined physiological stress responses (cortisol and salivary alpha-amylase [sAA]), negative emotional stress responses (anxiety and self-conscious emotions), and post-task ruminative thoughts. 30265076 2019
CUI: C0003469
Disease: Anxiety Disorders
Anxiety Disorders
0.050 Biomarker group BEFREE We examined physiological stress responses (cortisol and salivary alpha-amylase [sAA]), negative emotional stress responses (anxiety and self-conscious emotions), and post-task ruminative thoughts. 31497984 2019
CUI: C0003469
Disease: Anxiety Disorders
Anxiety Disorders
0.050 AlteredExpression group BEFREE The following outcomes will be recorded: completion of dental treatment, anxiety scores at baseline and after treatment using Frankl rating behavior scale and physiological anxiety related changes will be recorded using salivary Alpha Amylase and Cortisol levels. 31464945 2019
CUI: C0003469
Disease: Anxiety Disorders
Anxiety Disorders
0.050 Biomarker group BEFREE <b>Methods:</b> Salivary α-amylase (sAA), galvanic skin response (GSR) and anxiety were assessed over a 2-h operating flight. 29867525 2018
CUI: C1279420
Disease: Anxiety neurosis (finding)
Anxiety neurosis (finding)
0.020 Biomarker disease BEFREE No mediating roles of salivary alpha-amylase and anxiety state in the cGxE effect were found. 30192917 2019
CUI: C1279420
Disease: Anxiety neurosis (finding)
Anxiety neurosis (finding)
0.020 Biomarker disease BEFREE Immediately before and after a mindfulness session, participants completed questionnaires to assess the short-term effects on mood and state anxiety and provided saliva samples to assess salivary alpha amylase (sAA) concentrations. 30395806 2019
CUI: C0700613
Disease: Anxiety state
Anxiety state
0.020 Biomarker disease BEFREE Immediately before and after a mindfulness session, participants completed questionnaires to assess the short-term effects on mood and state anxiety and provided saliva samples to assess salivary alpha amylase (sAA) concentrations. 30395806 2019
CUI: C0700613
Disease: Anxiety state
Anxiety state
0.020 Biomarker disease BEFREE No mediating roles of salivary alpha-amylase and anxiety state in the cGxE effect were found. 30192917 2019
CUI: C0860603
Disease: Anxiety symptoms
Anxiety symptoms
0.010 AlteredExpression phenotype BEFREE This study aimed to evaluate whether the salivary alpha-amylase (sAA), cortisol levels, and anxiety symptoms differ between children with and without TMD. 29019550 2017
CUI: C1510586
Disease: Autism Spectrum Disorders
Autism Spectrum Disorders
0.010 AlteredExpression disease BEFREE Not only do these results confirm the stress-reducing nature of two types of multisensory therapy, but they support the use of sAA as a potential tool for evaluating stress levels in individuals with intellectual disability and autism spectrum disorder, providing an important physiological lens that may guide strategies in clinical and non-clinical care for individuals with disabilities. 29159888 2018
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder
0.010 Biomarker disease BEFREE Salivary α-amylase as a marker of stress reduction in individuals with intellectual disability and autism in response to occupational and music therapy. 29159888 2018
CUI: C0270327
Disease: Bedwetting
Bedwetting
0.010 Biomarker disease BEFREE T&A has a favorable therapeutic effect on NE and may decrease SNA in children with OSAS. sAA might be associated with instability of ANS by OSAS and have a consistent relationship with the apnea-hypopnea index.Our studying aims had been met. 27876406 2017
CUI: C0236734
Disease: Caffeine related disorders
Caffeine related disorders
0.010 Biomarker group BEFREE In this follow-up article, the effects of strategic caffeine administration on the previously reported diurnal profiles of sAA and performance, and the association between sAA and neurobehavioural performance were investigated. 29402402 2019