|
Obesity
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
(Cell Host Microbe 2019;25;553-564.E7) reported that AMY1 copy number, associated with obesity, also impacts microbiome composition and function.
|
31056302 |
2019 |
|
Obesity
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Recently studies have shown that the copy number of AMY1 is associated with obesity; however, the data varies with location.
|
31248128 |
2019 |
|
Obesity
|
0.100 |
Biomarker
|
disease |
BEFREE |
The results suggest that high AMY1 gene copy number protects against obesity in Portuguese young adults.
|
30200782 |
2018 |
|
Obesity
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Copy number variation (CNV) of AMY1 has been implicated in human dietary adaptation, and in population association with obesity, but neither of these findings has been independently replicated.
|
28101908 |
2017 |
|
Obesity
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Yet, we also found a significant negative contribution of AMY1 activity at baseline to the change in BMI during the 9-year follow-up, and a significant contribution of AMY1A copy number to lower obesity risk in children, suggesting a bidirectional relationship between AMY1 activity and adiposity.
|
28228143 |
2017 |
|
Obesity
|
0.100 |
Biomarker
|
disease |
BEFREE |
To further our understanding of this relationship, we: 1) examined the role of priming on physiological measures (e.g. salivary alpha amylase and skin conductance) in 70 college students by introducing positive and negative media images of individuals with obesity, and 2) assessed psychological measures (e.g. perceived stress, need to belong, and self-esteem, and Body Mass Index).
|
29084240 |
2017 |
|
Obesity
|
0.100 |
Biomarker
|
disease |
BEFREE |
In two further case-control cohorts (n = 932 and 145, for Chinese and Malays, respectively), we did not observe the previously reported association between AMY1 and obesity or body mass index.
|
27068483 |
2016 |
|
Obesity
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Recently, the highly polymorphic CNV in the salivary amylase (AMY1) gene, encoding an enzyme implicated in the first step of starch digestion, has been associated with obesity in adults and children.
|
27149670 |
2016 |
|
Obesity
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Obesity, starch digestion and amylase: association between copy number variants at human salivary (AMY1) and pancreatic (AMY2) amylase genes.
|
25788522 |
2015 |
|
Obesity
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The global association between AMY1 copy number and reduced risk of obesity seemed to be mostly driven by the contribution of the highest AMY1 copy number.
|
25394825 |
2015 |
|
Obesity
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Low Copy Number of the AMY1 Locus Is Associated with Early-Onset Female Obesity in Finland.
|
26132294 |
2015 |
|
Obesity
|
0.100 |
Biomarker
|
disease |
BEFREE |
Copy number of AMY1 is reported to be the largest genomic influence on obesity, although genome-wide association studies for obesity have found this locus unremarkable.
|
26098870 |
2015 |
|
Obesity
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The OR value of 1.19 per copy of AMY1 translates into about an eightfold difference in risk of obesity between subjects in the top (copy number > 9) and bottom (copy number < 4) 10% of the copy number distribution.
|
24686848 |
2014 |
|
Anxiety
|
0.050 |
Biomarker
|
disease |
BEFREE |
The change of sAA after stroop test in GAD patients can predict the severity of anxiety, but subjective psychological perception can not.
|
31726179 |
2020 |
|
Anxiety Disorders
|
0.050 |
Biomarker
|
group |
BEFREE |
The change of sAA after stroop test in GAD patients can predict the severity of anxiety, but subjective psychological perception can not.
|
31726179 |
2020 |
|
Anxiety
|
0.050 |
Biomarker
|
disease |
BEFREE |
We examined physiological stress responses (cortisol and salivary alpha-amylase [sAA]), negative emotional stress responses (anxiety and self-conscious emotions), and post-task ruminative thoughts.
|
31497984 |
2019 |
|
Anxiety
|
0.050 |
AlteredExpression
|
disease |
BEFREE |
The following outcomes will be recorded: completion of dental treatment, anxiety scores at baseline and after treatment using Frankl rating behavior scale and physiological anxiety related changes will be recorded using salivary Alpha Amylase and Cortisol levels.
|
31464945 |
2019 |
|
Anxiety
|
0.050 |
Biomarker
|
disease |
BEFREE |
We examined physiological stress responses (cortisol and salivary alpha-amylase [sAA]), negative emotional stress responses (anxiety and self-conscious emotions), and post-task ruminative thoughts.
|
30265076 |
2019 |
|
Anxiety Disorders
|
0.050 |
Biomarker
|
group |
BEFREE |
We examined physiological stress responses (cortisol and salivary alpha-amylase [sAA]), negative emotional stress responses (anxiety and self-conscious emotions), and post-task ruminative thoughts.
|
30265076 |
2019 |
|
Anxiety Disorders
|
0.050 |
Biomarker
|
group |
BEFREE |
We examined physiological stress responses (cortisol and salivary alpha-amylase [sAA]), negative emotional stress responses (anxiety and self-conscious emotions), and post-task ruminative thoughts.
|
31497984 |
2019 |
|
Anxiety Disorders
|
0.050 |
AlteredExpression
|
group |
BEFREE |
The following outcomes will be recorded: completion of dental treatment, anxiety scores at baseline and after treatment using Frankl rating behavior scale and physiological anxiety related changes will be recorded using salivary Alpha Amylase and Cortisol levels.
|
31464945 |
2019 |
|
Anxiety
|
0.050 |
Biomarker
|
disease |
BEFREE |
<b>Methods:</b> Salivary α-amylase (sAA), galvanic skin response (GSR) and anxiety were assessed over a 2-h operating flight.
|
29867525 |
2018 |
|
Anxiety Disorders
|
0.050 |
Biomarker
|
group |
BEFREE |
<b>Methods:</b> Salivary α-amylase (sAA), galvanic skin response (GSR) and anxiety were assessed over a 2-h operating flight.
|
29867525 |
2018 |
|
Malignant Neoplasms
|
0.030 |
Biomarker
|
group |
BEFREE |
We identified a panel of three protein biomarkers, salivary alpha amylase (AMY1), Flt3 ligand (FLT3L), and monocyte chemotactic protein 1 (MCP1), which are upregulated in human patients receiving fractionated doses of total body irradiation (TBI) therapy as a treatment for cancer.
|
30605362 |
2020 |
|
Primary malignant neoplasm
|
0.030 |
Biomarker
|
group |
BEFREE |
We identified a panel of three protein biomarkers, salivary alpha amylase (AMY1), Flt3 ligand (FLT3L), and monocyte chemotactic protein 1 (MCP1), which are upregulated in human patients receiving fractionated doses of total body irradiation (TBI) therapy as a treatment for cancer.
|
30605362 |
2020 |