|
Schizophrenia
|
0.700 |
GeneticVariation
|
disease |
BEFREE |
Differential expression and parent-of-origin effect of the 5-HT2A receptor gene C102T polymorphism: analysis of suicidality in schizophrenia and bipolar disorder.
|
17221840 |
2007 |
|
Schizophrenia
|
0.700 |
AlteredExpression
|
disease |
BEFREE |
Progressive reductions of subcortical 5-HT(2A)R density could provide an indicator of illness activity and help to predict imminent conversion to schizophrenia.
|
17899021 |
2008 |
|
Schizophrenia
|
0.700 |
Biomarker
|
disease |
BEFREE |
Our results do not, therefore, support the hypothesis that the serotonin receptor 2A gene is a liability factor for the symptomatology of schizophrenia as defined by the OPCRIT checklist.Am.J. Med.Genet.(Neuropsychiatr.Genet.)96:84-87, 2000.
|
10686558 |
2000 |
|
Schizophrenia
|
0.700 |
GeneticVariation
|
disease |
BEFREE |
We detected nominal significant association with schizophrenia for several haplotype tag SNPs (htSNPs) at HTR2A, although the significance was lost after multiple test corrections.
|
17125970 |
2007 |
|
Schizophrenia
|
0.700 |
Biomarker
|
disease |
BEFREE |
The putative role of epigenetic factors is shown by the epigenetic interpretation of genetic association studies of the genes for serotonin 2A (HTR2A) and the dopamine D3 (DRD3) receptors in schizophrenia.
|
10869881 |
2000 |
|
Schizophrenia
|
0.700 |
GeneticVariation
|
disease |
BEFREE |
We looked for an association between schizophrenia and this variant of the 5-HT2a-receptor gene in a large multicentre study.
|
8622505 |
1996 |
|
Schizophrenia
|
0.700 |
GeneticVariation
|
disease |
BEFREE |
The results suggest that the C516T polymorphism of the 5-HT2A receptor gene is not related to the susceptibility for schizophrenia in our Brazilian sample.
|
17420819 |
2007 |
|
Schizophrenia
|
0.700 |
GeneticVariation
|
disease |
BEFREE |
(2) We examined the association of three polymorphisms in the 5-HT2A receptor gene (HTR2A) with TD susceptibility--T102C(3) and his452tyr(4) in the coding region and A-1438G(5) in the promoter--in matched schizophrenia patients with (n = 59, SCZ-TD-Y) and without TD (n = 62, SCZ-TD-N) and normal control subjects (n = 96).
|
11317227 |
2001 |
|
Schizophrenia
|
0.700 |
GeneticVariation
|
disease |
LHGDN |
These data did not provide evidence for a contribution of the 102T/C SNP of HTR2A gene to susceptibility to the southern Han Chinese schizophrenia.
|
15048642 |
2004 |
|
Schizophrenia
|
0.700 |
GeneticVariation
|
disease |
BEFREE |
This study investigated whether the efficacy of aripiprazole can be predicted by functional HTR2A A-1438G/rs6313" genes_norm="3356;54187;6302">T102C polymorphisms (rs63311/rs6313) as modified by clinical factors in Han Chinese hospitalized patients with acutely exacerbated schizophrenia.
|
19387614 |
2009 |
|
Schizophrenia
|
0.700 |
GeneticVariation
|
disease |
BEFREE |
The results suggest that the human HTR2 MspI polymorphism might not be associated with a risk factor for developing alcohol dependence or susceptibility to schizophrenia.
|
10754425 |
2000 |
|
Schizophrenia
|
0.700 |
GeneticVariation
|
disease |
BEFREE |
Our findings may help to improve the understanding of the relationship between 5-HT2A and DRD3 genotypes and schizophrenia pathogenesis.
|
31813806 |
2019 |
|
Schizophrenia
|
0.700 |
Biomarker
|
disease |
HPO |
|
|
|
|
Schizophrenia
|
0.700 |
GeneticVariation
|
disease |
BEFREE |
Could HTR2A T102C and DRD3 Ser9Gly predict clinical improvement in patients with acutely exacerbated schizophrenia? Results from treatment responses to risperidone in a naturalistic setting.
|
17924589 |
2008 |
|
Schizophrenia
|
0.700 |
GeneticVariation
|
disease |
BEFREE |
To use a hierarchical approach to determine the functional effects of this single-nucleotide polymorphism on 5-HT2AR messenger RNA and protein expression, on prefrontal phenotypes linked with genetic risk for schizophrenia, and on treatment with olanzapine.
|
23842608 |
2013 |
|
Schizophrenia
|
0.700 |
GeneticVariation
|
disease |
LHGDN |
Association between the 102T/C polymorphism of serotonin-2A receptor gene and schizophrenia among south Indians.
|
12140776 |
2002 |
|
Schizophrenia
|
0.700 |
GeneticVariation
|
disease |
BEFREE |
The impact of HTR2C and HTR2A polymorphisms on body mass index (BMI), glucose-insulin homeostasis, and blood lipid levels was evaluated in 46 patients with schizophrenia or schizoaffective disorder and treated with olanzapine (n = 28) or clozapine (n = 18) for at least 6 months.
|
19142110 |
2009 |
|
Schizophrenia
|
0.700 |
GeneticVariation
|
disease |
BEFREE |
Analysis of the 5'-flanking promoter region of the 5-HT2A receptor gene in schizophrenia.
|
9326752 |
1997 |
|
Schizophrenia
|
0.700 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to investigate whether single nucleotide polymorphisms (SNPs) in DRD2 and 5-HT2 receptor genes are associated with schizophrenia in North Indian population.
|
30389402 |
2019 |
|
Schizophrenia
|
0.700 |
GeneticVariation
|
disease |
BEFREE |
These data did not provide evidence for a contribution of the 102T/C SNP of HTR2A gene to susceptibility to the southern Han Chinese schizophrenia.
|
15048642 |
2004 |
|
Schizophrenia
|
0.700 |
Biomarker
|
disease |
BEFREE |
Variants at the gene encoding for the 5-hydrosytryptamine (serotonin) receptor 2A (HTR2A) have been associated with many psychiatric disorders such as schizophrenia, mood disorders, attention deficit hyperactivity disorder, suicide, anxiety disorders, obsessive-compulsive disorder, eating disorders, and Alzheimer's disease.
|
17691947 |
2007 |
|
Schizophrenia
|
0.700 |
GeneticVariation
|
disease |
LHGDN |
Association of a serotonin receptor 2A gene polymorphism with cognitive functions in patients with schizophrenia.
|
17221846 |
2007 |
|
Schizophrenia
|
0.700 |
Biomarker
|
disease |
BEFREE |
In addition, no interactions of GRM2 and HTR2A were found in methamphetamine-induced psychosis or schizophrenia.
|
20211215 |
2010 |
|
Schizophrenia
|
0.700 |
GeneticVariation
|
disease |
BEFREE |
This finding suggests that genetic predisposition to schizophrenia may be affected by a functional 5-HT2A receptor variant that is in linkage disequilibrium with 102T/C.
|
8655141 |
1996 |
|
Schizophrenia
|
0.700 |
AlteredExpression
|
disease |
BEFREE |
Several aspects of 5-HT(2A)R expression were altered in schizophrenia.
|
11574947 |
2001 |