IGF1, insulin like growth factor 1, 3479

N. diseases: 1206; N. variants: 36
Disease: Childhood Osteosarcoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1332986
Disease: Childhood Osteosarcoma
Childhood Osteosarcoma 		0.100 PosttranslationalModification disease BEFREE p53 regulates insulin-like growth factor-I (IGF-I) receptor expression and IGF-I-induced tyrosine phosphorylation in an osteosarcoma cell line: interaction between p53 and Sp1. 9492043 1998
CUI: C1332986
Disease: Childhood Osteosarcoma
Childhood Osteosarcoma 		0.100 Biomarker disease BEFREE Evidence for modulation of osteocalcin containing gamma-carboxyglutamic acid residues synthesis by insulin-like growth factor-I and vitamin K2 in human osteosarcoma cell line MG-63. 9578515 1998
CUI: C1332986
Disease: Childhood Osteosarcoma
Childhood Osteosarcoma 		0.100 AlteredExpression disease BEFREE However, neither Ea nor Eb IGF-I mRNA could be detected under basal conditions or after stimulation with growth hormone in normal hOB cells and two human osteosarcoma cell lines with osteoblastic properties, SaOS-2 and MG-63. 8123049 1994
CUI: C1332986
Disease: Childhood Osteosarcoma
Childhood Osteosarcoma 		0.100 AlteredExpression disease BEFREE Insulin-like growth factor-I induces cyclin-D1 expression in MG63 human osteosarcoma cells in vitro. 8052269 1994
CUI: C1332986
Disease: Childhood Osteosarcoma
Childhood Osteosarcoma 		0.100 Biomarker disease BEFREE Insulin-like growth factor-I may regulate osteosarcoma and the Ewing's family of tumors (primitive neuroectodermal tumors). 8054516 1994
CUI: C1332986
Disease: Childhood Osteosarcoma
Childhood Osteosarcoma 		0.100 Biomarker disease BEFREE Insulin-like growth factor-1 modulates steroid hormone effects on osteocalcin synthesis in human MG-63 osteosarcoma cells. 8281940 1993