Allergic Reaction
|
0.400 |
GeneticVariation
|
phenotype |
GWASDB |
A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci.
|
23817569 |
2013 |
Allergic Reaction
|
0.400 |
Biomarker
|
phenotype |
CTD_human |
Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORγt cells in allergic inflammation, local lung distribution and chemokine gene expression.
|
21625544 |
2011 |
Endometriosis
|
0.340 |
Biomarker
|
disease |
CTD_human |
Molecular evidence for differences in endometrium in severe versus mild endometriosis.
|
21063030 |
2011 |
Endometriosis
|
0.340 |
Biomarker
|
disease |
CTD_human |
Unique transcriptome, pathways, and networks in the human endometrial fibroblast response to progesterone in endometriosis.
|
20864642 |
2011 |
Endometriosis
|
0.340 |
AlteredExpression
|
disease |
LHGDN |
The decrease in IL1R2 mRNA levels in eutopic endometrial tissue of endometriosis women, and the concomitant increase in IL1R1 mRNA levels in ectopic implants, reveal a profound defect in IL1R 1 and IL1R2 gene expression which may accentuate the capability of this tissue to respond to IL1 and favor its ectopic growth.
|
17517439 |
2008 |
Endometriosis
|
0.340 |
AlteredExpression
|
disease |
BEFREE |
The decrease in IL1R2 mRNA levels in eutopic endometrial tissue of endometriosis women, and the concomitant increase in IL1R1 mRNA levels in ectopic implants, reveal a profound defect in IL1R 1 and IL1R2 gene expression which may accentuate the capability of this tissue to respond to IL1 and favor its ectopic growth.
|
17517439 |
2008 |
Endometriosis
|
0.340 |
AlteredExpression
|
disease |
BEFREE |
Our study showed an imbalance in the expression of IL1R1 and IL1R2 in eutopic, and particularly in ectopic, endometrial tissues of women with endometriosis.
|
17324958 |
2007 |
Endometriosis
|
0.340 |
AlteredExpression
|
disease |
LHGDN |
Actually, a decreased IL1R2 expression is predominant in the eutopic and ectopic endometrium of women with endometriosis when compared with normal women, whereas a concomitant increase in IL1R1 expression occurs in ectopic endometrial tissue in comparison to eutopic endometrial tissue of normal or endometriotic women, particularly in the initial and most active implants.
|
17324958 |
2007 |
Endometriosis
|
0.340 |
GeneticVariation
|
disease |
LHGDN |
Polymorphisms in exons 1B and 1C of the type I interleukin-1 receptor gene in patients with endometriosis.
|
16911713 |
2006 |
Endometriosis
|
0.340 |
AlteredExpression
|
disease |
LHGDN |
Down-regulation of interleukin-1 receptor type 1 expression causes the dysregulated expression of CXC chemokines in endometriotic stromal cells: a possible mechanism for the altered immunological functions in endometriosis.
|
15472211 |
2004 |
Endometriosis
|
0.340 |
AlteredExpression
|
disease |
BEFREE |
Down-regulation of interleukin-1 receptor type 1 expression causes the dysregulated expression of CXC chemokines in endometriotic stromal cells: a possible mechanism for the altered immunological functions in endometriosis.
|
15472211 |
2004 |
Alcoholic Intoxication, Chronic
|
0.320 |
GeneticVariation
|
disease |
BEFREE |
The present study analyzed potential relationships between alcoholism or alcoholic liver disease (ALD) and IL12B 2124 G>T (rs1368439), IL16 5000 C>T (rs1131445), IL1R1 3114 C>T (rs3917328), and NFKB1 3400 A>G (rs4648143) polymorphisms.
|
29566963 |
2018 |
Alcoholic Intoxication, Chronic
|
0.320 |
GeneticVariation
|
disease |
BEFREE |
We did not find any association of alcoholism or ALD with polymorphisms in the IL1A and IL1R1 genes.
|
15797878 |
2005 |
Pneumonitis
|
0.310 |
Biomarker
|
disease |
BEFREE |
Circulating biomarker analyses demonstrated increases in CXCR2, IL1ra and IL2ra that coincided with the development of symptomatic pneumonitis.
|
31014385 |
2019 |
Pneumonitis
|
0.310 |
Biomarker
|
disease |
CTD_human |
Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORγt cells in allergic inflammation, local lung distribution and chemokine gene expression.
|
21625544 |
2011 |
Dermatologic disorders
|
0.300 |
Biomarker
|
group |
CTD_human |
Toxicogenomic analysis of chlorine vapor-induced porcine skin injury.
|
22533443 |
2012 |
Hypersensitivity
|
0.300 |
Biomarker
|
group |
CTD_human |
Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORγt cells in allergic inflammation, local lung distribution and chemokine gene expression.
|
21625544 |
2011 |
Pneumonia
|
0.300 |
Biomarker
|
disease |
CTD_human |
Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORγt cells in allergic inflammation, local lung distribution and chemokine gene expression.
|
21625544 |
2011 |
Lobar Pneumonia
|
0.300 |
Biomarker
|
disease |
CTD_human |
Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORγt cells in allergic inflammation, local lung distribution and chemokine gene expression.
|
21625544 |
2011 |
Endometrioma
|
0.300 |
Biomarker
|
disease |
CTD_human |
Molecular evidence for differences in endometrium in severe versus mild endometriosis.
|
21063030 |
2011 |
Endometrioma
|
0.300 |
Biomarker
|
disease |
CTD_human |
Unique transcriptome, pathways, and networks in the human endometrial fibroblast response to progesterone in endometriosis.
|
20864642 |
2011 |
Experimental Lung Inflammation
|
0.300 |
Biomarker
|
disease |
CTD_human |
Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORγt cells in allergic inflammation, local lung distribution and chemokine gene expression.
|
21625544 |
2011 |
Diabetes Mellitus, Insulin-Dependent
|
0.240 |
GeneticVariation
|
disease |
BEFREE |
Our findings indicate that the VDR FokI polymorphism and several VDR and IL-1-R1 haplotypes are associated with susceptibility to T1DM in the Dalmatian population.
|
16258158 |
2005 |
Diabetes Mellitus, Insulin-Dependent
|
0.240 |
Biomarker
|
disease |
MGD |
IL-1 receptor deficiency slows progression to diabetes in the NOD mouse.
|
14693705 |
2004 |
Diabetes Mellitus, Insulin-Dependent
|
0.240 |
GeneticVariation
|
disease |
BEFREE |
Characterization of new polymorphisms in the 5' UTR of the human interleukin-1 receptor type 1 (IL1R1) gene: linkage to type 1 diabetes and correlation to IL-1RI plasma level.
|
11197691 |
2000 |