|
Adenocarcinoma
|
0.370 |
AlteredExpression
|
group |
BEFREE |
All cases of adenocarcinoma showed strong expression of both RELA and NFκB-1.
|
26990751 |
2017 |
|
Adenocarcinoma
|
0.370 |
GeneticVariation
|
group |
LHGDN |
Clinical biology of esophageal adenocarcinoma after surgery is influenced by nuclear factor-kappaB expression.
|
17548685 |
2007 |
|
Adenocarcinoma
|
0.370 |
AlteredExpression
|
group |
LHGDN |
Morphoproteomic profile of mTOR, Ras/Raf kinase/ERK, and NF-kappaB pathways in human gastric adenocarcinoma.
|
18715846 |
2008 |
|
Adenocarcinoma
|
0.370 |
AlteredExpression
|
group |
LHGDN |
NF-kappaB-dependent MnSOD expression protects adenocarcinoma cells from TNF-alpha-induced apoptosis.
|
12032830 |
2002 |
|
Adenocarcinoma
|
0.370 |
Biomarker
|
group |
LHGDN |
Expression of nuclear factor-kappa B and I kappa B alpha proteins in prostatic adenocarcinomas: correlation of nuclear factor-kappa B immunoreactivity with disease recurrence.
|
15073126 |
2004 |
|
Adenocarcinoma
|
0.370 |
Biomarker
|
group |
LHGDN |
Use of bioluminescent imaging to investigate the role of nuclear factor-kappaBeta in experimental non-small cell lung cancer metastasis.
|
18008176 |
2008 |
|
Adenocarcinoma Of Esophagus
|
0.010 |
Biomarker
|
disease |
BEFREE |
H(2)O(2)-induced increase in NOX5-S expression was significantly inhibited by knockdown of nuclear factor (NF)-κB1 p50 with p50 small interfering RNA (siRNA) in EA cell lines FLO and OE33.
|
21750116 |
2011 |
|
Adenocarcinoma, Basal Cell
|
0.300 |
Biomarker
|
disease |
CTD_human |
Melatonin suppresses AOM/DSS-induced large bowel oncogenesis in rats.
|
19028472 |
2009 |
|
Adenocarcinoma, Oxyphilic
|
0.300 |
Biomarker
|
disease |
CTD_human |
Melatonin suppresses AOM/DSS-induced large bowel oncogenesis in rats.
|
19028472 |
2009 |
|
Adenocarcinoma, Tubular
|
0.300 |
Biomarker
|
disease |
CTD_human |
Melatonin suppresses AOM/DSS-induced large bowel oncogenesis in rats.
|
19028472 |
2009 |
|
Adenoid Cystic Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Among the detected alterations in gene expression, the only difference reaching statistical significance was in the case of NFkB1 in adenocystic carcinomas (p=0.05).
|
23603344 |
2013 |
|
Adenoma
|
0.010 |
GeneticVariation
|
group |
BEFREE |
The ABCB1 C-rs3789243-T and NFKB1 -94ins/del homozygous variant genotypes were associated with low ABCB1 mRNA levels in morphologically normal sigmoid tissue from adenoma cases (P<0.05 for both).
|
23977225 |
2013 |
|
Adenomatoid Tumor
|
0.010 |
Biomarker
|
disease |
BEFREE |
Additionally, all well-differentiated papillary mesothelioma demonstrated robust expression of L1 cell adhesion molecule (L1CAM), a marker of NF-kB pathway activation, similar to that observed in adenomatoid tumors.
|
30171198 |
2019 |
|
Adult Acute Lymphocytic Leukemia
|
0.010 |
Biomarker
|
disease |
BEFREE |
To investigate the possible role of inhibiting NF-kB activation in sensitizing tumor cells to chemotherapy-induced apoptosis, we transfected the dominant-negative mutant inhibitor of NF-kB (IkBm) into the EU-1 cell line, an acute lymphoblastic leukemia (ALL) line with constitutive NF-kB activation.
|
14603254 |
2003 |
|
Adult Burkitt Lymphoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Furthermore, Nfkb 1 expression was reduced in the majority of Emu-Myc lymphomas and was also suppressed in human Burkitt lymphoma.
|
15940251 |
2005 |
|
Adult Classical Hodgkin Lymphoma
|
0.020 |
Biomarker
|
disease |
BEFREE |
Reconstitution of wild-type TNFAIP3 in A20-deficient cHL cell lines revealed a significant decrease in transcripts of selected NF-kappaB target genes and caused cytotoxicity.
|
19380639 |
2009 |
|
Adult Classical Hodgkin Lymphoma
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
PMBLs share clinical, transcriptional and molecular features with classical Hodgkin lymphoma (cHL), including constitutive activation of NF-kB, JAK/STAT signaling and PD-1-mediated immune evasion.
|
31697821 |
2019 |
|
Adult Diffuse Large B-Cell Lymphoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
The results also provide insights into the regulation and function of p50 in diffuse large B-cell lymphoma and its cross talk with the p53 pathway with important therapeutic implications.
|
28281555 |
2017 |
|
Adult Fibrosarcoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Here, we report that defective responsiveness of TAM from a murine fibrosarcoma and human ovarian carcinoma to M1 activation signals was associated with a massive nuclear localization of the p50 nuclear factor-kappaB (NF-kappaB) inhibitory homodimer. p50 overexpression inhibited IL-12 expression in normal macrophages.
|
17145890 |
2006 |
|
Adult Glioblastoma
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
In this work, we report that the ectopic modulation of NF-kB modifies miR-221/222 expression in prostate carcinoma and glioblastoma cell lines, where we had previously shown their oncogenic activity.
|
21245048 |
2011 |
|
Adult Glioblastoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
In humans, low expression of Kip1 ubiquitination-promoting complex 1 (KPC1), a ubiquitin ligase required for p105 to p50 processing, was shown to correlate with a reduction in p50 and glioblastoma incidence.
|
26663363 |
2016 |
|
Adult Glioblastoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
Absence of host NF-κB p50 induces murine glioblastoma tumor regression, increases survival, and decreases T-cell induction of tumor-associated macrophage M2 polarization.
|
30030559 |
2018 |
|
Adult Hodgkin Lymphoma
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
A roadmap of constitutive NF-κB activity in Hodgkin lymphoma: Dominant roles of p50 and p52 revealed by genome-wide analyses.
|
26988706 |
2016 |
|
Adult Hodgkin Lymphoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
Sequenced chromatin immunoprecipitated DNA fragments (ChIP-Seq) analysis revealed an extensive NF-kB DNA-binding network in DLBCL and HL.
|
30941572 |
2019 |
|
Adult Hodgkin Lymphoma
|
0.030 |
GeneticVariation
|
disease |
BEFREE |
Polymorphic variation in NFKB1 and other aspirin-related genes and risk of Hodgkin lymphoma.
|
19223558 |
2009 |