|
Oral Ulcer
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci.
|
30837455 |
2019 |
|
Pneumocystis jiroveci pneumonia
|
0.090 |
Biomarker
|
disease |
BEFREE |
Our data suggest that core Frizzled/PCP factors, acting through RhoA and Rho kinase, regulate the function/activity of integrins and that integrins thus contribute to the complex interaction network of PCP signalling, cell adhesion and cytoskeletal elements required for a precise and synchronous 90° rotation movement.
|
31409231 |
2019 |
|
Pneumocystis jiroveci pneumonia
|
0.090 |
Biomarker
|
disease |
BEFREE |
A 10-year-old girl was referred to our hospital for the treatment of Pneumocystis Jirovecii Pneumonia (PCP: Pneumocystis pneumonia).
|
29138020 |
2018 |
|
Pneumocystis jiroveci pneumonia
|
0.090 |
Biomarker
|
disease |
BEFREE |
Pneumocystis pneumonia or PCP is caused by Pneumocystis jirovecii, an obligate parasite of the human lung.
|
15531210 |
2004 |
|
Pneumocystis jiroveci pneumonia
|
0.090 |
Biomarker
|
disease |
BEFREE |
The planar cell polarity (PCP) signaling pathway governs collective cell movements during vertebrate embryogenesis, and certain PCP proteins are also implicated in the assembly of cilia.
|
20671153 |
2010 |
|
Pneumocystis jiroveci pneumonia
|
0.090 |
Biomarker
|
disease |
BEFREE |
Expression of noncanonical Wnt-related genes was evaluated in 91 ACTs (66 children and 25 adults) by qPCR and the expression of beta-catenin, P53 and protein effectors of Wnt/Ca (NFAT) and Wnt/PCP (JNK) by immunohistochemistry.TP53 and CTNNB1 genes were sequenced.
|
24717047 |
2014 |
|
Pneumocystis jiroveci pneumonia
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
We analyzed the genetic variation among isolates of Pneumocystis jiroveci from Portuguese immunocompromised patients with PCP at the internal transcribed spacer (ITS) regions of the nuclear rRNA operon and at the dihydropteroate synthase (DHPS) gene.
|
14636689 |
2003 |
|
Pneumocystis jiroveci pneumonia
|
0.090 |
Biomarker
|
disease |
BEFREE |
Using this method, the viability of P.c. hominis in bronchoalveolar lavage fluids from patients developing PCP and in the environment of PCP patients was established.
|
11906051 |
2001 |
|
Pneumocystis jiroveci pneumonia
|
0.090 |
Biomarker
|
disease |
BEFREE |
Several decades ago, the presence of Pneumocystis morphotypes (trophic forms and cysts) was described in the lungs of normal cats and cats with experimentally induced symptomatic PCP (after immunosuppression by corticosteroids); yet to date spontaneous or drug-induced PCP has not been described in the clinical feline literature, despite immunosuppression of cats by long-standing retrovirus infections or after kidney transplantation.
|
30566653 |
2019 |
|
Pneumocystis jiroveci pneumonia
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
The identification of P. jirovecii internal transcribed spacer (ITS) types was performed on P. jirovecii isolates from the 18 RTRs (12 patients with Pneumocystis pneumonia [PCP], 6 colonized patients), 22 unlinked control patients (18 patients with PCP, 4 colonized patients), and 69 patients (34 patients with PCP, 35 colonized patients) with contemporaneously diagnosed P. jirovecii infections in the Brest geographic area.A transmission map was drawn up.
|
22337822 |
2012 |
|
Schizophrenia
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
Does phenylethylamine have a role in schizophrenia?: LSD and PCP up-regulate aromatic L-amino acid decarboxylase mRNA levels.
|
9387886 |
1997 |
|
Schizophrenia
|
0.060 |
Biomarker
|
disease |
BEFREE |
Kernel-based machine learning techniques quantified that the chronic PCP model represented schizophrenia brain changes most closely for four of these functional domains.
|
27335180 |
2016 |
|
Schizophrenia
|
0.060 |
Biomarker
|
disease |
BEFREE |
Interestingly, some behavioral indices associated with the positive symptoms of schizophrenia that were ameliorated in PAOPA's prior examination in the amphetamine-sensitized model of schizophrenia were not ameliorated in the PCP model; suggesting that the deficits induced by amphetamine and PCP-while phenotypically similar-are mechanistically different and that PAOPA's effects are restricted to certain mechanisms and systems.
|
30618660 |
2018 |
|
Schizophrenia
|
0.060 |
Biomarker
|
disease |
BEFREE |
>35% of patients with CMCs alone or CMCs and schizophrenia had prescriptions provided by 3 or more PCP providers, which increased to 49.1% for patients with CMCs and depression.
|
28274335 |
2017 |
|
Schizophrenia
|
0.060 |
Biomarker
|
disease |
BEFREE |
Synaptic biomarker reduction and impaired cognition in the sub-chronic PCP mouse model for schizophrenia.
|
31580184 |
2020 |
|
Schizophrenia
|
0.060 |
Biomarker
|
disease |
BEFREE |
PCP at doses of 3.0-5.0 mg/kg induced fMRI signal changes in several brain regions associated with SCZ.
|
28342897 |
2017 |
|
Pneumonia
|
0.040 |
Biomarker
|
disease |
BEFREE |
Four weeks later, CD4-depleted SP-A-deficient mice had developed a more severe Pneumocystis infection than CD4-depleted WT (P. carinii pneumonia [PCP] scores of 3 versus 2, respectively).
|
15385504 |
2004 |
|
Pneumonia
|
0.040 |
Biomarker
|
disease |
BEFREE |
The performance of the two assays was evaluated according to clinical categories (clinical <i>Pneumocystis</i> pneumonia [PCP], possible PCP, or unlikely PCP) based on clinical and radiological observations.
|
30430780 |
2019 |
|
Pneumonia
|
0.040 |
Biomarker
|
disease |
BEFREE |
The objectives were: (1) to test the sensitivity, specificity and prognostic value of PCR in diagnosis and follow up of PCP; (2) to investigate the eventual occurrence and role of asymptomatic carriers of P. carinii; (3) to evaluate the prognostic significance of blood PCR positivity versus respiratory samples; (4) to verify the occurrence of exogenous infections or endogenous reactivations in cases of recurrent P. carinii pneumonia; and (5) to study the possible correlation between P. carinii genotype identified and capability of blood dissemination, prior prophylactic treatments, clinical parameters and outcome of the patients.
|
11118878 |
2000 |
|
Pneumonia
|
0.040 |
GeneticVariation
|
disease |
BEFREE |
The fungal burden in patients with PJ pneumonia (PCP, n = 7) was also investigated.
|
28358900 |
2017 |
|
Papillary craniopharyngioma
|
0.040 |
Biomarker
|
disease |
BEFREE |
Expression of noncanonical Wnt-related genes was evaluated in 91 ACTs (66 children and 25 adults) by qPCR and the expression of beta-catenin, P53 and protein effectors of Wnt/Ca (NFAT) and Wnt/PCP (JNK) by immunohistochemistry.TP53 and CTNNB1 genes were sequenced.
|
24717047 |
2014 |
|
Papillary craniopharyngioma
|
0.040 |
Biomarker
|
disease |
BEFREE |
Using this method, the viability of P.c. hominis in bronchoalveolar lavage fluids from patients developing PCP and in the environment of PCP patients was established.
|
11906051 |
2001 |
|
Papillary craniopharyngioma
|
0.040 |
Biomarker
|
disease |
BEFREE |
Our data suggest that core Frizzled/PCP factors, acting through RhoA and Rho kinase, regulate the function/activity of integrins and that integrins thus contribute to the complex interaction network of PCP signalling, cell adhesion and cytoskeletal elements required for a precise and synchronous 90° rotation movement.
|
31409231 |
2019 |
|
Papillary craniopharyngioma
|
0.040 |
Biomarker
|
disease |
BEFREE |
The planar cell polarity (PCP) signaling pathway governs collective cell movements during vertebrate embryogenesis, and certain PCP proteins are also implicated in the assembly of cilia.
|
20671153 |
2010 |
|
Colorectal Carcinoma
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
3) PGI activity in CRC tissue correlated negatively with histological grade, tumor size and 5-year overall survival of CRC patients.
|
26078706 |
2015 |