|
Pituitary Diseases
|
0.020 |
Biomarker
|
group |
BEFREE |
This study was attempted to determine the gene expression profiles of transcription factors (Tpit, NeuroD1 and IKZF1), proprotein convertase (PC) 1/3 and PC2, and several key receptors linked to ACTH secretion, including corticotrophin releasing hormone receptor (CRHR1), vasopressin receptor 1b (V1bR), somatostatin receptor (SSTR) subtype-2, -5 and dopamine receptor type 2 (D2R) in non-pituitary and pituitary ACTH-secreting tumors.
|
21383526 |
2011 |
|
Pituitary-dependent Cushing's disease
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
CRHR, V1bR, and 11beta-HSD2 mRNA levels in CD were greater than those in SCA and NFT.
|
18057378 |
2007 |
|
Neoplasms
|
0.020 |
Biomarker
|
group |
BEFREE |
To investigate the role of the pituitary vasopressin (V3) receptor (R) in ACTH-secreting tumours we have qualitatively and quantitatively analysed its mRNA.
|
9876345 |
1998 |
|
Heart failure
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The regulation of APJR, V1aR and V1bR expression in the heart and the retroperitoneal adipose tissue were affected by both HF and HFD.
|
31645268 |
2019 |
|
Congestive heart failure
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
The regulation of APJR, V1aR and V1bR expression in the heart and the retroperitoneal adipose tissue were affected by both HF and HFD.
|
31645268 |
2019 |
|
Agnosia for Pain
|
0.010 |
Biomarker
|
disease |
BEFREE |
These findings indicate that inhibition of μ-opioid-receptor-associated V1bR provides an approach for enhancing morphine analgesia without increasing analgesic tolerance.
|
29713080 |
2018 |
|
Diabetes Mellitus
|
0.010 |
GeneticVariation
|
group |
BEFREE |
Four tag single nucleotide polymorphisms (SNPs: rs35810727, rs28373064, rs35439639, rs35608965) of AVPR1B were genotyped in the cardiovascular cohort (n=6103) of MDC (MDC-CC) and associated with measures of obesity and DM.
|
26503846 |
2016 |
|
Obesity
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Four tag single nucleotide polymorphisms (SNPs: rs35810727, rs28373064, rs35439639, rs35608965) of AVPR1B were genotyped in the cardiovascular cohort (n=6103) of MDC (MDC-CC) and associated with measures of obesity and DM.
|
26503846 |
2016 |
|
Anxiety
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
By contrast, genetic associations with lifetime diagnoses of depression and anxiety in SA or gene-environment interactions between AVPR1B variants and stressful life events (SLEs) were not significant.
|
23422793 |
2013 |
|
Depressive disorder
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
By contrast, genetic associations with lifetime diagnoses of depression and anxiety in SA or gene-environment interactions between AVPR1B variants and stressful life events (SLEs) were not significant.
|
23422793 |
2013 |
|
Melancholia
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
No association between polymorphisms and haplotypes of the AVPR1b, CRHR1 and NR3C1 genes and depression with melancholic features in the course of bipolar disorder.
|
23068076 |
2013 |
|
Unipolar Depression
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Epistatic interaction between CRHR1 and AVPR1b variants as a predictor of major depressive disorder.
|
23962971 |
2013 |
|
Depressed mood
|
0.010 |
GeneticVariation
|
phenotype |
BEFREE |
By contrast, genetic associations with lifetime diagnoses of depression and anxiety in SA or gene-environment interactions between AVPR1B variants and stressful life events (SLEs) were not significant.
|
23422793 |
2013 |
|
Suicidal
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
This study aims, for the first time, to investigate association of AVPR1B genetic variants with mood and anxiety outcomes in suicidal behavior.Using a family-based study design of 660 complete nuclear family trios with offspring who have made a suicide attempt (SA), we tested the direct association and linkage of AVPR1B single nucleotide polymorphisms (SNPs) with SA, as well as with depression and anxiety in SA.
|
23422793 |
2013 |
|
Major Depressive Disorder
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to analyze the possible association of CRHR1 and AVPR1b gene variants with bipolar disorder and major depressive disorder (MDD).
|
23962971 |
2013 |
|
ACTH Syndrome, Ectopic
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Higher expression of AVPR1B was observed in the EAS patients responsive to desmopressin, as well as in corticotrophic tumors, as compared with normal pituitary samples, but no correlation between AVPR1B expression and response to desmopressin was observed in the CD patients.
|
18426818 |
2008 |
|
Panic Disorder
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
These data suggest that polymorphisms in the AVPR1B and the CRHR1 genes alter the susceptibility to panic disorder.
|
18384079 |
2008 |
|
Cardiac Arrest
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
CRHR, V1bR, and 11beta-HSD2 mRNA levels in CD were greater than those in SCA and NFT.
|
18057378 |
2007 |
|
Small cell carcinoma of lung
|
0.010 |
Biomarker
|
disease |
BEFREE |
The occurrence of the V1bR/V3R is of 28 and 18% for SCLC and NSCLC, respectively.
|
16043261 |
2005 |
|
Recurrent major depressive episodes
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Five SNPs were identified in AVPR1b and genotyped in two well-diagnosed samples of patients with recurrent major depression and matched controls.
|
15094789 |
2004 |