|
Bipolar Disorder
|
0.330 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to analyze the possible association of CRHR1 and AVPR1b gene variants with bipolar disorder and major depressive disorder (MDD).
|
23962971 |
2013 |
|
Bipolar Disorder
|
0.330 |
Biomarker
|
disease |
PSYGENET |
The aim of this study was to analyze the possible association of CRHR1 and AVPR1b gene variants with bipolar disorder and major depressive disorder (MDD).
|
23962971 |
2013 |
|
Bipolar Disorder
|
0.330 |
GeneticVariation
|
disease |
BEFREE |
Our results suggest possible involvement of the AVPR1b and CRHR1 genes in the ethiology of psychotic features in the course of affective disorders, and possible involvement of CRHR1 gene in the ethiology of bipolar disorder.
|
24012103 |
2013 |
|
Mood Disorders
|
0.330 |
Biomarker
|
group |
PSYGENET |
Our results suggest possible involvement of the AVPR1b and CRHR1 genes in the ethiology of psychotic features in the course of affective disorders, and possible involvement of CRHR1 gene in the ethiology of bipolar disorder.
|
24012103 |
2013 |
|
Mood Disorders
|
0.330 |
Biomarker
|
group |
PSYGENET |
Polymorphisms of CRHR1 and AVPR1b may modify susceptibility to mood disorders.
|
23962971 |
2013 |
|
Mood Disorders
|
0.330 |
Biomarker
|
group |
BEFREE |
Polymorphisms of CRHR1 and AVPR1b may modify susceptibility to mood disorders.
|
23962971 |
2013 |
|
Bipolar Disorder
|
0.330 |
Biomarker
|
disease |
PSYGENET |
Association between functional polymorphism of the AVPR1b gene and polymorphism rs1293651 of the CRHR1 gene and bipolar disorder with psychotic features.
|
22341483 |
2012 |
|
Bipolar Disorder
|
0.330 |
GeneticVariation
|
disease |
BEFREE |
Association between functional polymorphism of the AVPR1b gene and polymorphism rs1293651 of the CRHR1 gene and bipolar disorder with psychotic features.
|
22341483 |
2012 |
|
Mood Disorders
|
0.330 |
GeneticVariation
|
group |
BEFREE |
We genotyped single nucleotide polymorphisms (SNPs) across the AVPR1B gene in a family-based sample with childhood-onset mood disorders.
|
17909131 |
2007 |
|
Mood Disorders
|
0.330 |
Biomarker
|
group |
PSYGENET |
We genotyped single nucleotide polymorphisms (SNPs) across the AVPR1B gene in a family-based sample with childhood-onset mood disorders.
|
17909131 |
2007 |
|
Mood Disorders
|
0.330 |
Biomarker
|
group |
PSYGENET |
We examined whether genetic variations in the AVP receptor 1b gene (AVPR1b) could be associated with increased susceptibility to affective disorders using a gene-based association analysis of single-nucleotide polymorphisms (SNPs).
|
15094789 |
2004 |
|
Mood Disorders
|
0.330 |
GeneticVariation
|
group |
BEFREE |
We examined whether genetic variations in the AVP receptor 1b gene (AVPR1b) could be associated with increased susceptibility to affective disorders using a gene-based association analysis of single-nucleotide polymorphisms (SNPs).
|
15094789 |
2004 |
|
Anxiety Disorders
|
0.220 |
Therapeutic
|
group |
RGD |
Vasopressin V1B receptor antagonists may be effective for the treatment of depression and anxiety and the objective of this study was to characterize the pharmacological profiles of two newly synthesized arginine vasopressin receptor 1B (V1B receptor) antagonists, TASP0233278 and TASP0390325.
|
24654684 |
2014 |
|
Anxiety Disorders
|
0.220 |
GeneticVariation
|
group |
BEFREE |
By contrast, genetic associations with lifetime diagnoses of depression and anxiety in SA or gene-environment interactions between AVPR1B variants and stressful life events (SLEs) were not significant.
|
23422793 |
2013 |
|
Anxiety Disorders
|
0.220 |
Biomarker
|
group |
BEFREE |
The vasopressin receptor type 1b (AVPR1B) is mainly expressed by pituitary corticotropes and it mediates the stimulatory effects of AVP on ACTH release; common AVPR1B haplotypes have been involved in mood and anxiety disorders in humans, while rodents lacking a functional receptor gene display behavioral defects and altered stress responses.
|
19486526 |
2009 |
|
Mental Depression
|
0.210 |
Therapeutic
|
disease |
RGD |
Vasopressin V1B receptor antagonists may be effective for the treatment of depression and anxiety and the objective of this study was to characterize the pharmacological profiles of two newly synthesized arginine vasopressin receptor 1B (V1B receptor) antagonists, TASP0233278 and TASP0390325.
|
24654684 |
2014 |
|
Mental Depression
|
0.210 |
GeneticVariation
|
disease |
BEFREE |
By contrast, genetic associations with lifetime diagnoses of depression and anxiety in SA or gene-environment interactions between AVPR1B variants and stressful life events (SLEs) were not significant.
|
23422793 |
2013 |
|
Alcoholic Intoxication, Chronic
|
0.200 |
Biomarker
|
disease |
RGD |
Evidence that vasopressin V1b receptors mediate the transition to excessive drinking in ethanol-dependent rats.
|
21309953 |
2012 |
|
Alcohol-Related Disorders
|
0.200 |
Biomarker
|
group |
RGD |
Evidence that vasopressin V1b receptors mediate the transition to excessive drinking in ethanol-dependent rats.
|
21309953 |
2012 |
|
Alcohol-Induced Disorders
|
0.200 |
Biomarker
|
group |
RGD |
Evidence that vasopressin V1b receptors mediate the transition to excessive drinking in ethanol-dependent rats.
|
21309953 |
2012 |
|
ALCOHOL DEPENDENCE, PROTECTION AGAINST
|
0.200 |
Biomarker
|
phenotype |
RGD |
Evidence that vasopressin V1b receptors mediate the transition to excessive drinking in ethanol-dependent rats.
|
21309953 |
2012 |
|
AERODIGESTIVE TRACT CANCER, SQUAMOUS CELL, ALCOHOL-RELATED, PROTECTION AGAINST
|
0.200 |
Biomarker
|
phenotype |
RGD |
Evidence that vasopressin V1b receptors mediate the transition to excessive drinking in ethanol-dependent rats.
|
21309953 |
2012 |
|
Pituitary Diseases
|
0.020 |
AlteredExpression
|
group |
BEFREE |
Within the MBHv/ME and anterior pituitary, a gradual increase of AVT mRNA in PVN as well as MBHv/ME was associated with significant upregulation of V1bR (p < 0.
|
31622604 |
2020 |
|
Pituitary-dependent Cushing's disease
|
0.020 |
Biomarker
|
disease |
BEFREE |
All evaluated proteins [USP8, arginine vasopressin receptor 1b and 2, corticotropin-releasing hormone receptor, cAMP response element-binding protein (CREB), p27/kip1, cyclin E, heat shock protein 90 (HSP90), orphan nuclear receptor 4, epidermal growth factor receptor, histone deacetylase 2, glucocorticoid receptor, cyclin-dependent kinase 5 and Abelson murine leukemia viral oncogene homolog 1 enzyme substrate 1] were known to be deregulated in CD.
|
30844069 |
2019 |
|
Neoplasms
|
0.020 |
Biomarker
|
group |
BEFREE |
This study was attempted to determine the gene expression profiles of transcription factors (Tpit, NeuroD1 and IKZF1), proprotein convertase (PC) 1/3 and PC2, and several key receptors linked to ACTH secretion, including corticotrophin releasing hormone receptor (CRHR1), vasopressin receptor 1b (V1bR), somatostatin receptor (SSTR) subtype-2, -5 and dopamine receptor type 2 (D2R) in non-pituitary and pituitary ACTH-secreting tumors.
|
21383526 |
2011 |