Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
T357A variant has a significantly higher frequency in nonencapsulated tumors than wild type SCCA1 (p = 0.034).The SCCA1, 2 mRNA is effective for detecting HCC and could be potentially applied in HCC diagnosis.
|
25150316 |
2014 |
Liver carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
T357A variant has a significantly higher frequency in nonencapsulated tumors than wild type SCCA1 (p = 0.034).The SCCA1, 2 mRNA is effective for detecting HCC and could be potentially applied in HCC diagnosis.
|
25150316 |
2014 |
Chronic liver disease
|
0.030 |
GeneticVariation
|
group |
BEFREE |
Squamous cell carcinoma antigen-1 (SERPINB3) polymorphism in chronic liver disease.
|
18657489 |
2009 |
Hepatitis C
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
To explore SCCA-1 polymorphism in patients with HCV infection as single etiologic factor and different extent of liver disease.
|
18657489 |
2009 |
Liver diseases
|
0.010 |
GeneticVariation
|
group |
BEFREE |
To explore SCCA-1 polymorphism in patients with HCV infection as single etiologic factor and different extent of liver disease.
|
18657489 |
2009 |
Liver neoplasms
|
0.010 |
GeneticVariation
|
group |
BEFREE |
A novel SCCA1 variant has been identified in one third of liver tumours.
|
14970861 |
2004 |
melanoma
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Here we show that somatic mutations in SERPINB3 and SERPINB4 are associated with survival after anti-CTLA4 immunotherapy in two independent cohorts of patients with melanoma (n = 174).
|
27668655 |
2016 |
Squamous cell carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
We recently found that the squamous cell carcinoma antigens 1 (SCCA1) and SCCA2 are novel biomarkers of bronchial asthma, downstream of IL-4 and IL-13.
|
16238792 |
2005 |
Squamous cell carcinoma
|
0.400 |
Biomarker
|
disease |
CTD_human |
Proteomics of buccal squamous cell carcinoma: the involvement of multiple pathways in tumorigenesis.
|
15274141 |
2004 |
Squamous cell carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
The SCCA1 promoter was analyzed by dual luciferase assay and substituted with the E1A promoter to construct the oncolytic adenovirus to determine the squamous cell carcinoma-specific cell lysis.
|
20527047 |
2010 |
Squamous cell carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
This study examined the effect of squamous cell carcinoma antigen 1 (SCCA1) and SCCA2 on TNF-alpha-induced cell death in human oral squamous cell carcinoma cell lines.
|
16006770 |
2005 |
Squamous cell carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Squamous cell carcinoma antigens 1 and 2 (SCCA1 and 2, SERPIN B3 and B4), members of the ovalbumin serpin (ov-serpin)/clade B serpin family, were originally discovered as tumor-specific antigens and are used as tumor markers for various kinds of squamous cell carcinomas.
|
29642409 |
2018 |
Squamous cell carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
These findings suggest that the transcriptional regulation of SCCA1 and SCCA2 might differ among squamous cell carcinoma, keratinocyte and adenocarcinoma cells, and that SCCA1 promoter might be a potential target of gene therapy for squamous cell carcinoma.
|
11267667 |
2001 |
Squamous cell carcinoma
|
0.400 |
Biomarker
|
disease |
LHGDN |
Regulation of squamous cell carcinoma antigen production by E-cadherin mediated cell-cell adhesion in squamous cell carcinoma cell line.
|
14719077 |
2004 |
Squamous cell carcinoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
This suggests that combined measurements of both serum SCCA1 and SCCA2 concentrations can be very useful for distinguishing sinonasal inverted papilloma from SCC.
|
30376194 |
2018 |
Squamous cell carcinoma
|
0.400 |
Biomarker
|
disease |
LHGDN |
Evaluation of serum squamous cell carcinoma antigen as a novel biomarker for diagnosis of hepatocellular carcinoma in Egyptian patients.
|
19112206 |
2009 |
Esophageal Neoplasms
|
0.320 |
Biomarker
|
group |
BEFREE |
Squamous cell carcinoma antigen 1 is associated to poor prognosis in esophageal cancer through immune surveillance impairment and reduced chemosensitivity.
|
30825353 |
2019 |
Esophageal Neoplasms
|
0.320 |
Biomarker
|
group |
CTD_human |
Comparative proteomic analysis of esophageal squamous cell carcinoma.
|
15986332 |
2005 |
Malignant neoplasm of esophagus
|
0.310 |
Biomarker
|
disease |
BEFREE |
Squamous cell carcinoma antigen 1 is associated to poor prognosis in esophageal cancer through immune surveillance impairment and reduced chemosensitivity.
|
30825353 |
2019 |
Malignant neoplasm of esophagus
|
0.310 |
Biomarker
|
disease |
CTD_human |
Comparative proteomic analysis of esophageal squamous cell carcinoma.
|
15986332 |
2005 |
Spontaneous abortion
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
Gene expression in cultured endometrium from women with different outcomes following IVF.
|
18539642 |
2008 |
Abortion, Tubal
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
Gene expression in cultured endometrium from women with different outcomes following IVF.
|
18539642 |
2008 |
Contact Dermatitis
|
0.300 |
Biomarker
|
disease |
CTD_human |
Genes specifically modulated in sensitized skins allow the detection of sensitizers in a reconstructed human skin model. Development of the SENS-IS assay.
|
25724174 |
2015 |
Mouth Neoplasms
|
0.300 |
Biomarker
|
group |
CTD_human |
Proteomics of buccal squamous cell carcinoma: the involvement of multiple pathways in tumorigenesis.
|
15274141 |
2004 |
Precancerous Conditions
|
0.300 |
Biomarker
|
group |
CTD_human |
Comparative proteomic analysis of esophageal squamous cell carcinoma.
|
15986332 |
2005 |