SPP1, secreted phosphoprotein 1, 6696

N. diseases: 824; N. variants: 13
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.500 SusceptibilityMutation disease ORPHANET Recent insights into the genetic basis of systemic lupus erythematosus. 19440199 2009
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.500 SusceptibilityMutation disease ORPHANET Data on rs7574865 in the STAT4 gene and rs9138 in SPP1 were replicated for associations with SLE when comparing cases and controls (corrected P values ranging from 0.0043 to 0.027). 24023622 2013
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.500 Biomarker disease HPO
CUI: C0033687
Disease: Proteinuria
Proteinuria 		0.400 Biomarker phenotype HPO
CUI: C0024138
Disease: Lupus Erythematosus, Discoid
Lupus Erythematosus, Discoid 		0.150 Biomarker disease HPO
CUI: C0003864
Disease: Arthritis
Arthritis 		0.120 Biomarker disease HPO
CUI: C0027121
Disease: Myositis
Myositis 		0.120 Biomarker disease HPO
CUI: C0338656
Disease: Impaired cognition
Impaired cognition 		0.120 Biomarker disease HPO
CUI: C1565489
Disease: Renal Insufficiency
Renal Insufficiency 		0.120 Biomarker disease HPO
CUI: C0002170
Disease: Alopecia
Alopecia 		0.110 Biomarker disease HPO
CUI: C0003962
Disease: Ascites
Ascites 		0.110 Biomarker phenotype HPO
CUI: C0011991
Disease: Diarrhea
Diarrhea 		0.110 Biomarker phenotype HPO
CUI: C0027697
Disease: Nephritis
Nephritis 		0.110 Biomarker disease HPO
CUI: C0032227
Disease: Pleural effusion disorder
Pleural effusion disorder 		0.110 Biomarker group HPO
CUI: C0040034
Disease: Thrombocytopenia
Thrombocytopenia 		0.110 Biomarker phenotype HPO
CUI: C0000731
Disease: Abdomen distended
Abdomen distended 		0.100 Biomarker phenotype HPO
CUI: C0000737
Disease: Abdominal Pain
Abdominal Pain 		0.100 Biomarker phenotype HPO
CUI: C0003862
Disease: Arthralgia
Arthralgia 		0.100 Biomarker phenotype HPO
CUI: C0008031
Disease: Chest Pain
Chest Pain 		0.100 Biomarker phenotype HPO
CUI: C0013404
Disease: Dyspnea
Dyspnea 		0.100 Biomarker phenotype HPO
CUI: C0015967
Disease: Fever
Fever 		0.100 Biomarker phenotype HPO
CUI: C0018681
Disease: Headache
Headache 		0.100 Biomarker phenotype HPO
CUI: C0018965
Disease: Hematuria
Hematuria 		0.100 Biomarker phenotype HPO
CUI: C0018991
Disease: Hemiplegia
Hemiplegia 		0.100 Biomarker phenotype HPO
CUI: C0023015
Disease: Language Disorders
Language Disorders 		0.100 Biomarker group HPO