|
cervical cancer
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Polymorphisms of VEGF genes may affect cancer susceptibility and survival of early cervical cancer by modulating tumor angiogenesis.
|
20797778 |
2010 |
|
cervical cancer
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The goal of this study was to investigate polymorphisms in genes related to angiogenesis (PAI-1-675 4G/5G, VEGF C936T, and TGF-β1 G-800A) to evaluate the risk for developing uterine cervical cancer (UCC).
|
23873179 |
2013 |
|
cervical cancer
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Specific VEGF variants (rs699947, rs1570360) and haplotype (CTGCCAG) may contribute to the development of CC among Tunisian women.
|
25541433 |
2015 |
|
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
In contrast to normal cervical tissue, we found a highly significant co-expression (P<0.0001) between MMP-9 and VEGF(189) in cervical cancer.
|
12189553 |
2002 |
|
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
The results of the present study suggested that TSLP derived of cervical cancer cells may indirectly stimulate angiogenesis of HUVECs, by upregulating IL-8 and VEGF production, in a co-culture model between cervical cancer cells and EOS, therefore promoting the development of cervical cancer.
|
29344192 |
2017 |
|
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
The aim of this study was to determine whether VEGF/VEGFRs could be used as prognostic biomarkers in patients with CC.
|
31236742 |
2019 |
|
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
Furthermore, selective gene silencing of vascular endothelial growth factor and/or the telomerase catalytic subunit (i.e. telomerase reverse transcriptase) potently inhibits the growth of cervical cancer and laryngeal squamous cancer in mice.4.
|
19566820 |
2010 |
|
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
In the total CC, stage I, and stage II groups, all tested parameters showed statistically significant area under the receiver operating characteristics curve (AUC), but maximum range was obtained for the combination VEGF + SCC-Ag (I: 0.9146, II: 0.8941, III + IV: 0.9139, total CC group: 0.9347).
|
30037277 |
2018 |
|
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
Our findings have demonstrated that the miR-196b/HOXB7/VEGF pathway plays an important role in cervical cancer progression; hence targeting this pathway could be a promising therapeutic strategy for the future management of this disease.
|
23861821 |
2013 |
|
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
Although anti-vascular endothelial growth factor drugs have shown great promise as a therapeutic target for treatment of advanced cervical cancer, drug resistance and class-specific side effects negate long-term benefits.
|
28720059 |
2017 |
|
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
Vascular endothelial growth factor (VEGF) has emerged as a therapeutic target in several malignancies, including cervical cancer.
|
29666026 |
2018 |
|
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
Effects of VEGF suppression by small hairpin RNA interference combined with radiotherapy on the growth of cervical cancer.
|
25061734 |
2014 |
|
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
Prognostic role of vascular endothelial growth factor in cervical cancer: a meta-analysis.
|
28177889 |
2017 |
|
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
CD31 and vascular endothelial growth factor (VEGF) were stained to reflect tumor angiogenesis in 67 CC tissues.
|
30458457 |
2018 |
|
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
Deregulation of LIMD1-VHL-HIF-1α-VEGF pathway is associated with different stages of cervical cancer.
|
29654110 |
2018 |
|
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
To figure out the involved signaling pathways, we applied specific inhibitors for ERK/MAPK, JNK, and PI3K/Akt signaling pathways, respectively, to VEGFa-overexpressing cervical cancer lines and found that only inhibition of PI3K/Akt signal transduction abolished VEGFa-induced increases in cell growth and invasiveness.
|
25135429 |
2014 |
|
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
In this study, we have investigated the role of endoglin (CD105), a regulator of transforming growth factor (TGF)-beta(1) signalling on endothelial cells, basic fibroblast growth factor (bFGF) and vascular endothelial growth factor-A (VEGF-A) in cervical cancer.
|
19352388 |
2009 |
|
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
Our study demonstrates that the promoters for MK and VEGF are active in cervical cancer.
|
15368588 |
2004 |
|
cervical cancer
|
0.400 |
Biomarker
|
disease |
CTD_human |
PIAS3, SHP2 and SOCS3 Expression patterns in Cervical Cancers: Relevance with activation and resveratrol-caused inactivation of STAT3 signaling.
|
26432044 |
2015 |
|
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
The present study investigated the clinicopathological significance of the coexpression of LAPTM4B-35 and VEGF in patients with cervical cancer.
|
26526574 |
2016 |
|
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
RNA interference of HPV E6/E7 or VEGF expression implies an effective anti-cervical cancer strategy.
|
21222176 |
2011 |
|
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Hypoxia-inducible factor 1alpha affects the proliferation, apoptosis, and migration of UCC SiHa cells in part by regulating the expression of its target genes such as VEGF, HGTD-P, and CXCR4.
|
19574782 |
2009 |
|
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
VEGF expression is significantly positively correlated with miR-21 expression, and the high levels of VEGF and miR-21 predict unfavorable prognosis of cervical cancer.
|
30338794 |
2018 |
|
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Furthermore, IP-10 levels significantly reverse-correlated with vascular endothelial growth factor (VEGF) levels in uterine cervical cancers.
|
17505511 |
2007 |
|
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
The mRNA expression level of TLR8 in the patients with cervical cancer and Hela cells were up-regulated, it consistent with the increased expression of VEGF and Bcl-2.
|
24782650 |
2014 |