|
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
These findings provide evidence that the expression of VEGF is involved in the promotion of angiogenesis in cervical cancer and plays an important role in early invasion.
|
10448304 |
1999 |
|
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
In contrast to normal cervical tissue, we found a highly significant co-expression (P<0.0001) between MMP-9 and VEGF(189) in cervical cancer.
|
12189553 |
2002 |
|
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Expression of cyclooxygenase-1 and -2 associated with expression of VEGF in primary cervical cancer and at metastatic lymph nodes.
|
12821346 |
2003 |
|
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
Our study demonstrates that the promoters for MK and VEGF are active in cervical cancer.
|
15368588 |
2004 |
|
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Furthermore, IP-10 levels significantly reverse-correlated with vascular endothelial growth factor (VEGF) levels in uterine cervical cancers.
|
17505511 |
2007 |
|
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
VEGF and TGF-beta1 mRNA overexpression was found to be associated with progression from low-grade to high-grade cervical intraepithelial neoplasia (CIN), while YY1 showed constitutively elevated transcript levels in CIN and cervical cancer compared to controls.
|
17549406 |
2007 |
|
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Thus, we investigated whether E6 oncoprotein could regulate VEGF expression in HPV18-positive cervical cancer-derived HeLa cells harboring a wild-type p53.
|
17678892 |
2007 |
|
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
In this study, we have investigated the role of endoglin (CD105), a regulator of transforming growth factor (TGF)-beta(1) signalling on endothelial cells, basic fibroblast growth factor (bFGF) and vascular endothelial growth factor-A (VEGF-A) in cervical cancer.
|
19352388 |
2009 |
|
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
Furthermore, selective gene silencing of vascular endothelial growth factor and/or the telomerase catalytic subunit (i.e. telomerase reverse transcriptase) potently inhibits the growth of cervical cancer and laryngeal squamous cancer in mice.4.
|
19566820 |
2010 |
|
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Hypoxia-inducible factor 1alpha affects the proliferation, apoptosis, and migration of UCC SiHa cells in part by regulating the expression of its target genes such as VEGF, HGTD-P, and CXCR4.
|
19574782 |
2009 |
|
cervical cancer
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Polymorphisms of VEGF genes may affect cancer susceptibility and survival of early cervical cancer by modulating tumor angiogenesis.
|
20797778 |
2010 |
|
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
VEGF expression and microvascular density of cervical cancer tissues were detected with immunohistochemistry and CD34 labeling respectively to elucidate the pathway by which EFEMP1 influences the growth of cervical cancer.
|
21163514 |
2011 |
|
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
RNA interference of HPV E6/E7 or VEGF expression implies an effective anti-cervical cancer strategy.
|
21222176 |
2011 |
|
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
We have provided compelling evidence that ERRα affects VEGF expression and tumor growth in cervical cancer.
|
21546870 |
2011 |
|
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
The data suggested that inhibited VEGF expression enhances radiosensitivity in cervical cancer therapy.
|
23193915 |
2012 |
|
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
Our findings have demonstrated that the miR-196b/HOXB7/VEGF pathway plays an important role in cervical cancer progression; hence targeting this pathway could be a promising therapeutic strategy for the future management of this disease.
|
23861821 |
2013 |
|
cervical cancer
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The goal of this study was to investigate polymorphisms in genes related to angiogenesis (PAI-1-675 4G/5G, VEGF C936T, and TGF-β1 G-800A) to evaluate the risk for developing uterine cervical cancer (UCC).
|
23873179 |
2013 |
|
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
To detect vascular endothelial growth factor (VEGF)-C mRNA expression in surgically resected tissues of 'pathologic N0' (pN0) cervical cancer; to investigate the relevance of VEGF-C mRNA expression to clinicopathological factors, lymph node recurrence and prognosis in early stage cervical cancer.
|
23963849 |
2013 |
|
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Function of inducible nitric oxide synthase in the regulation of cervical cancer cell proliferation and the expression of vascular endothelial growth factor.
|
24297386 |
2014 |
|
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
The mRNA expression level of TLR8 in the patients with cervical cancer and Hela cells were up-regulated, it consistent with the increased expression of VEGF and Bcl-2.
|
24782650 |
2014 |
|
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
Effects of VEGF suppression by small hairpin RNA interference combined with radiotherapy on the growth of cervical cancer.
|
25061734 |
2014 |
|
cervical cancer
|
0.400 |
Biomarker
|
disease |
BEFREE |
To figure out the involved signaling pathways, we applied specific inhibitors for ERK/MAPK, JNK, and PI3K/Akt signaling pathways, respectively, to VEGFa-overexpressing cervical cancer lines and found that only inhibition of PI3K/Akt signal transduction abolished VEGFa-induced increases in cell growth and invasiveness.
|
25135429 |
2014 |
|
cervical cancer
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Specific VEGF variants (rs699947, rs1570360) and haplotype (CTGCCAG) may contribute to the development of CC among Tunisian women.
|
25541433 |
2015 |
|
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
To investigate the effect of recombinant human p53 adenovirus injection combined with paclitaxel on human cervical cancer HeLa cell proliferation, apoptosis and expression of vascular endothelial growth factor (VEGF).
|
25855930 |
2015 |
|
cervical cancer
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Data have shown that VEGF expression levels are associated with hTERT expressions and telomerase activity in HPV-positive cervical cancer tissues and cells.
|
26067630 |
2015 |