|
Asthma
|
0.400 |
Biomarker
|
disease |
BEFREE |
The cytokine and potent angiogenic factor vascular endothelial growth factor (VEGF) plays an important role in airway remodelling in various airway diseases such as idiopathic pulmonary fibrosis, pulmonary hypertension, lung cancer, asthma and chronic obstructive pulmonary disease (COPD).
|
17906365 |
2007 |
|
Asthma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Experimental models and expression studies suggest that anti-vascular endothelial growth factor (VEGF) receptor strategies may be of use in patients with emphysema, whereas anti-HER1-directed strategies may be more useful in patients with pulmonary mucus hypersecretion, as seen in chronic bronchitis and asthma.
|
17406066 |
2007 |
|
Asthma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Relationship between neurokinin 2 receptor gene polymorphisms and serum vascular endothelial growth factor levels in patients with toluene diisocyanate-induced asthma.
|
16961715 |
2006 |
|
Asthma
|
0.400 |
Biomarker
|
disease |
LHGDN |
Immunomodulatory role of vascular endothelial growth factor and angiopoietin-1 in airway remodeling.
|
17168735 |
2006 |
|
Asthma
|
0.400 |
Biomarker
|
disease |
LHGDN |
Vascular endothelial growth factor-mediated induction of angiogenesis by human rhinoviruses.
|
16461129 |
2006 |
|
Asthma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
We sought to evaluate the effects of variations in the gene coding VEGF receptor (VEGFR) 2 on intermediate phenotypes of asthma in the Korean population.
|
16630933 |
2006 |
|
Asthma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
VEGF levels were measured in respiratory secretions from patients with asthma, before and during rhinovirus-induced exacerbations.
|
16461129 |
2006 |
|
Asthma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Nasal VEGF was also measured in a cohort of asthmatics with verified rhinovirus and respiratory syncytial virus (RSV) infection.
|
16555282 |
2006 |
|
Asthma
|
0.400 |
AlteredExpression
|
disease |
LHGDN |
Administration of VEGF receptor inhibitors reduced the pathophysiologic signs of asthma and decreased the increased expression of MMP-9 after ovalbumin inhalation.
|
16645174 |
2006 |
|
Asthma
|
0.400 |
Biomarker
|
disease |
CTD_human |
Acute and chronic changes of vascular endothelial growth factor (VEGF) in induced sputum of toluene diisocyanate (TDI)-induced asthma patients.
|
15201500 |
2004 |
|
Asthma
|
0.400 |
Biomarker
|
disease |
BEFREE |
We conclude that ASM-derived VEGF, through modulation of the extracellular matrix, may play an important role in airway remodeling seen in asthma.
|
14633511 |
2004 |
|
Asthma
|
0.400 |
Biomarker
|
disease |
LHGDN |
Vascular endothelial growth factor-induced secretion of fibronectin is ERK dependent.
|
14633511 |
2004 |
|
Asthma
|
0.400 |
Biomarker
|
disease |
LHGDN |
Acute and chronic changes of vascular endothelial growth factor (VEGF) in induced sputum of toluene diisocyanate (TDI)-induced asthma patients.
|
15201500 |
2004 |
|
Asthma
|
0.400 |
Biomarker
|
disease |
CTD_human |
One of the histological hallmarks of inflammation is angiogenesis, but the possible role of vascular endothelial growth factor (VEGF), a potent angiogenic cytokine, in TDI-induced asthma is unknown.
|
11907124 |
2002 |
|
Asthma
|
0.400 |
Biomarker
|
disease |
BEFREE |
These findings provide evidence that VEGF may play an important role in angiogenesis and subsequent airway remodeling in bronchial asthma.
|
11398081 |
2001 |