VEGFA, vascular endothelial growth factor A, 7422

N. diseases: 1899; N. variants: 59
Disease: Asthma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004096
Disease: Asthma
Asthma 		0.400 Biomarker disease BEFREE Vascular endothelial growth factor (VEGF) has been implicated in inflammatory and airway blood vessel remodeling in asthmatics. 27579513 2016
CUI: C0004096
Disease: Asthma
Asthma 		0.400 AlteredExpression disease BEFREE PDGFBB and VEGF levels were significantly associated with asthma. 31586492 2019
CUI: C0004096
Disease: Asthma
Asthma 		0.400 Biomarker disease BEFREE Abnormal histone methylation is responsible for increased vascular endothelial growth factor 165a secretion from airway smooth muscle cells in asthma. 22689881 2012
CUI: C0004096
Disease: Asthma
Asthma 		0.400 Biomarker disease BEFREE Importantly, MFG-E8 apparently alleviated OVA-driven airway remodeling, which were evidenced by declined secretion of important mediators of airway remodeling, including transforming growth factor-β1, matrix metalloproteinase 9, ADAM8, and vascular endothelial growth factor, and reduced airway collagen deposition and inhibited goblet cell hyperplasia in OVA-induced asthma in mice. 30076648 2018
CUI: C0004096
Disease: Asthma
Asthma 		0.400 Biomarker disease BEFREE These findings provide evidence that VEGF may play an important role in angiogenesis and subsequent airway remodeling in bronchial asthma. 11398081 2001
CUI: C0004096
Disease: Asthma
Asthma 		0.400 Biomarker disease CTD_human Acute and chronic changes of vascular endothelial growth factor (VEGF) in induced sputum of toluene diisocyanate (TDI)-induced asthma patients. 15201500 2004
CUI: C0004096
Disease: Asthma
Asthma 		0.400 Biomarker disease CTD_human Manganese (II) induces chemical hypoxia by inhibiting HIF-prolyl hydroxylase: implication in manganese-induced pulmonary inflammation. 19263519 2009
CUI: C0004096
Disease: Asthma
Asthma 		0.400 Biomarker disease CTD_human One of the histological hallmarks of inflammation is angiogenesis, but the possible role of vascular endothelial growth factor (VEGF), a potent angiogenic cytokine, in TDI-induced asthma is unknown. 11907124 2002
CUI: C0004096
Disease: Asthma
Asthma 		0.400 Biomarker disease LHGDN The aim of this study was to compare vascular endothelial growth factor (VEGF) and its receptor foetal liver kinase (Flk)-1 expression between seasonal AR patients with or without asthma and non-allergic controls as well as that between AR patients with and without asthma. 17651148 2007
CUI: C0004096
Disease: Asthma
Asthma 		0.400 Biomarker disease LHGDN Immunomodulatory role of vascular endothelial growth factor and angiopoietin-1 in airway remodeling. 17168735 2006
CUI: C0004096
Disease: Asthma
Asthma 		0.400 Biomarker disease LHGDN Vascular endothelial growth factor-mediated induction of angiogenesis by human rhinoviruses. 16461129 2006
CUI: C0004096
Disease: Asthma
Asthma 		0.400 AlteredExpression disease LHGDN Vascular endothelial growth factor overexpression in induced sputum of children with bronchial asthma. 18298425 2009
CUI: C0004096
Disease: Asthma
Asthma 		0.400 AlteredExpression disease LHGDN Administration of VEGF receptor inhibitors reduced the pathophysiologic signs of asthma and decreased the increased expression of MMP-9 after ovalbumin inhalation. 16645174 2006
CUI: C0004096
Disease: Asthma
Asthma 		0.400 Biomarker disease LHGDN Vascular endothelial growth factor-induced secretion of fibronectin is ERK dependent. 14633511 2004
CUI: C0004096
Disease: Asthma
Asthma 		0.400 Biomarker disease LHGDN Acute and chronic changes of vascular endothelial growth factor (VEGF) in induced sputum of toluene diisocyanate (TDI)-induced asthma patients. 15201500 2004