VIM, vimentin, 7431

N. diseases: 644; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0280217
Disease: stage, non-small cell lung cancer
stage, non-small cell lung cancer
0.010 AlteredExpression disease BEFREE Herein, we investigated the associations between clinicopathological parameters and VIM/E-cad expression in primary T1 stage non-small cell lung cancer (NSCLC). 28592120 2019
Acantholytic squamous cell carcinoma
0.010 AlteredExpression disease BEFREE Several cases of oral ASCC also expressed vimentin and cytokeratin (CK) 19, markers associated with epithelial-mesenchymal transition. 31706621 2019
CUI: C0334492
Disease: Malignant mesenchymal tumor
Malignant mesenchymal tumor
0.010 Biomarker disease BEFREE On histopathology, we found malignant mesenchymal tumor positive for vimentin and cluster of differentiation 10 (CD10). 31523571 2019
CUI: C0344460
Disease: Carcinoma ex pleomorphic adenoma
Carcinoma ex pleomorphic adenoma
0.010 Biomarker disease BEFREE To investigate C-myc, Ki-67, pan-cytokeratin, and vimentin immunohistochemical features of carcinoma ex pleomorphic adenoma (Ca-ex-PA) and pleomorphic adenoma (PA) in the lacrimal gland in order to find some clues in the differential diagnosis between them. 31456912 2019
CUI: C0521720
Disease: Corneal fibrosis
Corneal fibrosis
0.010 Biomarker disease BEFREE Prior findings have revealed vimentin-deficient mice are significantly protected from corneal fibrosis after alkali injury, which has implicated this IF protein as an important regulator of corneal fibrosis. 30590024 2019
CUI: C0558353
Disease: Tongue Carcinoma
Tongue Carcinoma
0.010 Biomarker disease BEFREE UCA1 knockdown significantly suppressed TGFβ1-induced tongue cancer cell invasion and EMT by decreasing vimentin and increasing E-cadherin. 30635938 2019
CUI: C0566602
Disease: Primary sclerosing cholangitis
Primary sclerosing cholangitis
0.010 Biomarker disease BEFREE The aim of this study is to evaluate the role of vimentin in the progression of biliary damage/liver fibrosis and whether there is a mesenchymal phenotype of cholangiocytes in the Mdr2<sup>-/-</sup> model of PSC. 31522982 2019
CUI: C0598935
Disease: Tumor Initiation
Tumor Initiation
0.010 AlteredExpression phenotype BEFREE The ZnAs@SiO<sub>2</sub> NPs also inhibited tumor spheroid formation <i>in vitro</i> and tumor initiation <i>in vivo</i> and induced significant changes in the expression of stemness markers (CD133, Sox-2, and Oct-4) and EMT markers (E-cadherin, Vimentin, and Slug) both <i>in vitro</i> and <i>in vivo.</i> These effects of ZnAs@SiO<sub>2</sub> that correlated with prognosis of HCC were mediated by the SHP-1/JAK2/STAT3 signaling. 31285768 2019
CUI: C0877015
Disease: Pelvic Organ Prolapse
Pelvic Organ Prolapse
0.010 AlteredExpression disease BEFREE The aim of this study was to explore the link between autophagy and collagen metabolism in patients with pelvic organ prolapse (POP) by detecting the expressions of autophagy factors, collagen, desmin, cytokeratin, and vimentin. 28786871 2019
CUI: C1135868
Disease: Gestational Trophoblastic Neoplasms
Gestational Trophoblastic Neoplasms
0.010 AlteredExpression group BEFREE Trophoblastic cells did not express vimentin, and the expression of E-cadherin was maintained in all cases, indicating the absence of EMT features in GTN. 30847562 2019
Myofibroma (morphologic abnormality)
0.010 Biomarker disease BEFREE Using a tissue microarray technique (TMA), cases of myofibroma (MF), of nodular fasciitis (NF), of desmoplastic fibroma (DF), and of myofibroblastic sarcoma (MS) from the Universidad Autónoma Metropolitana Xochimilco, and a Private Oral Pathology Service in Mexico City were stained with antibodies against alpha-smooth muscle actin (α-SMA), H-caldesmon, vimentin, desmin, β-catenin, CD34, anaplastic lymphoma protein kinase (ALK-1), and Ki-67. 30168888 2019
Stage IA Lung Adenocarcinoma AJCC v7
0.010 Biomarker disease BEFREE We conducted immunohistochemical analysis of the expression of the EMT markers E-cadherin and vimentin of specimens acquired from 183 consecutive patients with stage IA lung adenocarcinoma. 31103348 2019
CUI: C1368237
Disease: Solitary Myofibromatosis
Solitary Myofibromatosis
0.010 Biomarker disease BEFREE Using a tissue microarray technique (TMA), cases of myofibroma (MF), of nodular fasciitis (NF), of desmoplastic fibroma (DF), and of myofibroblastic sarcoma (MS) from the Universidad Autónoma Metropolitana Xochimilco, and a Private Oral Pathology Service in Mexico City were stained with antibodies against alpha-smooth muscle actin (α-SMA), H-caldesmon, vimentin, desmin, β-catenin, CD34, anaplastic lymphoma protein kinase (ALK-1), and Ki-67. 30168888 2019
CUI: C1397307
Disease: Cardiac fibrosis
Cardiac fibrosis
0.010 AlteredExpression disease BEFREE Flow cytometry analysis was performed to identify cardiac fibroblasts by examining vimentin, fibronectin (FN) and α-actin expression in human CFs. qRT-PCR and western blot assays were performed to confirm the expression of miR-32-5p, DUSP1 and cardiac fibrosis relevant proteins. 31438862 2019
CUI: C1519666
Disease: Tumor-Associated Vasculature
Tumor-Associated Vasculature
0.010 Biomarker disease BEFREE The native tropism of CPMV for cell-surface displayed vimentin and the enhanced permeability and retention effect allow them to preferentially extravasate from tumor neovasculature and efficiently penetrate tumors. 31004625 2019
CUI: C1704272
Disease: Benign Prostatic Hyperplasia
Benign Prostatic Hyperplasia
0.010 Biomarker disease BEFREE We isolated and cultured vimentin-positive prostate stromal cells obtained from BPH patients. 31730867 2019
CUI: C1709457
Disease: Papillary Thyroid Microcarcinoma
Papillary Thyroid Microcarcinoma
0.010 Biomarker disease BEFREE Immunohistochemical staining for Laminin Subunit Gamma 2 (LAMC2), CD59, E-cadherin, and vimentin showed that these markers of EMT were associated with progressive changes in E-margin PTMC-mETE(-), I-margin PTMC-mETE(-), and pPTMC-mETE(+). 31146263 2019
ASTHMA-RELATED TRAITS, SUSCEPTIBILITY TO, 1
0.010 AlteredExpression disease BEFREE Moreover, silencing ELFN1-AS1 significantly reduced the activation of extracellular signal-regulated protein kinase (Erk), up-regulated the protein expression of E-cadherin and down-regulated vimentin. 31814902 2019
CUI: C2020625
Disease: Group B Streptococcal Infection
Group B Streptococcal Infection
0.010 Biomarker disease BEFREE Vimentin null mice were protected from WT GBS infection and also exhibited less inflammatory cytokine production in brain tissue. 31181121 2019
Gastrointestinal Mixed Adenoneuroendocrine Carcinoma
0.010 Biomarker disease BEFREE The clinicopathological features of 13 consecutive cases of MANEC (6 gastric and 7 colorectal) were correlated with the IHC expression of the biomarkers E-cadherin, β-catenin, N-cadherin, vimentin, maspin, CD44 and S100. 31704155 2019
CUI: C3151140
Disease: PONTOCEREBELLAR HYPOPLASIA, TYPE 2D
PONTOCEREBELLAR HYPOPLASIA, TYPE 2D
0.010 Biomarker disease BEFREE An immunohistochemical method was used to detect MTDH expression and the epithelial-mesenchymal transition markers E-cadherin and vimentin in 66 cases of PCCA. 30988817 2019
CUI: C3203547
Disease: Axial spondyloarthritis
Axial spondyloarthritis
0.010 AlteredExpression disease BEFREE Metabolites of C-reactive protein and vimentin are associated with disease activity of axial spondyloarthritis. 30767876 2019
CUI: C3899281
Disease: Early Inflammatory Arthritis
Early Inflammatory Arthritis
0.010 Biomarker disease BEFREE The aim of the study was to evaluate the frequency of anti-mutated citrullinated vimentin antibodies (a-Sa), anti-citrullinated α-enolase peptide 1 antibodies (a-CEP-1), anti-filaggrin antibodies (AFAs), heterogeneous nuclear ribonucleoprotein compies/anti-RA33-antibodies (a-hnRNP/RA33), anti-carbamylated protein antibodies (a-CarP), and metalloproteinase (MMPs) activity in patients with early inflammatory arthritis (EIA). 30406565 2019
CUI: C4083008
Disease: Guillain-Barre Syndrome, Familial
Guillain-Barre Syndrome, Familial
0.010 Biomarker disease BEFREE Vimentin null mice were protected from WT GBS infection and also exhibited less inflammatory cytokine production in brain tissue. 31181121 2019
Non-squamous non-small cell lung cancer
0.010 Biomarker disease BEFREE The aim of the present study was to assess the expression of epithelial-mesenchymal transition biomarkers (E-cadherin and vimentin) and their potential significance as prognostic markers in patients with stage IIIB/IV non-squamous non-small cell lung cancer (NSCLC) enrolled in the INNOVATIONS trial, receiving treatment with either erlotinib/bevacizumab (EB) or cisplatin/gemcitabine/bevacizumab (PGB). 31186697 2019