VIM, vimentin, 7431

N. diseases: 644; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.100 AlteredExpression group BEFREE Analysis of several other kinds of epithelial carcinoma cell lines showed only rare examples of vimentin expression. 2472876 1989
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.100 Biomarker group BEFREE The cultured cells showed epithelial cell-like morphology and were positive immunohistochemically for vimentin as the original tumor. 2804914 1989
CUI: C0023467
Disease: Leukemia, Myelocytic, Acute
Leukemia, Myelocytic, Acute 		0.050 AlteredExpression disease BEFREE The expression of the myeloperoxidase (MPO) gene was studied, by means of Northern blot analysis in 14 cases of acute myeloid leukemia (AML), 11 cases of chronic myeloid leukemia (CML), and 6 cases of CML blast crisis, and in HL60 cells before and after induction of terminal differentiation with retinoic acid (RA), phorbol esters (TPA), or vitamin D. The expression of a panel of cell cycle-related genes, namely C-MYC, histone H3, ornithine decarboxylase, P53, vimentin, and calcyclin, was also studied in the same cell populations. 2542700 1989
CUI: C0023473
Disease: Myeloid Leukemia, Chronic
Myeloid Leukemia, Chronic 		0.010 AlteredExpression disease BEFREE The expression of the myeloperoxidase (MPO) gene was studied, by means of Northern blot analysis in 14 cases of acute myeloid leukemia (AML), 11 cases of chronic myeloid leukemia (CML), and 6 cases of CML blast crisis, and in HL60 cells before and after induction of terminal differentiation with retinoic acid (RA), phorbol esters (TPA), or vitamin D. The expression of a panel of cell cycle-related genes, namely C-MYC, histone H3, ornithine decarboxylase, P53, vimentin, and calcyclin, was also studied in the same cell populations. 2542700 1989
CUI: C0023487
Disease: Acute Promyelocytic Leukemia
Acute Promyelocytic Leukemia 		0.010 AlteredExpression disease BEFREE Expression of vimentin and nuclear lamins during the in vitro differentiation of human promyelocytic leukemia cells HL-60. 2697560 1989
CUI: C2745900
Disease: Promyelocytic leukemia
Promyelocytic leukemia 		0.010 AlteredExpression disease BEFREE Expression of vimentin and nuclear lamins during the in vitro differentiation of human promyelocytic leukemia cells HL-60. 2697560 1989
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.100 AlteredExpression group BEFREE Immunohistochemically, the original tumor had exhibited an intriguing potential for multidirectional differentiation with features of mesenchymal, epithelial and neural differentiation, evidenced by the co-expression of vimentin, cytokeratins and neurofilament proteins, respectively. 1688830 1990
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.100 Biomarker group BEFREE Immunostaining revealed that the tumors were positive for S-100 protein and vimentin and negative for glial fibrillary acidic protein, actin, and keratin. 2305928 1990
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.100 Biomarker group BEFREE These 3 vimentin-negative tumors were positive for cytokeratin and epithelial membrane antigen. 2298413 1990
CUI: C0029463
Disease: Osteosarcoma
Osteosarcoma 		0.060 Biomarker disease BEFREE Isolation of a human vimentin cDNA with a long 3'-noncoding region from a human osteosarcoma cell line (MG-63). 2323579 1990
CUI: C0585442
Disease: Osteosarcoma of bone
Osteosarcoma of bone 		0.060 Biomarker disease BEFREE Isolation of a human vimentin cDNA with a long 3'-noncoding region from a human osteosarcoma cell line (MG-63). 2323579 1990
CUI: C1332986
Disease: Childhood Osteosarcoma
Childhood Osteosarcoma 		0.060 Biomarker disease BEFREE Isolation of a human vimentin cDNA with a long 3'-noncoding region from a human osteosarcoma cell line (MG-63). 2323579 1990
CUI: C1850386
Disease: GIANT AXONAL NEUROPATHY 1
GIANT AXONAL NEUROPATHY 1 		0.030 GeneticVariation disease BEFREE Giant axonal neuropathy (GAN) is a disorder characterized pathologically by distal neurofilament-filled bulbous swellings in axons, and widespread collection of intermediate filaments, including masses of vimentin filaments in cultured skin fibroblasts. 2324766 1990
CUI: C0079744
Disease: Diffuse Large B-Cell Lymphoma
Diffuse Large B-Cell Lymphoma 		0.020 AlteredExpression disease BEFREE Induction of differentiation of the human histiocytic lymphoma cell line U937 in the absence of vimentin expression. 2292364 1990
CUI: C0020097
Disease: HTLV-I Infections
HTLV-I Infections 		0.010 AlteredExpression group BEFREE Our findings indicate that constitutive expression of the vimentin gene under the control of the Tax protein may be relevant in understanding the progression of the lymphoproliferative process associated with human T-cell leukemia virus type I infection. 2293664 1990
CUI: C0023418
Disease: leukemia
leukemia 		0.010 AlteredExpression disease BEFREE The induction of vimentin gene expression by sodium butyrate in human promonocytic leukemia U937 cells. 2328771 1990
CUI: C0023493
Disease: Adult T-Cell Lymphoma/Leukemia
Adult T-Cell Lymphoma/Leukemia 		0.010 AlteredExpression disease BEFREE Effect of human T-cell leukemia virus type I tax protein on activation of the human vimentin gene. 2293664 1990
CUI: C0024302
Disease: Reticulosarcoma
Reticulosarcoma 		0.010 AlteredExpression disease BEFREE Induction of differentiation of the human histiocytic lymphoma cell line U937 in the absence of vimentin expression. 2292364 1990
CUI: C0205944
Disease: Sarcoma, Epithelioid
Sarcoma, Epithelioid 		0.010 AlteredExpression disease BEFREE Multidirectional differentiation in a newly established human epithelioid sarcoma cell line (GRU-1) with co-expression of vimentin, cytokeratins and neurofilament proteins. 1688830 1990
CUI: C0279545
Disease: Adult Epithelioid Sarcoma
Adult Epithelioid Sarcoma 		0.010 AlteredExpression disease BEFREE Multidirectional differentiation in a newly established human epithelioid sarcoma cell line (GRU-1) with co-expression of vimentin, cytokeratins and neurofilament proteins. 1688830 1990
CUI: C0279989
Disease: Childhood Epithelioid Sarcoma
Childhood Epithelioid Sarcoma 		0.010 AlteredExpression disease BEFREE Multidirectional differentiation in a newly established human epithelioid sarcoma cell line (GRU-1) with co-expression of vimentin, cytokeratins and neurofilament proteins. 1688830 1990
CUI: C0334663
Disease: Histiocytic sarcoma
Histiocytic sarcoma 		0.010 AlteredExpression disease BEFREE Induction of differentiation of the human histiocytic lymphoma cell line U937 in the absence of vimentin expression. 2292364 1990
CUI: C1332977
Disease: Childhood Leukemia
Childhood Leukemia 		0.010 AlteredExpression disease BEFREE The induction of vimentin gene expression by sodium butyrate in human promonocytic leukemia U937 cells. 2328771 1990
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.400 AlteredExpression disease BEFREE We find that fibroblastoid, highly invasive, vimentin-expressing breast cancer cell lines do not express uvomorulin. 1793731 1991
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.400 AlteredExpression disease BEFREE We find that fibroblastoid, highly invasive, vimentin-expressing breast cancer cell lines do not express uvomorulin. 1793731 1991