Pharyngitis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
To clarify the relationship between STSS and pharyngitis in Japan, we examined the T serotypes of GAS strains isolated from clinical specimens of streptococcal infections (STSS, 951 isolates; pharyngitis, 16268 isolates) from 2005 to 2017.
|
31735631 |
2020 |
Pharyngitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
<i>Streptococcus pyogenes</i> (group A streptococcus [GAS]) is a serious human pathogen with the ability to colonize mucosal surfaces such as the nasopharynx and vaginal tract, often leading to infections such as pharyngitis and vulvovaginitis.
|
31239377 |
2019 |
Pharyngitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
<b>IMPORTANCE</b> The human bacterial pathogen <i>Streptococcus pyogenes</i> (group A streptococcus [GAS]) causes more than 600 million cases of pharyngitis annually worldwide, 15 million of which occur in the United States.
|
29104937 |
2019 |
Pharyngitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Based on our pragmatic trial, the routine use of this probiotic in the prevention of pharyngitis associated with GAS detection is not supported.
|
29189607 |
2018 |
Pharyngitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
A total of 135 GAS clinical strains were isolated from the tonsils of 116 pediatric patients with acute GAS pharyngitis between November, 2012 and April, 2014 in Saga, Japan.
|
30247119 |
2018 |
Pharyngitis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
<i>Streptococcus pyogenes</i> (Group A <i>Streptococcus</i>; GAS) commonly causes pharyngitis in children and adults, with severe invasive disease and immune sequelae being an infrequent consequence.
|
29868516 |
2018 |
Pharyngitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Streptococcus pyogenes (group A Streptococcus, GAS) is responsible for a variety of highly communicable infections, accounting for 5-15 and 20-30% of sore throat hospital visits in adults and children, respectively.
|
29967988 |
2018 |
Pharyngitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Streptococcus pyogenes (group A Streptococcus; GAS) causes clinical diseases, including pharyngitis, scarlet fever, impetigo, necrotizing fasciitis and streptococcal toxic shock syndrome.
|
28355251 |
2017 |
Pharyngitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
The case demonstrates that ARF can develop in the absence of GAS pharyngitis and highlights a need for further research into the role of pyoderma and non-Group A Streptococci infections in ARF pathogenesis.
|
28121967 |
2017 |
Pharyngitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Primary abscess of the iliopsoas muscle in children is uncommon, especially due to Streptococcus pyogenes (group A streptococcus: GAS), which causes a variety of diseases ranging from pharyngitis to invasive life-threatening infection.
|
27692341 |
2016 |
Pharyngitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
S. pyogenes (group A streptococcus [GAS]) causes pharyngitis ("strep throat"), necrotizing fasciitis, and other human infections.
|
26443457 |
2015 |
Pharyngitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
In this study, we investigate the role of zinc efflux in the pathogenesis of Streptococcus pyogenes (group A Streptococcus [GAS]), a human pathogen responsible for superficial infections, such as pharyngitis and impetigo, and severe invasive infections.
|
24449444 |
2014 |
Pharyngitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Rapid accurate detection of GAS in pharyngeal specimens from individuals suffering from pharyngitis aids in the management and selection of antibiotic therapy for these patients.
|
23447639 |
2013 |
Pharyngitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
This novel activity of NADase to block autophagic killing of GAS in pharyngeal cells may contribute to pharyngitis treatment failure, relapse, and chronic carriage.
|
23762025 |
2013 |
Pharyngitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Diseases caused by Streptococcus pyogenes (Group A streptococcus, GAS) range from superficial infections such as pharyngitis and impetigo to potentially fatal rheumatic heart disease and invasive disease.
|
23179674 |
2013 |
Pharyngitis
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
This in vivo genome-wide analysis of GAS gene expression in humans with pharyngitis evaluated global gene expression in terms of virulence factors.
|
21799202 |
2011 |
Pharyngitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Streptococcus pyogenes (group A streptococci; GAS) recovered from paediatric pharyngitis (101 isolates) and asymptomatic children (79 isolates) in the same geographical area and period, as well as isolates collected during an enhanced national surveillance programme for GAS invasive diseases (79 isolates), were screened for the incidence of the streptococcal pyrogenic exotoxin (spe) genes speA and speC, as well as the macrolide-resistance genes erm(B), erm(A) subclass erm(TR) and mef(A), and typed by emm sequencing.
|
16157543 |
2005 |
Pharyngitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
To provide new information about GAS host-pathogen interactions, we used real-time reverse transcription-PCR (RT-PCR) to analyze transcripts of 17 GAS genes in throat swab specimens taken from 18 pediatric patients with pharyngitis.
|
12654842 |
2003 |
Rheumatic Fever
|
0.050 |
Biomarker
|
disease |
BEFREE |
Our results highlight significant knowledge gaps in the understanding of rheumatic fever pathogenesis and suggest that a GAS vaccine candidate should offer broad coverage against a variety of GAS genetic variants in order to protect against this serious sequela.
|
31334754 |
2020 |
Streptococcal toxic shock syndrome
|
0.050 |
Biomarker
|
phenotype |
BEFREE |
Streptococcus pyogenes (group A streptococcus; GAS) is an important gram-positive human pathogen capable of causing diseases ranging from mild superficial skin and pharyngeal infections to more severe invasive diseases, including streptococcal toxic shock syndrome (STSS).
|
31735631 |
2020 |
Streptococcal toxic shock syndrome
|
0.050 |
Biomarker
|
phenotype |
BEFREE |
We report the case of an adult woman with lactational amenorrhea and GAS vulvovaginitis progressing to STSS.
|
31151810 |
2019 |
Rheumatic Fever
|
0.050 |
Biomarker
|
disease |
BEFREE |
The case demonstrates that ARF can develop in the absence of GAS pharyngitis and highlights a need for further research into the role of pyoderma and non-Group A Streptococci infections in ARF pathogenesis.
|
28121967 |
2017 |
Streptococcal toxic shock syndrome
|
0.050 |
Biomarker
|
phenotype |
BEFREE |
Streptococcus pyogenes (group A Streptococcus; GAS) causes clinical diseases, including pharyngitis, scarlet fever, impetigo, necrotizing fasciitis and streptococcal toxic shock syndrome.
|
28355251 |
2017 |
Streptococcal toxic shock syndrome
|
0.050 |
Biomarker
|
phenotype |
BEFREE |
Streptococcus pyogenes (group A Streptococcus; GAS) is a widespread human pathogen and causes streptococcal toxic shock syndrome (STSS).
|
27349341 |
2016 |
Rheumatic Fever
|
0.050 |
Biomarker
|
disease |
BEFREE |
For most etiologies, symptoms are self-limited and resolve without lasting effects; however, pharyngitis resulting from infection with Streptococcus pyogenes (a group A Streptococcus [GAS]) can be associated with serious sequelae, including acute rheumatic fever and acute glomerulonephritis.
|
23447639 |
2013 |