|
Mammary Neoplasms
|
0.320 |
AlteredExpression
|
group |
BEFREE |
We used 212 breast tumor samples and lower levels of ADAM33 were correlated with TNBC and basal-like markers.
|
28294120 |
2017 |
|
Mammary Neoplasms
|
0.320 |
AlteredExpression
|
group |
BEFREE |
First, we analysed ADAM33 expression in breast tumour cell lines by RT-PCR and western blotting.
|
19267929 |
2009 |
|
Mammary Neoplasms, Human
|
0.300 |
Biomarker
|
disease |
CTD_human |
Breast cancer is associated with methylation and expression of the a disintegrin and metalloproteinase domain 33 (ADAM33) gene affected by endocrine‑disrupting chemicals.
|
30226539 |
2018 |
|
Mammary Carcinoma, Human
|
0.300 |
Biomarker
|
disease |
CTD_human |
Breast cancer is associated with methylation and expression of the a disintegrin and metalloproteinase domain 33 (ADAM33) gene affected by endocrine‑disrupting chemicals.
|
30226539 |
2018 |
|
Stage IV Skin Melanoma
|
0.300 |
GeneticVariation
|
disease |
UNIPROT |
|
|
|
|
Asthma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Our results detected a significant association between ADAM33 T2, Q1, F + 1 and AA genotype of T + 1 polymorphisms and asthma risk in total population.
|
30791911 |
2019 |
|
Asthma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Many asthma susceptibility genes are linked to the immune system or encode enzymes like metalloproteases (e.g., ADAM-33) or serine proteases.
|
27561663 |
2019 |
|
Asthma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Strong LD was found among rs678881, rs2280089 and rs2853209, and haplotype GGT was distinctly associated with the risk of asthma in children (OR = 0.28, 95%CI = 0.13-0.57).ADAM33 rs678881 polymorphism is significantly correlated with increased susceptibility to asthma in Chinese Han children.
|
31626088 |
2019 |
|
Asthma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The ADAM33 rs528557/S2 and the VEGFA rs833069 SNPs were associated with Thai asthmatics, as well as with other populations worldwide.
|
31586488 |
2019 |
|
Asthma
|
0.100 |
Biomarker
|
disease |
BEFREE |
No association was found between SNPs of ADAM33 with the severity of asthma.
|
31719298 |
2019 |
|
Asthma
|
0.100 |
Biomarker
|
disease |
BEFREE |
The studied SNPs of ADAM33 appeared to be non-significant for asthma susceptibility in Northern and Central Punjabi population.
|
31423513 |
2019 |
|
Chronic Obstructive Airway Disease
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Association between F+1 polymorphism in a disintegrin and metalloprotease 33 (ADAM33) gene and chronic obstructive pulmonary disease susceptibility: An evidence-based meta-analysis.
|
31357020 |
2019 |
|
Childhood asthma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Strong LD was found among rs678881, rs2280089 and rs2853209, and haplotype GGT was distinctly associated with the risk of asthma in children (OR = 0.28, 95%CI = 0.13-0.57).ADAM33 rs678881 polymorphism is significantly correlated with increased susceptibility to asthma in Chinese Han children.
|
31626088 |
2019 |
|
Asthma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
IFN-γ may participate in airway remodeling in asthma by regulating the expression of the ADAM33 gene.
|
28346792 |
2018 |
|
Asthma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Association of ADAM33 gene polymorphisms with asthma in Mongolian and Han groups in Inner Mongolia.
|
30591802 |
2018 |
|
Asthma
|
0.100 |
PosttranslationalModification
|
disease |
BEFREE |
An ovalbumin-induced asthma model in rats was established for investigating the function of the silencing of ADAM33.
|
30450713 |
2018 |
|
Asthma
|
0.100 |
Biomarker
|
disease |
BEFREE |
IL4Rα and ADAM33 as genetic markers in asthma exacerbations and type-2 inflammatory endotype.
|
28326636 |
2017 |
|
Asthma
|
0.100 |
PosttranslationalModification
|
disease |
BEFREE |
Our work confirms that ASO-based gene silencing of ADAM33 is a useful tool for asthma research and therapy.
|
28918018 |
2017 |
|
Asthma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In agreement with some other studies in different populations, our results showed no association between frequency of genotype or alleles of both T1 and V4 SNPs in ADAM33 gene and predisposition to asthma in Azerbaijan population of Iran.
|
29149777 |
2017 |
|
Asthma
|
0.100 |
Biomarker
|
disease |
BEFREE |
ADAM33 F + 1, T2, and T1 polymorphisms showed significant associations with asthma risks in the overall and Caucasian children, Asian children, and Caucasian and Chinese children, respectively; however, these significant results were unstable in sensitivity analysis.
|
28285393 |
2017 |
|
Childhood asthma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
T1 polymorphism in a disintegrin and metalloproteinase 33 (ADAM33) gene may contribute to the risk of childhood asthma in Asians.
|
28285393 |
2017 |
|
Childhood asthma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
This meta-analysis suggested that ADAM33 polymorphisms rs2280091, rs2280090, rs2787094, rs44707 and rs528557 were significantly associated with a high risk of childhood asthma.
|
28876365 |
2017 |
|
Asthma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Our analysis suggests a likely role for ADAM33 and ADAM12 in the development of asthma in Egyptian children.
|
26553447 |
2016 |
|
Asthma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The current study aims to evaluate the association of ADAM33 gene polymorphisms with the risk of asthma in the Punjabi population of Pakistan.
|
26666372 |
2016 |
|
Asthma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
This interaction was notable in that rs910652 is located within 78 kilobases of ADAM33, which is one of the most well studied asthma susceptibility genes.
|
27387956 |
2016 |