|
Juvenile-Onset Still Disease
|
0.300 |
Biomarker
|
disease |
CTD_human |
Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets.
|
19565504 |
2009 |
|
Juvenile arthritis
|
0.300 |
Biomarker
|
disease |
CTD_human |
Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets.
|
19565504 |
2009 |
|
Juvenile psoriatic arthritis
|
0.300 |
Biomarker
|
disease |
CTD_human |
Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets.
|
19565504 |
2009 |
|
Polyarthritis, Juvenile, Rheumatoid Factor Negative
|
0.300 |
Biomarker
|
disease |
CTD_human |
Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets.
|
19565504 |
2009 |
|
Polyarthritis, Juvenile, Rheumatoid Factor Positive
|
0.300 |
Biomarker
|
disease |
CTD_human |
Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets.
|
19565504 |
2009 |
|
Glioma
|
0.110 |
GeneticVariation
|
disease |
BEFREE |
MAML2 rs7938889 and rs485842 polymorphisms were associated with the reduced risk of glioma (OR = 0.69, P=0.023; and OR = 0.81, P=0.032, respectively).
|
31652449 |
2019 |
|
Glioma
|
0.110 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors.
|
28346443 |
2017 |
|
Mucoepidermoid Carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Examination of the CRTC1/3-MAML2 fusion gene showed no relation between SRCC of primary unknown with metastasis to the cervical lymph node and MEC of the parotid gland.
|
30954307 |
2020 |
|
Intelligence
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.
|
31374203 |
2019 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.
|
31374203 |
2019 |
|
Mucoepidermoid Carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Salivary gland MEC are most frequently associated with CRTC1-MAML2 translocations.
|
30380176 |
2019 |
|
Mucoepidermoid Carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Bronchial Mucoepidermoid Carcinoma With the Classic MAML2 Gene Rearrangement in a 2-year-old Boy.
|
28492094 |
2019 |
|
Mucoepidermoid Carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Articles that assessed the association between the CRTC1-MAML2 translocation and survival of MEC patients were selected for the systematic review.
|
31661572 |
2019 |
|
Mucoepidermoid Carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Rearrangement of mastermind like transcriptional coactivator 2 (MAML2) (11q21) gene was shown to be present in tumor cells by fluorescence in situ hybridization, supporting the diagnosis of a low-grade Warthin-like mucoepidermoid carcinoma.
|
31177170 |
2019 |
|
Mucoepidermoid Carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Gefitinib represses JAK-STAT signaling activated by CRTC1-MAML2 fusion in mucoepidermoid carcinoma cells.
|
30605061 |
2019 |
|
Mucoepidermoid Carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
The aims of this study were to determine the prognostic significance of MEC grading systems and MAML2 rearrangement status.
|
31021855 |
2019 |
|
Mucoepidermoid Carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
CRTC1-MAML2 fusion is often detected in low- or intermediate-grade salivary mucoepidermoid carcinoma (MEC), and it is associated with a favorable clinical course.
|
31351495 |
2019 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
An excellent prognosis may be achieved without PORT in T1/2N0M0 mucoepidermoid carcinoma patients positive for CRTC1/3-MAML2 fusions when the tumors are completely resected without tumor spillage.
|
30475407 |
2018 |
|
Mucoepidermoid Carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We present 2 variants of MEC for which MAML2 studies were crucial in establishing a diagnosis: a previously undescribed ciliated variant, and the recently described Warthin-like variant.
|
28877061 |
2018 |
|
Mucoepidermoid Carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
CRTC1/3-MAML2 fusion gene is a characteristic molecular feature of MEC of the salivary gland.
|
30138216 |
2018 |
|
Mucoepidermoid Carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Tumor categories as described by the World Health Organization reflect, in part, a true genetic heterogeneity (e.g., translocations involving CRTC1 and CRTC3-MAML2 genes in mucoepidermoid carcinoma and MYB-NFIB fusion in adenoid cystic carcinoma).
|
28930752 |
2018 |
|
Mucoepidermoid Carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The CRTC1-MAML2 fusion gene resulting from a t(11;19)(q21;p13) translocation, is now known to be a feature of both low-grade and high-grade mucoepidermoid carcinomas associated with improved survival.
|
29076877 |
2018 |
|
Mucoepidermoid Carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
We found that LINC00473 transcription was significantly induced in human CRTC1-MAML2-positive MEC cell lines and primary MEC tumors, and was tightly correlated with the CRTC1-MAML2 RNA level.
|
29353885 |
2018 |
|
Mucoepidermoid Carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Analysis of MAML2 rearrangement can be used as a supportive evidence to distinguish central MEC from GOC.
|
29131467 |
2018 |
|
Adolescent idiopathic scoliosis
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.
|
30019117 |
2018 |