|
Diabetes Mellitus
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Adjustment for liver fat and triacylglycerols, adiponectin and C-reactive protein substantially attenuated associations between height and diabetes risk, particularly among women.
|
31501920 |
2019 |
|
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
BEFREE |
Although targeting adiponectin and its receptors has been useful for treating diabetes and other metabolic-related diseases in experimental studies, current drug development based on adiponectin/adiponectin receptors for clinical applications is scarce, and there is a lack of available clinical trial data.
|
25818192 |
2015 |
|
Diabetes Mellitus
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Although the region on chromosome 11 has been associated with obesity and diabetes-related traits in adult populations, this is the first observation of linkage in this region for adiponectin levels.
|
16894363 |
2007 |
|
Diabetes Mellitus
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Among human adiponectin mutations, G84R and G90S mutants, which are associated with diabetes and hypoadiponectinemia, did not form HMW multimers.
|
12878598 |
2003 |
|
Diabetes Mellitus
|
0.400 |
AlteredExpression
|
group |
BEFREE |
Analyses were performed in both models, i.e. adiponectin stimulated blastocysts (in vitro) and in blastocysts grown in vivo under increased adiponectin levels caused by a maternal diabetes mellitus.
|
28472298 |
2017 |
|
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
BEFREE |
As the rates of obesity and diabetes increase in African Americans and Hispanics, adiponectin and its functional SNPs may aid in breast cancer risk assessment.
|
23624817 |
2013 |
|
Diabetes Mellitus
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Association between ADIPOQ gene polymorphisms and the risk of new-onset diabetes mellitus after liver transplantation.
|
29291779 |
2017 |
|
Diabetes Mellitus
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Association between 276G/T adiponectin gene polymorphism and new-onset diabetes after kidney transplantation.
|
23985723 |
2013 |
|
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
BEFREE |
Association between carotid intima-media thickness and adiponectin in participants without diabetes or cardiovascular disease of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).
|
27550907 |
2017 |
|
Diabetes Mellitus
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Association between the adiponectin promoter rs266729 gene variant and oxidative stress in patients with diabetes mellitus.
|
19324915 |
2009 |
|
Diabetes Mellitus
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Association of adiponectin gene polymorphism rs266729 with type two diabetes mellitus in Iraqi population. A pilot study.
|
26051417 |
2015 |
|
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
BEFREE |
Association of adiponectin with cognitive function precedes overt diabetes in the Brazilian Longitudinal Study of Adult Health: ELSA.
|
30002734 |
2018 |
|
Diabetes Mellitus
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Association of genetic variants in RETN, NAMPT and ADIPOQ gene with glycemic, metabolic traits and diabetes risk in a Chinese population.
|
29101068 |
2018 |
|
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
CTD_human |
Association of hypoadiponectinemia with impaired vasoreactivity.
|
12860835 |
2003 |
|
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
BEFREE |
Associations between adiponectin, HR and HRV differed depending on diabetes status.
|
29195493 |
2017 |
|
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
BEFREE |
At Cox regression analysis the predictive ability of low serum adiponectin was confirmed also after adjustment for age, male gender and diabetes.
|
29305337 |
2018 |
|
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
BEFREE |
Baseline adiponectin concentration and clinical outcomes among patients with diabetes and recent acute coronary syndrome in the EXAMINE trial.
|
28195387 |
2017 |
|
Diabetes Mellitus
|
0.400 |
AlteredExpression
|
group |
BEFREE |
C1q tumour necrosis factor-related protein 9 and adiponectin were higher in diabetes mellitus with severe peripheral arterial disease than diabetes mellitus with mild and moderate peripheral arterial disease groups.
|
29543038 |
2018 |
|
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
BEFREE |
C1q/TNF-related protein 3 (CTRP3), a paralog of adiponectin, has been proposed to exert anti-apoptotic effects and to attenuate diabetes-related cardiac injuries.
|
29572383 |
2018 |
|
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
BEFREE |
Circulating adiponectin is known to correlate negatively with insulin resistance in patients with obesity and diabetes.
|
22161113 |
2012 |
|
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
BEFREE |
Circulating adiponectin concentration is inversely associated with glucose tolerance and insulin secretion in people with newly diagnosed diabetes.
|
27770592 |
2017 |
|
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
BEFREE |
Circulating concentrations of adiponectin are lower in patients with diabetes, cardiovascular disease, and several malignancies.
|
19906806 |
2010 |
|
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
BEFREE |
Combined association of maternal and paternal family history of diabetes with plasma leptin and adiponectin in overweight Hispanic children.
|
19183309 |
2008 |
|
Diabetes Mellitus
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Common Polymorphisms in the Adiponectin Gene ACDC Are Not Associated With Diabetes in Pima Indians.
|
15616040 |
2005 |
|
Diabetes Mellitus
|
0.400 |
Biomarker
|
group |
BEFREE |
Compared to controls, patients presented significantly lower levels of cholesterol, high-density lipoprotein cholesterol (HDLc), LDLc, oxLDL, and intermediate and small HDL and higher triglycerides, CRP, adiponectin, large HDL, very-low-density lipoprotein (VLDL), and intermediate-density lipoprotein- (IDL) B. Adiponectin levels correlated positively with large HDL and negatively with intermediate and small HDL, oxLDL/LDLc, and BMI; patients with DM (<i>n</i> = 17) and with DM+HT (<i>n</i> = 70), as compared to patients without DM or HT (<i>n</i> = 69) or only with HT (<i>n</i> = 38), presented significantly higher oxLDL, oxLDL/LDLc, and leptin and lower adiponectin.
|
30911344 |
2019 |