|
Acute pancreatitis
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
The mouse stress-induced protein (SIP) mRNA is activated in the pancreas with acute pancreatitis and in several cell lines in response to various stress agents.
|
12067065 |
2002 |
|
Acute pancreatitis
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
We report here that TP53INP1 expression is induced during experimental acute pancreatitis in p53-/- mice and in cisplatin-treated p53-/- mouse embryo fibroblasts (MEFs).
|
16044147 |
2005 |
|
Malignant neoplasm of stomach
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
The decreased expression of the TP53INP1 protein may reflect the malignant grade of gastric cancer and is regarded as an adverse prognostic factor.
|
16521180 |
2006 |
|
Stomach Carcinoma
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
The decreased expression of the TP53INP1 protein may reflect the malignant grade of gastric cancer and is regarded as an adverse prognostic factor.
|
16521180 |
2006 |
|
Stomach Neoplasms
|
0.020 |
Biomarker
|
group |
LHGDN |
Down-expression of tumor protein p53-induced nuclear protein 1 in human gastric cancer.
|
16521180 |
2006 |
|
Carcinoma, Ehrlich Tumor
|
0.010 |
Biomarker
|
disease |
BEFREE |
S100A6 and CacyBP/SIP - two proteins discovered in ehrlich ascites tumor cells that are potentially involved in the degradation of beta-catenin.
|
16340196 |
2006 |
|
Metabolic Syndrome X
|
0.200 |
Biomarker
|
disease |
MGD |
Colitis and colitis-associated cancer are exacerbated in mice deficient for tumor protein 53-induced nuclear protein 1.
|
17242209 |
2007 |
|
Tumor Cell Invasion
|
0.080 |
Biomarker
|
phenotype |
BEFREE |
Taken together, our results suggest that CacyBP/SIP may be a potential inhibitor of cell growth and invasion in the gastric cancer cell, at least in part through the effect on beta-catenin protein expression and transcriptional activation of Tcf/LEF.
|
18171983 |
2007 |
|
Carcinogenesis
|
0.060 |
AlteredExpression
|
phenotype |
BEFREE |
Taken together, our work showed that CacyBP/SIP, as a novel down-regulated gene in renal cell carcinoma, suppressed proliferation and tumorigenesis of renal cancer cells.
|
17400182 |
2007 |
|
Malignant neoplasm of stomach
|
0.030 |
Biomarker
|
disease |
BEFREE |
In the present study, we prepared CacyBP/SIP overexpressing and knockdown cell lines of gastric cancer.
|
18171983 |
2007 |
|
Stomach Carcinoma
|
0.030 |
Biomarker
|
disease |
BEFREE |
In the present study, we prepared CacyBP/SIP overexpressing and knockdown cell lines of gastric cancer.
|
18171983 |
2007 |
|
Renal Cell Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Taken together, our work showed that CacyBP/SIP, as a novel down-regulated gene in renal cell carcinoma, suppressed proliferation and tumorigenesis of renal cancer cells.
|
17400182 |
2007 |
|
Conventional (Clear Cell) Renal Cell Carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Taken together, our work showed that CacyBP/SIP, as a novel down-regulated gene in renal cell carcinoma, suppressed proliferation and tumorigenesis of renal cancer cells.
|
17400182 |
2007 |
|
Carcinogenesis
|
0.060 |
Biomarker
|
phenotype |
BEFREE |
CacyBP/SIP protein might play an important role in the process of pancreatic carcinogenesis and high-level CacyBP/SIP expression might be related to the malignant potential of pancreatic cancer.
|
18765951 |
2008 |
|
Pancreatic carcinoma
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
CacyBP/SIP protein might play an important role in the process of pancreatic carcinogenesis and high-level CacyBP/SIP expression might be related to the malignant potential of pancreatic cancer.
|
18765951 |
2008 |
|
Malignant neoplasm of pancreas
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
CacyBP/SIP protein might play an important role in the process of pancreatic carcinogenesis and high-level CacyBP/SIP expression might be related to the malignant potential of pancreatic cancer.
|
18765951 |
2008 |
|
Stomach Neoplasms
|
0.020 |
AlteredExpression
|
group |
LHGDN |
Difference of p53AIP1 mRNA expression in gastric mucosa between patients with gastric cancer and chronic gastritis infected with Helicobacter pylori.
|
18277906 |
2008 |
|
Gastritis
|
0.010 |
AlteredExpression
|
disease |
LHGDN |
Difference of p53AIP1 mRNA expression in gastric mucosa between patients with gastric cancer and chronic gastritis infected with Helicobacter pylori.
|
18277906 |
2008 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
After qRT-PCR confirmation, we followed up 8 genes (AKAP12, ARHGEF16, ARHGAP27, ENC1, PPP1R3C, PPP1R14C, RARRES1, and TP53INP1) by quantitative DNA methylation analysis using mass spectrometry of base-specific cleaved amplification products in panels of melanoma cell lines and fresh tumors.
|
18803327 |
2009 |
|
melanoma
|
0.020 |
AlteredExpression
|
disease |
BEFREE |
PPP1R3C, ENC1, RARRES1, and TP53INP1, showed reduced mRNA expression in 35-59% of the melanoma cell lines compared to melanocytes and which was correlated with a high proportion of promoter methylation (>40-60%).
|
18803327 |
2009 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.140 |
GeneticVariation
|
disease |
GWASCAT |
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
|
20581827 |
2010 |
|
Diabetes Mellitus, Non-Insulin-Dependent
|
0.140 |
GeneticVariation
|
disease |
GWASDB |
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.
|
20581827 |
2010 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
A comparative analysis of oncofetal fibronectin and tenascin-C incorporation in tumour vessels using human recombinant SIP format antibodies.
|
20237793 |
2010 |
|
Neoplasm Metastasis
|
0.080 |
AlteredExpression
|
phenotype |
BEFREE |
The up-regulation of CacyBP/SIP expression also was shown to increase recurrence and metastasis of breast cancer and to correlate with short overall survival rate.
|
20585948 |
2010 |
|
Malignant neoplasm of breast
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
Poor cellular differentiation, lymph node invasion, and clinicopathological staging in breast cancer were associated with CacyBP/SIP expression.
|
20585948 |
2010 |