KRAS, KRAS proto-oncogene, GTPase, 3845

N. diseases: 1213; N. variants: 54
Source: ALL
Variant DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Disease Class Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs112445441
rs112445441 		0.658 0.400 12 25245347 missense variant C/A;G;T snv
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms 		Neoplasms; Hemic and Lymphatic Diseases 0.010 1.000 1 2007 2007
dbSNP: rs112445441
rs112445441 		0.658 0.400 12 25245347 missense variant C/A;G;T snv
CUI: C4688318
Disease: Refractory Colorectal Carcinoma
Refractory Colorectal Carcinoma 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2010 2010
dbSNP: rs112445441
rs112445441 		0.658 0.400 12 25245347 missense variant C/A;G;T snv
CUI: C0079773
Disease: Lymphoma, T-Cell, Cutaneous
Lymphoma, T-Cell, Cutaneous 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases 0.010 1.000 1 2011 2011
dbSNP: rs112445441
rs112445441 		0.658 0.400 12 25245347 missense variant C/A;G;T snv
CUI: C2939419
Disease: Secondary Neoplasm
Secondary Neoplasm 		Pathological Conditions, Signs and Symptoms; Neoplasms 0.010 1.000 1 2009 2009
dbSNP: rs1137188
rs1137188 		1.000 0.080 12 25206418 3 prime UTR variant G/A snv 0.49
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2017 2017
dbSNP: rs1137188
rs1137188 		1.000 0.080 12 25206418 3 prime UTR variant G/A snv 0.49
CUI: C0027651
Disease: Neoplasms
Neoplasms 		Neoplasms 0.010 1.000 1 2017 2017
dbSNP: rs1137282
rs1137282 		0.851 0.120 12 25209843 missense variant A/G;T snv 0.19
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis 		Pathological Conditions, Signs and Symptoms; Neoplasms 0.010 1.000 1 2019 2019
dbSNP: rs1137282
rs1137282 		0.851 0.120 12 25209843 missense variant A/G;T snv 0.19
CUI: C3146257
Disease: Stage II Colon Cancer AJCC v7
Stage II Colon Cancer AJCC v7 		0.010 1.000 1 2018 2018
dbSNP: rs1137282
rs1137282 		0.851 0.120 12 25209843 missense variant A/G;T snv 0.19
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma 		Neoplasms; Endocrine System Diseases 0.010 1.000 1 2019 2019
dbSNP: rs1137282
rs1137282 		0.851 0.120 12 25209843 missense variant A/G;T snv 0.19
CUI: C0278479
Disease: Stage II Colon Cancer
Stage II Colon Cancer 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2018 2018
dbSNP: rs1137282
rs1137282 		0.851 0.120 12 25209843 missense variant A/G;T snv 0.19
CUI: C4525119
Disease: Stage II Colon Cancer AJCC v8
Stage II Colon Cancer AJCC v8 		0.010 1.000 1 2018 2018
dbSNP: rs121913236
rs121913236 		0.882 0.160 12 25245321 missense variant G/C;T snv
CUI: C0278987
Disease: Metastatic non-small cell lung cancer
Metastatic non-small cell lung cancer 		Neoplasms 0.010 1.000 1 2015 2015
dbSNP: rs121913236
rs121913236 		0.882 0.160 12 25245321 missense variant G/C;T snv
CUI: C3888018
Disease: Congenital Hyperinsulinism
Congenital Hyperinsulinism 		Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Digestive System Diseases; Nutritional and Metabolic Diseases 0.010 1.000 1 2016 2016
dbSNP: rs121913236
rs121913236 		0.882 0.160 12 25245321 missense variant G/C;T snv
CUI: C1864903
Disease: Hyperinsulinemic hypoglycemia
Hyperinsulinemic hypoglycemia 		Nutritional and Metabolic Diseases 0.010 1.000 1 2016 2016
dbSNP: rs121913238
rs121913238 		0.732 0.240 12 25227343 missense variant G/C;T snv
CUI: C4722085
Disease: Malignant neoplasm of colon and/or rectum
Malignant neoplasm of colon and/or rectum 		0.010 1.000 1 2013 2013
dbSNP: rs121913238
rs121913238 		0.732 0.240 12 25227343 missense variant G/C;T snv
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		Digestive System Diseases; Neoplasms 0.010 1.000 1 2013 2013
dbSNP: rs121913238
rs121913238 		0.732 0.240 12 25227343 missense variant G/C;T snv
CUI: C0079744
Disease: Diffuse Large B-Cell Lymphoma
Diffuse Large B-Cell Lymphoma 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases 0.010 1.000 1 2012 2012
dbSNP: rs121913238
rs121913238 		0.732 0.240 12 25227343 missense variant G/C;T snv
CUI: C0026948
Disease: Mycosis Fungoides
Mycosis Fungoides 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases 0.010 1.000 1 2011 2011
dbSNP: rs121913238
rs121913238 		0.732 0.240 12 25227343 missense variant G/C;T snv
CUI: C1368816
Disease: Sebaceous adenoma
Sebaceous adenoma 		Neoplasms 0.010 1.000 1 2016 2016
dbSNP: rs121913238
rs121913238 		0.732 0.240 12 25227343 missense variant G/C;T snv
CUI: C1261473
Disease: Sarcoma
Sarcoma 		Neoplasms 0.010 1.000 1 2013 2013
dbSNP: rs121913238
rs121913238 		0.732 0.240 12 25227343 missense variant G/C;T snv
CUI: C4551686
Disease: Malignant neoplasm of soft tissue
Malignant neoplasm of soft tissue 		Neoplasms 0.010 1.000 1 2013 2013
dbSNP: rs121913238
rs121913238 		0.732 0.240 12 25227343 missense variant G/C;T snv
CUI: C0238463
Disease: Papillary thyroid carcinoma
Papillary thyroid carcinoma 		Neoplasms; Endocrine System Diseases 0.010 1.000 1 2019 2019
dbSNP: rs121913238
rs121913238 		0.732 0.240 12 25227343 missense variant G/C;T snv
CUI: C0079773
Disease: Lymphoma, T-Cell, Cutaneous
Lymphoma, T-Cell, Cutaneous 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases 0.010 1.000 1 2011 2011
dbSNP: rs121913238
rs121913238 		0.732 0.240 12 25227343 missense variant G/C;T snv
CUI: C0036920
Disease: Sezary Syndrome
Sezary Syndrome 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases 0.010 1.000 1 2011 2011
dbSNP: rs121913238
rs121913238 		0.732 0.240 12 25227343 missense variant G/C;T snv
CUI: C1332201
Disease: Adult Diffuse Large B-Cell Lymphoma
Adult Diffuse Large B-Cell Lymphoma 		Neoplasms; Immune System Diseases; Hemic and Lymphatic Diseases 0.010 1.000 1 2012 2012