PPARGC1A, PPARG coactivator 1 alpha, 10891

N. diseases: 350; N. variants: 42
Disease: Obesity ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs8192678
rs8192678
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
CUI: C0028754
Disease:
Obesity 		0.080 GeneticVariation BEFREE The rs8192678 polymorphism was associated with obesity onset in adulthood. 29879371 2018
dbSNP: rs8192678
rs8192678
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
CUI: C0028754
Disease:
Obesity 		0.080 GeneticVariation BEFREE A single nucleotide variant of the PPARGC1A gene (rs8192678) is associated with T2D susceptibility, relative risk of obesity and insulin resistance, and lower indices of β cell function. 29186342 2018
dbSNP: rs8192678
rs8192678
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
CUI: C0028754
Disease:
Obesity 		0.080 GeneticVariation BEFREE Muscle peroxisome proliferator-activated receptor gamma co-activator 1 (PGC-1)α gene expression is influenced by the Gly482Ser gene polymorphism, which is a candidate genetic risk factor for diabetes mellitus and obesity. 27699582 2017
dbSNP: rs8192678
rs8192678
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
CUI: C0028754
Disease:
Obesity 		0.080 GeneticVariation BEFREE The aim of this study was to investigate the relationship between functional polymorphisms Gly482Ser in PPARGC1A and Pro12Ala in PPARG2 with the presence of obesity and metabolic risk factors. 26185753 2015
dbSNP: rs8192678
rs8192678
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
CUI: C0028754
Disease:
Obesity 		0.080 GeneticVariation BEFREE In this series, there was no association between G482S polymorphism and T2DM and obesity (body mass index >25 kg/m(2)). 19913841 2010
dbSNP: rs8192678
rs8192678
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
CUI: C0028754
Disease:
Obesity 		0.080 GeneticVariation BEFREE The Gly482Ser polymorphism in peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PPARGC1A) has been demonstrated to be associated with diabetes, obesity and hypertension, all of which are important risk factors for left ventricular diastolic dysfunction. 19077249 2008
dbSNP: rs8192678
rs8192678
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
CUI: C0028754
Disease:
Obesity 		0.080 GeneticVariation BEFREE Increased risk of obesity associated with the variant allele of the PPARGC1A Gly482Ser polymorphism in physically inactive elderly men. 16474966 2006
dbSNP: rs8192678
rs8192678
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
CUI: C0028754
Disease:
Obesity 		0.080 GeneticVariation BEFREE In this study, we examined whether this Gly482Ser polymorphism is associated with type 2 diabetes or obesity, or metabolic predictors of these diseases, in Pima Indians. 12606537 2003
dbSNP: rs17574213
rs17574213
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
CUI: C0028754
Disease:
Obesity 		0.010 GeneticVariation BEFREE The rs17574213 polymorphism was associated with obesity onset in children aged <1 years and 10-18 years. 29879371 2018