Disease: Chronic Obstructive Airway Disease ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs16969968
rs16969968
Entrez Id: 1138
Gene Symbol: CHRNA5
CHRNA5
CUI: C0024117
Disease:
Chronic Obstructive Airway Disease 		0.780 GeneticVariation BEFREE The FPRP test results were as follows: 1) when the prior probability was 0.001 and the OR was 1.5, ADAM33 rs612709, CHRNA3/5 rs1051730, CHRNA3/5 rs8034191, CHRNA3/5 rs16969968, and TGFB1 rs1800470 were truly associated with COPD risk (FPRP < 0.2); 2) when the prior probability was 0.000001 and the OR was 1.5, all the variants except TGFB1 rs1800470 remained noteworthy; and 3) when the probability was 0.000001 and the OR was 1.2, ADAM33 rs612709 and CHRNA3/5 rs1051730 remained true positives. 27323020 2016
dbSNP: rs16969968
rs16969968
Entrez Id: 1138
Gene Symbol: CHRNA5
CHRNA5
CUI: C0024117
Disease:
Chronic Obstructive Airway Disease 		0.780 GeneticVariation BEFREE The rs8040868 variant is in linkage disequilibrium with rs16969968 previously associated with COPD and altered expression of the CHRNA5 gene. 27835950 2016