|
rs110402
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Major Depressive Disorder
|
|
0.030 |
GeneticVariation |
BEFREE |
The association of the CRHR1 SNPs rs12944712, rs110402, and rs878886 with MDD was evaluated in 629 Brazilian adults of European descent recruited from the general population [180 (28.6%) with lifetime MDD].
|
27544317 |
2016 |
|
rs242939
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Major Depressive Disorder
|
|
0.030 |
GeneticVariation |
BEFREE |
In this study, we show a significant increase in the G-allele (rs242939) of the CRHR1 gene in the recurrent MDD group compared with the control group, and an overrepresentation of G-G-T hyplotype of the CRHR1 gene in recurrent MDD.
|
23529111 |
2013 |
|
rs242941
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Major Depressive Disorder
|
|
0.030 |
GeneticVariation |
BEFREE |
To investigate the possible relationship between genetic risk factors and depression in AD, we assessed genetic polymorphisms reported to be associated with depression (MAOA VNTR, ACE 288bp Insertion/ Deletion, 5HTTLPR, COMT Val158Met, BDNF Val66Met, TPH1 A218C, HTR2A T102C, P2RX7 Q460R, FKBP5 rs1360780 and CRHR1 rs242941) in a cross-sectional study on 246 AD patients with or without clinically significant major depressive disorder (MDD) according to DSM-IV.
|
23157339 |
2013 |
|
rs110402
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Major Depressive Disorder
|
|
0.030 |
GeneticVariation |
BEFREE |
Results from healthy controls and a preliminary sample of MDD participants show that CRHR1 single nucleotide polymorphism rs110402 moderates neural responses to emotional stimuli, suggesting a potential mechanism of vulnerability for the development of MDD.
|
22378896 |
2012 |
|
rs110402
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Major Depressive Disorder
|
|
0.030 |
GeneticVariation |
BEFREE |
The T-A haplotype consisting of rs7209436 and rs110402 in CRHR1 was positively associated with MDD.
|
22467522 |
2012 |
|
rs242939
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Major Depressive Disorder
|
|
0.030 |
GeneticVariation |
BEFREE |
CRHR1 gene (rs1876828, rs242939 and rs242941) and BDNF gene (rs6265) were identified in the samples of patients diagnosed with recurrent MDD and matched controls.
|
22194899 |
2011 |
|
rs242941
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Major Depressive Disorder
|
|
0.030 |
GeneticVariation |
BEFREE |
CRHR1 gene (rs1876828, rs242939 and rs242941) and BDNF gene (rs6265) were identified in the samples of patients diagnosed with recurrent MDD and matched controls.
|
22194899 |
2011 |
|
rs242939
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Major Depressive Disorder
|
|
0.030 |
GeneticVariation |
BEFREE |
In this study, we tested whether the polymorphisms of three sites (rs1876828, rs242939 and rs242941) in corticotropin-releasing hormone receptor1 (CRHR1) gene are related to 6 weeks fluoxetine antidepressant effect in 127 Han Chinese patients with MDD.
|
17258395 |
2007 |
|
rs242941
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Major Depressive Disorder
|
|
0.030 |
GeneticVariation |
BEFREE |
The results show that the rs242941 G/G genotype and homozygous GAG haplotype of the three single-nucleotide polymorphisms (SNPs) are associated with fluoxetine therapeutic response in MDD patients of high-anxiety (HA).
|
17258395 |
2007 |
|
rs12944712
|
CRHR1;LINC02210-CRHR1
|
Major Depressive Disorder
|
|
0.010 |
GeneticVariation |
BEFREE |
The sample was subdivided according to sex and smoking status RESULTS: Among nonsmokers, there were nominal associations between MDD and all tested SNPs (rs12944712, P=0.042; rs110402, P=0.031, and rs878886, P=0.040), regardless of sex.
|
27544317 |
2016 |
|
rs878886
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Major Depressive Disorder
|
|
0.010 |
GeneticVariation |
BEFREE |
The sample was subdivided according to sex and smoking status RESULTS: Among nonsmokers, there were nominal associations between MDD and all tested SNPs (rs12944712, P=0.042; rs110402, P=0.031, and rs878886</span>, P=0.040), regardless of sex.
|
27544317 |
2016 |
|
rs4792888
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Major Depressive Disorder
|
|
0.010 |
GeneticVariation |
BEFREE |
Only rs4792888 in CRHR1 showed modest evidence of association with duloxetine response in MDD (P=0.029 in GAD, P=0.054 in MDD).
|
22249355 |
2013 |
|
rs173365
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Major Depressive Disorder
|
|
0.010 |
GeneticVariation |
BEFREE |
The T-A-T-G-G haplotype consisting of rs7209436 and rs173365 in CRHR1 was positively associated with MDD.
|
22467522 |
2012 |
|
rs242924
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Major Depressive Disorder
|
|
0.010 |
GeneticVariation |
BEFREE |
The SNP rs110402 and rs242924 in the CRHR1 gene and the rs3779250 in the CRHR2 gene were associated with MDD.
|
22467522 |
2012 |
|
rs7209436
|
CRHR1;LINC02210-CRHR1
|
Major Depressive Disorder
|
|
0.010 |
GeneticVariation |
BEFREE |
The T-A haplotype consisting of rs7209436 and rs110402 in CRHR1 was positively associated with MDD.
|
22467522 |
2012 |
|
rs1876828
|
CRHR1;MAPT-AS1;LINC02210-CRHR1
|
Major Depressive Disorder
|
|
0.010 |
GeneticVariation |
BEFREE |
In this study, we tested whether the polymorphisms of three sites (rs1876828, rs242939 and rs242941) in corticotropin-releasing hormone receptor1 (CRHR1) gene are related to 6 weeks fluoxetine antidepressant effect in 127 Han Chinese patients with MDD.
|
17258395 |
2007 |