Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs7453920
rs7453920
Entrez Id: 3120
Gene Symbol: HLA-DQB2
HLA-DQB2
CUI: C0041296
Disease:
Tuberculosis 		0.010 GeneticVariation BEFREE These results suggested that the functional HLA-DQB2 rs7453920 G>A polymorphism may contribute to the genetic susceptibility to TB. 30600606 2019
dbSNP: rs7453920
rs7453920
Entrez Id: 3120
Gene Symbol: HLA-DQB2
HLA-DQB2
CUI: C0019196
Disease:
Hepatitis C 		0.010 GeneticVariation BEFREE The HLA-DQ rs7453920 and -DP rs9277535 mutations were significantly associated with HCV infection susceptibility and chronicity, respectively. 29212520 2017
dbSNP: rs7453920
rs7453920
Entrez Id: 3120
Gene Symbol: HLA-DQB2
HLA-DQB2
CUI: C0038013
Disease:
Ankylosing spondylitis 		0.010 GeneticVariation BEFREE This is the first study demonstrating the significant associations of SNP rs7453920 and the haplotypes in the HLA gene with the risk of AS in Southwest Chinese population. 27394003 2016
dbSNP: rs7453920
rs7453920
Entrez Id: 3120
Gene Symbol: HLA-DQB2
HLA-DQB2
CUI: C0151517
Disease:
Complete atrioventricular block 		0.010 GeneticVariation BEFREE Association of CHB with SNPs rs2856718 and rs7453920 remains significant even after stratification with rs3077 and rs9277535, indicating independent effect of HLA-DQ variants on CHB susceptibility (P-value of 1.52 × 10(-21)- 2.38 × 10(-30)). 21750111 2011
dbSNP: rs7769979
rs7769979
Entrez Id: 3120
Gene Symbol: HLA-DQB2
HLA-DQB2
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		0.010 GeneticVariation BEFREE Sequential removal of SLE-associated DRB1 haplotypes revealed independent effects due to variation within OR2H2 (extended class I, rs362521, p = 0.006), CREBL1 (class III, rs8283, p = 0.01), and DQB2 (class II, rs7769979, p = 0.003, and rs10947345, p = 0.0004). 19851445 2009
dbSNP: rs754855896
rs754855896
Entrez Id: 3120
Gene Symbol: HLA-DQB2
HLA-DQB2
CUI: C0011847
Disease:
Diabetes 		0.010 GeneticVariation BEFREE The aim of our study was to evaluate the frequency of the L-selectin gene T668C mutation (from thymine to cytosine at position 668) resulted in F206L an amino acid substitution in patients with overt diabetes and their unaffected first degree relatives in comparison to the unselected control population. 11064106 2000
dbSNP: rs754855896
rs754855896
Entrez Id: 3120
Gene Symbol: HLA-DQB2
HLA-DQB2
CUI: C0011849
Disease:
Diabetes Mellitus 		0.010 GeneticVariation BEFREE The aim of our study was to evaluate the frequency of the L-selectin gene T668C mutation (from thymine to cytosine at position 668) resulted in F206L an amino acid substitution in patients with overt diabetes and their unaffected first degree relatives in comparison to the unselected control population. 11064106 2000
dbSNP: rs754855896
rs754855896
Entrez Id: 3120
Gene Symbol: HLA-DQB2
HLA-DQB2
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		0.010 GeneticVariation BEFREE It was also shown that there is an association between T668C mutation and low HLA related risk of IDDM development, the highest frequency of F206L mutation in the EGF domain of L-selectin was observed in relatives with 'protective' HLA DQB1*0602 allele and nonDRB1*03-nonDRB1*04 haplotype, while in subjects with highest risk of IDDM haplotype the frequency of T668C mutation was similar to the controls. 11064106 2000
dbSNP: rs2071550
rs2071550
Entrez Id: 3120
Gene Symbol: HLA-DQB2
HLA-DQB2
CUI: C0428883
Disease:
Diastolic blood pressure 		0.700 GeneticVariation GWASCAT A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. 29455858 2018
dbSNP: rs7453920
rs7453920
Entrez Id: 3120
Gene Symbol: HLA-DQB2
HLA-DQB2
CUI: C0024141
Disease:
Lupus Erythematosus, Systemic 		A 0.700 GeneticVariation GWASDB GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region. 24871463 2014
dbSNP: rs7756516
rs7756516
Entrez Id: 3120
Gene Symbol: HLA-DQB2
HLA-DQB2
CUI: C0524909
Disease:
Hepatitis B, Chronic 		T 0.700 GeneticVariation GWASCAT A genome-wide association study on chronic HBV infection and its clinical progression in male Han-Taiwanese. 24940741 2014
dbSNP: rs2051549
rs2051549
Entrez Id: 3120
Gene Symbol: HLA-DQB2
HLA-DQB2
CUI: C0019163
Disease:
Hepatitis B 		0.700 GeneticVariation GWASDB A genome-wide association study identified new variants associated with the risk of chronic hepatitis B. 23760081 2013
dbSNP: rs2071551
rs2071551
Entrez Id: 3120
Gene Symbol: HLA-DQB2
HLA-DQB2
CUI: C0019163
Disease:
Hepatitis B 		0.700 GeneticVariation GWASDB A genome-wide association study identified new variants associated with the risk of chronic hepatitis B. 23760081 2013
dbSNP: rs762815
rs762815
Entrez Id: 3120
Gene Symbol: HLA-DQB2
HLA-DQB2
CUI: C0019163
Disease:
Hepatitis B 		0.700 GeneticVariation GWASDB A genome-wide association study identified new variants associated with the risk of chronic hepatitis B. 23760081 2013
dbSNP: rs7768538
rs7768538
Entrez Id: 3120
Gene Symbol: HLA-DQB2
HLA-DQB2
CUI: C0019163
Disease:
Hepatitis B 		0.700 GeneticVariation GWASDB A genome-wide association study identified new variants associated with the risk of chronic hepatitis B. 23760081 2013
dbSNP: rs9276583
rs9276583
Entrez Id: 3120
Gene Symbol: HLA-DQB2
HLA-DQB2
CUI: C0019163
Disease:
Hepatitis B 		0.700 GeneticVariation GWASDB A genome-wide association study identified new variants associated with the risk of chronic hepatitis B. 23760081 2013
dbSNP: rs11759423
rs11759423
Entrez Id: 3120
Gene Symbol: HLA-DQB2
HLA-DQB2
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.700 GeneticVariation GWASDB A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis. 21156761 2011
dbSNP: rs2301271
rs2301271
Entrez Id: 3120
Gene Symbol: HLA-DQB2
HLA-DQB2
CUI: C0019163
Disease:
Hepatitis B 		0.700 GeneticVariation GWASDB A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population. 21750111 2011
dbSNP: rs7774954
rs7774954
Entrez Id: 3120
Gene Symbol: HLA-DQB2
HLA-DQB2
CUI: C0036421
Disease:
Systemic Scleroderma 		0.700 GeneticVariation GWASDB Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus. 20383147 2010
dbSNP: rs6902723
rs6902723
Entrez Id: 3120
Gene Symbol: HLA-DQB2
HLA-DQB2
CUI: C0027404
Disease:
Narcolepsy 		0.700 GeneticVariation GWASDB Genome-wide association database developed in the Japanese Integrated Database Project. 19629137 2009
dbSNP: rs6903130
rs6903130
Entrez Id: 3120
Gene Symbol: HLA-DQB2
HLA-DQB2
CUI: C0027404
Disease:
Narcolepsy 		0.700 GeneticVariation GWASDB Genome-wide association database developed in the Japanese Integrated Database Project. 19629137 2009
dbSNP: rs7756516
rs7756516
Entrez Id: 3120
Gene Symbol: HLA-DQB2
HLA-DQB2
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.700 GeneticVariation GWASDB REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis. 19503088 2009
dbSNP: rs1573649
rs1573649
Entrez Id: 3120
Gene Symbol: HLA-DQB2
HLA-DQB2
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		0.700 GeneticVariation GWASDB A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene. 17632545 2007
dbSNP: rs2051549
rs2051549
Entrez Id: 3120
Gene Symbol: HLA-DQB2
HLA-DQB2
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		0.700 GeneticVariation GWASDB A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene. 17632545 2007
dbSNP: rs2051549
rs2051549
Entrez Id: 3120
Gene Symbol: HLA-DQB2
HLA-DQB2
CUI: C0026769
Disease:
Multiple Sclerosis 		0.700 GeneticVariation GWASDB Risk alleles for multiple sclerosis identified by a genomewide study. 17660530 2007