HLA-DQB2, major histocompatibility complex, class II, DQ beta 2, 3120
N. diseases: 91; N. variants: 16
Source: ALL
Variant | Gene | Disease | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||||
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0.700 | GeneticVariation | GWASDB | A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis. | 21156761 | 2011 | |||||||
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0.700 | GeneticVariation | GWASDB | A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene. | 17632545 | 2007 | |||||||
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G | 0.810 | GeneticVariation | GWASDB | GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region. | 24871463 | 2014 | ||||||
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0.810 | GeneticVariation | BEFREE | The most significant result of SLE GWAS meta-analysis concerned rs2051549 in the human leukocyte antigen (HLA) region (p = 3.36E-22). | 23053960 | 2012 | |||||||
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0.810 | GeneticVariation | GWASCAT | The most significant result of SLE GWAS meta-analysis concerned rs2051549 in the human leukocyte antigen (HLA) region (p = 3.36E-22). | 23053960 | 2012 | |||||||
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0.810 | GeneticVariation | GWASDB | The most significant result of SLE GWAS meta-analysis concerned rs2051549 in the human leukocyte antigen (HLA) region (p = 3.36E-22). | 23053960 | 2012 | |||||||
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0.700 | GeneticVariation | GWASDB | A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene. | 17632545 | 2007 | |||||||
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0.700 | GeneticVariation | GWASDB | A genome-wide association study identified new variants associated with the risk of chronic hepatitis B. | 23760081 | 2013 | |||||||
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0.700 | GeneticVariation | GWASDB | Risk alleles for multiple sclerosis identified by a genomewide study. | 17660530 | 2007 | |||||||
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0.700 | GeneticVariation | GWASDB | A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene. | 17632545 | 2007 | |||||||
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0.700 | GeneticVariation | GWASCAT | A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. | 29455858 | 2018 | |||||||
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0.700 | GeneticVariation | GWASDB | A genome-wide association study identified new variants associated with the risk of chronic hepatitis B. | 23760081 | 2013 | |||||||
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T | 0.800 | GeneticVariation | GWASCAT | Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. | 21408207 | 2011 | ||||||
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A | 0.800 | GeneticVariation | GWASDB | GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region. | 24871463 | 2014 | ||||||
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T | 0.800 | GeneticVariation | GWASDB | Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. | 21408207 | 2011 | ||||||
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0.700 | GeneticVariation | GWASDB | A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population. | 21750111 | 2011 | |||||||
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0.700 | GeneticVariation | GWASDB | A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene. | 17632545 | 2007 | |||||||
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0.700 | GeneticVariation | GWASDB | Genome-wide association database developed in the Japanese Integrated Database Project. | 19629137 | 2009 | |||||||
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0.700 | GeneticVariation | GWASDB | Risk alleles for multiple sclerosis identified by a genomewide study. | 17660530 | 2007 | |||||||
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0.700 | GeneticVariation | GWASDB | Risk alleles for multiple sclerosis identified by a genomewide study. | 17660530 | 2007 | |||||||
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0.700 | GeneticVariation | GWASDB | A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene. | 17632545 | 2007 | |||||||
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0.700 | GeneticVariation | GWASDB | Genome-wide association database developed in the Japanese Integrated Database Project. | 19629137 | 2009 | |||||||
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G | 0.880 | GeneticVariation | GWASDB | We found that rs9277535 (HLA-DPB1, P = 4.87×10(-14)), rs9276370 (HLA-DQA2, P = 1.9×10(-12)), rs7756516 and rs7453920 (HLA-DQB2, P = 1.48×10(-11) and P = 6.66×10(-15) respectively) were significantly associated with persistent HBV infection. | 24940741 | 2014 | ||||||
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0.880 | GeneticVariation | BEFREE | In addition, Uygurs have higher frequencies of HLA-DP/DQ protective alleles (72.5% for rs3077, 76.6% for rs9277535 and 26.8% for rs7453920) than Tibetans (51.7% for rs3077, 52.5% for rs9277535 and 18.5% for rs7453920)(all P < 0.05), and a lower prevalence of HBV infection as previously reported. | 25041342 | 2015 | |||||||
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G | 0.880 | GeneticVariation | GWASDB | New loci associated with chronic hepatitis B virus infection in Han Chinese. | 24162738 | 2013 |