ING1, inhibitor of growth family member 1, 3621

N. diseases: 99; N. variants: 5
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121909250
rs121909250
Entrez Id: 3621
Gene Symbol: ING1
ING1
CUI: C1168401
Disease:
Squamous cell carcinoma of the head and neck 		C 0.700 CausalMutation CLINVAR
dbSNP: rs121909251
rs121909251
Entrez Id: 3621
Gene Symbol: ING1
ING1
CUI: C1168401
Disease:
Squamous cell carcinoma of the head and neck 		G 0.700 CausalMutation CLINVAR
dbSNP: rs121909252
rs121909252
Entrez Id: 3621
Gene Symbol: ING1
ING1
CUI: C1168401
Disease:
Squamous cell carcinoma of the head and neck 		A 0.700 CausalMutation CLINVAR
dbSNP: rs140897205
rs140897205
Entrez Id: 3621
Gene Symbol: ING1
ING1
CUI: C0678222
Disease:
Breast Carcinoma 		0.010 GeneticVariation BEFREE The initial two stages, which involved up to 797 high-risk BC patients, 1504 consecutive BC cases, and 1081 healthy women, indicated a potentially BC-predisposing role for 6 candidates, i.e., USP39 c.*208G > C, PZP p.Arg680Ter, LEPREL1 p.Pro636Ser, SLIT3 p.Arg154Cys, CREB3 p.Lys157Glu, and ING1 p.Pro319Leu. 31754952 2020
dbSNP: rs140897205
rs140897205
Entrez Id: 3621
Gene Symbol: ING1
ING1
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.010 GeneticVariation BEFREE The initial two stages, which involved up to 797 high-risk BC patients, 1504 consecutive BC cases, and 1081 healthy women, indicated a potentially BC-predisposing role for 6 candidates, i.e., USP39 c.*208G > C, PZP p.Arg680Ter, LEPREL1 p.Pro636Ser, SLIT3 p.Arg154Cys, CREB3 p.Lys157Glu, and ING1 p.Pro319Leu. 31754952 2020
dbSNP: rs868443937
rs868443937
Entrez Id: 3621
Gene Symbol: ING1
ING1
CUI: C0025202
Disease:
melanoma 		0.010 GeneticVariation BEFREE We show that 20% of the melanoma primaries contained missense mutations in the SAP30-interacting domain and PHD finger motif of the ING1 gene with the R102L and N260S alterations observed more than once. 15201991 2004