LIPC, lipase C, hepatic type, 3990

N. diseases: 120; N. variants: 95
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1800588
rs1800588
Entrez Id: 3990;8854
Gene Symbol: LIPC;ALDH1A2
LIPC;ALDH1A2
CUI: C0010068
Disease:
Coronary heart disease
0.720 GeneticVariation BEFREE 557 men aged 45-74 with stable coronary artery disease and 560 paired controls were genotyped for rs1800588. 23874450 2013
dbSNP: rs1800588
rs1800588
Entrez Id: 3990;8854
Gene Symbol: LIPC;ALDH1A2
LIPC;ALDH1A2
CUI: C0010068
Disease:
Coronary heart disease
0.720 GeneticVariation GWASDB Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project. 21347282 2011
dbSNP: rs1800588
rs1800588
Entrez Id: 3990;8854
Gene Symbol: LIPC;ALDH1A2
LIPC;ALDH1A2
CUI: C0010068
Disease:
Coronary heart disease
0.720 GeneticVariation BEFREE The common C-480T polymorphism (rs1800588) of the hepatic lipase gene (LIPC) has been associated with high-density lipoprotein (HDL) cholesterol, atherosclerosis, and coronary artery disease. 19558527 2009
dbSNP: rs261332
rs261332
Entrez Id: 3990;8854;101928694
Gene Symbol: LIPC;ALDH1A2;LIPC-AS1
LIPC;ALDH1A2;LIPC-AS1
CUI: C0010068
Disease:
Coronary heart disease
0.700 GeneticVariation GWASCAT Pleiotropic Meta-Analyses of Longitudinal Studies Discover Novel Genetic Variants Associated with Age-Related Diseases. 27790247 2016
dbSNP: rs774232279
rs774232279
Entrez Id: 3990
Gene Symbol: LIPC
LIPC
CUI: C0010068
Disease:
Coronary heart disease
0.010 GeneticVariation BEFREE The multivariate model included 512 men with coronary artery disease from the REGRESS study who were completely genotyped for eight polymorphisms selected in the univariate procedure (ie, APOA1 G(-75)A, ABCA1 C(-477)T, ABCA1 G1051A, APOC3 T3206G, APOE Arg158Cys, LIPC C(-514)T, LPL Asn291Ser and LPL Ser447Stop). 15657615 2005