ARRB2, arrestin beta 2, 409

N. diseases: 119; N. variants: 6
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs8071086
rs8071086
Entrez Id: 409
Gene Symbol: ARRB2
ARRB2
CUI: C0023508
Disease:
White Blood Cell Count procedure 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs144830084
rs144830084
Entrez Id: 409
Gene Symbol: ARRB2
ARRB2
CUI: C2985280
Disease:
Blood Protein Measurement 		T 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488 2018
dbSNP: rs9913156
rs9913156
Entrez Id: 409
Gene Symbol: ARRB2
ARRB2
CUI: C0200635
Disease:
Lymphocyte Count measurement 		T 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs1045280
rs1045280
Entrez Id: 409
Gene Symbol: ARRB2
ARRB2
CUI: C0036341
Disease:
Schizophrenia 		0.020 GeneticVariation BEFREE The coding-synonymous polymorphism rs1045280 (Ser280Ser) in beta-arrestin 2 (ARRB2) gene is associated with tardive dyskinesia in Chinese patients with schizophrenia. 19049562 2008
dbSNP: rs1045280
rs1045280
Entrez Id: 409
Gene Symbol: ARRB2
ARRB2
CUI: C0036341
Disease:
Schizophrenia 		0.020 GeneticVariation BEFREE A possible association of 'tag single nucleotide polymorphisms (SNPs)' was found in METH use disorder (rs1045280: P(genotype) = 0.0118, P(allele) = 0.00351; rs2036657: P(allele) = 0.0431; rs4790694: P(genotype) = 0.0167, P(allele) = 0.0202), but no association was found with schizophrenia. 17233643 2007
dbSNP: rs4522461
rs4522461
Entrez Id: 409
Gene Symbol: ARRB2
ARRB2
CUI: C0040015
Disease:
Thrombasthenia 		0.010 GeneticVariation BEFREE We show that GG/GT patients for rs4522461 (n=534) and AA/AC patients for rs4790694 (n=244) have a lower response to AD than other genotype groups (HDRS score of 10.9 vs 8.0 after 6months, multivariate analysis: p=0.03; 12.2 vs 9.6, p=0.02, respectively). 29031912 2018
dbSNP: rs4522461
rs4522461
Entrez Id: 409
Gene Symbol: ARRB2
ARRB2
CUI: C0267026
Disease:
Actinic cheilitis 		0.010 GeneticVariation BEFREE We show that GG/GT patients for rs4522461 (n=534) and AA/AC patients for rs4790694 (n=244) have a lower response to AD than other genotype groups (HDRS score of 10.9 vs 8.0 after 6months, multivariate analysis: p=0.03; 12.2 vs 9.6, p=0.02, respectively). 29031912 2018
dbSNP: rs1045280
rs1045280
Entrez Id: 409
Gene Symbol: ARRB2
ARRB2
CUI: C0686347
Disease:
Tardive Dyskinesia 		0.010 GeneticVariation BEFREE To the best of our knowledge, this is the first study reporting a positive association between the SNP rs1045280 and TD in schizophrenic patients. 19049562 2008
dbSNP: rs1045280
rs1045280
Entrez Id: 409
Gene Symbol: ARRB2
ARRB2
CUI: C3714760
Disease:
Drug-induced tardive dyskinesia 		0.010 GeneticVariation BEFREE To the best of our knowledge, this is the first study reporting a positive association between the SNP rs1045280 and TD in schizophrenic patients. 19049562 2008
dbSNP: rs2036657
rs2036657
Entrez Id: 409
Gene Symbol: ARRB2
ARRB2
CUI: C0036341
Disease:
Schizophrenia 		0.010 GeneticVariation BEFREE A possible association of 'tag single nucleotide polymorphisms (SNPs)' was found in METH use disorder (rs1045280: P(genotype) = 0.0118, P(allele) = 0.00351; rs2036657: P(allele) = 0.0431; rs4790694: P(genotype) = 0.0167, P(allele) = 0.0202), but no association was found with schizophrenia. 17233643 2007