DisGeNET - a database of gene-disease associations

OPCML, opioid binding protein/cell adhesion molecule like, 4978

N. diseases: 75; N. variants: 20

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs10894604

Entrez Id:	4978
Gene Symbol:	OPCML

OPCML

CUI:	C0205682
Disease:

Waist-Hip Ratio

0.800

GeneticVariation

GWASDB

Genome-wide association of body fat distribution in African ancestry populations suggests new loci.

23966867

2013

dbSNP:

rs10894604

Entrez Id:	4978
Gene Symbol:	OPCML

OPCML

CUI:	C0205682
Disease:

Waist-Hip Ratio

0.800

GeneticVariation

GWASCAT

Genome-wide association of body fat distribution in African ancestry populations suggests new loci.

23966867

2013

dbSNP:

rs10894670

Entrez Id:	4978
Gene Symbol:	OPCML

OPCML

CUI:	C1305855
Disease:

Body mass index

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs2105808

Entrez Id:	4978
Gene Symbol:	OPCML

OPCML

CUI:	C1305855
Disease:

Body mass index

0.700

GeneticVariation

GWASCAT

Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.

30239722

2019

dbSNP:

rs4936175

Entrez Id:	4978
Gene Symbol:	OPCML

OPCML

CUI:	C1305855
Disease:

Body mass index

0.700

GeneticVariation

GWASCAT

Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

30595370

2019

dbSNP:

rs7124348

Entrez Id:	4978
Gene Symbol:	OPCML

OPCML

CUI:	C0037369
Disease:

Smoking

0.700

GeneticVariation

GWASCAT

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.

30643258

2019

dbSNP:

rs78058594

Entrez Id:	4978
Gene Symbol:	OPCML

OPCML

CUI:	C0037369
Disease:

Smoking

0.700

GeneticVariation

GWASCAT

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.

30643258

2019

dbSNP:

rs2221540

Entrez Id:	4978
Gene Symbol:	OPCML

OPCML

CUI:	C0041696
Disease:

Unipolar Depression

0.700

GeneticVariation

GWASCAT

Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder.

30571770

2018

dbSNP:

rs2221540

Entrez Id:	4978
Gene Symbol:	OPCML

OPCML

CUI:	C1269683
Disease:

Major Depressive Disorder

0.700

GeneticVariation

GWASCAT

Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder.

30571770

2018

dbSNP:

rs2602813

Entrez Id:	4978
Gene Symbol:	OPCML

OPCML

CUI:	C1837461
Disease:

SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3

0.700

GeneticVariation

GWASCAT

The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.

30019117

2018

dbSNP:

rs2602813

Entrez Id:	4978
Gene Symbol:	OPCML

OPCML

CUI:	C0410702
Disease:

Adolescent idiopathic scoliosis

0.700

GeneticVariation

GWASCAT

The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.

30019117

2018

dbSNP:

rs34814382

Entrez Id:	4978
Gene Symbol:	OPCML

OPCML

CUI:	C0596887
Disease:

mathematical ability

0.700

GeneticVariation

GWASCAT

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.

30038396

2018

dbSNP:

rs34814382

Entrez Id:	4978
Gene Symbol:	OPCML

OPCML

CUI:	C0596887
Disease:

mathematical ability

0.700

GeneticVariation

GWASCAT

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.

30038396

2018

dbSNP:

rs55983503

Entrez Id:	4978
Gene Symbol:	OPCML

OPCML

CUI:	C4317009
Disease:

Diverticular Diseases

0.700

GeneticVariation

GWASCAT

Genome-wide association analyses identify 39 new susceptibility loci for diverticular disease.

30177863

2018

dbSNP:

rs7938407

Entrez Id:	4978
Gene Symbol:	OPCML

OPCML

CUI:	C0596887
Disease:

mathematical ability

0.700

GeneticVariation

GWASCAT

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.

30038396

2018

dbSNP:

rs7938407

Entrez Id:	4978
Gene Symbol:	OPCML

OPCML

CUI:	C0596887
Disease:

mathematical ability

0.700

GeneticVariation

GWASCAT

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.

30038396

2018

dbSNP:

rs2917569

Entrez Id:	4978
Gene Symbol:	OPCML

OPCML

CUI:	C0036341
Disease:

Schizophrenia

0.700

GeneticVariation

GWASCAT

Genome-wide association study of schizophrenia in Ashkenazi Jews.

26198764

2015

dbSNP:

rs7104871

Entrez Id:	4978
Gene Symbol:	OPCML

OPCML

CUI:	C0871470
Disease:

Systolic Pressure

0.700

GeneticVariation

GWASCAT

Gene-smoking interactions identify several novel blood pressure loci in the Framingham Heart Study.

25189868

2015

dbSNP:

rs7117082

Entrez Id:	4978
Gene Symbol:	OPCML

OPCML

CUI:	C1862939
Disease:

AMYOTROPHIC LATERAL SCLEROSIS 1

0.700

GeneticVariation

GWASCAT

Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations.

24529757

2014

dbSNP:

rs7117082

Entrez Id:	4978
Gene Symbol:	OPCML

OPCML

CUI:	C3542025
Disease:

AMYOTROPHIC LATERAL SCLEROSIS 1, AUTOSOMAL RECESSIVE

0.700

GeneticVariation

GWASCAT

Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations.

24529757

2014

dbSNP:

rs7117082

Entrez Id:	4978
Gene Symbol:	OPCML

OPCML

CUI:	C1842675
Disease:

AMYOTROPHIC LATERAL SCLEROSIS 6 (disorder)

0.700

GeneticVariation

GWASCAT

Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations.

24529757

2014

dbSNP:

rs7117082

Entrez Id:	4978
Gene Symbol:	OPCML

OPCML

CUI:	C1862941
Disease:

Amyotrophic Lateral Sclerosis, Sporadic

0.700

GeneticVariation

GWASCAT

Genome-wide association study combining pathway analysis for typical sporadic amyotrophic lateral sclerosis in Chinese Han populations.

24529757

2014

dbSNP:

rs137852691

Entrez Id:	4978
Gene Symbol:	OPCML

OPCML

CUI:	C1140680
Disease:

Malignant neoplasm of ovary

0.700

GeneticVariation

UNIPROT

NSGC practice guideline: risk assessment and genetic counseling for hereditary breast and ovarian cancer.

23188549

2013

dbSNP:

rs137852691

Entrez Id:	4978
Gene Symbol:	OPCML

OPCML

CUI:	C1140680
Disease:

Malignant neoplasm of ovary

0.700

GeneticVariation

UNIPROT

Screening for ovarian cancer: U.S. Preventive Services Task Force reaffirmation recommendation statement.

22964825

2012

dbSNP:

rs7104890

Entrez Id:	4978
Gene Symbol:	OPCML

OPCML

CUI:	C0523465
Disease:

Serum albumin measurement

0.700

GeneticVariation

GWASDB

Genome-wide association study identifies multiple loci influencing human serum metabolite levels.

22286219

2012