BCL2, BCL2 apoptosis regulator, 596

N. diseases: 1456; N. variants: 27
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4940576
rs4940576
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C1837461
Disease:
SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3 		T 0.700 GeneticVariation GWASCAT Genome-wide association study identifies novel susceptible loci and highlights Wnt/beta-catenin pathway in the development of adolescent idiopathic scoliosis. 28334814 2017
dbSNP: rs7226979
rs7226979
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0002170
Disease:
Alopecia 		T 0.700 GeneticVariation GWASCAT Genetic prediction of male pattern baldness. 28196072 2017
dbSNP: rs12454712
rs12454712
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C1305855
Disease:
Body mass index 		T 0.700 GeneticVariation GWASCAT Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci. 27416945 2016
dbSNP: rs12454712
rs12454712
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C4049919
Disease:
Insulin Sensitivity Measurement 		T 0.700 GeneticVariation GWASCAT Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci. 27416945 2016
dbSNP: rs12454712
rs12454712
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0206161
Disease:
Reticulocyte count (procedure) 		C 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs17758695
rs17758695
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0750880
Disease:
Monocyte count result 		T 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs17758695
rs17758695
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0200638
Disease:
Eosinophil count procedure 		T 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs17758695
rs17758695
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0200641
Disease:
Blood basophil count (lab test) 		T 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs17758695
rs17758695
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0200665
Disease:
Platelet mean volume determination (procedure) 		T 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs17758695
rs17758695
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0032181
Disease:
Platelet Count measurement 		T 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs17758695
rs17758695
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C1261502
Disease:
Finding of Mean Corpuscular Hemoglobin 		T 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs17758695
rs17758695
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0014772
Disease:
Red Blood Cell Count measurement 		T 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs17758695
rs17758695
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0200637
Disease:
Monocyte count procedure 		T 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs17758695
rs17758695
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0524587
Disease:
Mean Corpuscular Volume (result) 		T 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs187971642
rs187971642
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0200635
Disease:
Lymphocyte Count measurement 		C 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs4987856
rs4987856
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0855095
Disease:
Small Lymphocytic Lymphoma 		C 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia. 26956414 2016
dbSNP: rs4940576
rs4940576
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C1837461
Disease:
SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3 		T 0.700 GeneticVariation GWASCAT Genome-wide association study identifies new susceptibility loci for adolescent idiopathic scoliosis in Chinese girls. 26394188 2015
dbSNP: rs4940576
rs4940576
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0410702
Disease:
Adolescent idiopathic scoliosis 		T 0.700 GeneticVariation GWASCAT Genome-wide association study identifies new susceptibility loci for adolescent idiopathic scoliosis in Chinese girls. 26394188 2015
dbSNP: rs4987852
rs4987852
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0855095
Disease:
Small Lymphocytic Lymphoma 		0.700 GeneticVariation GWASCAT Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia. 23770605 2013
dbSNP: rs4987855
rs4987855
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0855095
Disease:
Small Lymphocytic Lymphoma 		G 0.700 GeneticVariation GWASCAT Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia. 23770605 2013
dbSNP: rs4987867
rs4987867
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0428472
Disease:
Serum HDL cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs4987867
rs4987867
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0202236
Disease:
Triglycerides measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs4987867
rs4987867
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0392885
Disease:
High density lipoprotein measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622 2012
dbSNP: rs2279115
rs2279115
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0006826
Disease:
Malignant Neoplasms 		0.060 GeneticVariation BEFREE A functional single-nucleotide polymorphism (c.-938C>A, rs2279115) in the inhibitory P2 BCL2 gene promoter has been associated with clinical outcomes in various types of cancer. 28396899 2017
dbSNP: rs2279115
rs2279115
Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0006826
Disease:
Malignant Neoplasms 		0.060 GeneticVariation BEFREE Simultaneously, rs2279115 was correlated with a significantly higher risk of cancer prognosis in Asia but not in Caucasian. 28445963 2017