BACH2, BTB domain and CNC homolog 2, 60468

N. diseases: 130; N. variants: 33
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs72928038
rs72928038
Entrez Id: 60468
Gene Symbol: BACH2
BACH2
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.810 GeneticVariation GWASCAT Functional implications of disease-specific variants in loci jointly associated with coeliac disease and rheumatoid arthritis. 26546613 2016
dbSNP: rs72928038
rs72928038
Entrez Id: 60468
Gene Symbol: BACH2
BACH2
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.810 GeneticVariation BEFREE One SNP, rs72928038, mapping to an intron of BACH2, achieved genome-wide significance in the meta-analysis (P = 1.2 × 10(-8), OR 1.12), and a second SNP, rs911263, mapping to an intron of RAD51B, was significantly associated in the anti-CCP-positive RA subgroup (P = 4 × 10(-8), OR 0.89), confirming that both are RA susceptibility loci. 24022229 2013
dbSNP: rs72928038
rs72928038
Entrez Id: 60468
Gene Symbol: BACH2
BACH2
CUI: C0003873
Disease:
Rheumatoid Arthritis 		0.810 GeneticVariation GWASDB High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596 2012
dbSNP: rs72928038
rs72928038
Entrez Id: 60468
Gene Symbol: BACH2
BACH2
CUI: C0003873
Disease:
Rheumatoid Arthritis 		A 0.810 GeneticVariation GWASCAT High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596 2012
dbSNP: rs1847472
rs1847472
Entrez Id: 60468
Gene Symbol: BACH2
BACH2
CUI: C0010346
Disease:
Crohn Disease 		0.800 GeneticVariation GWASCAT Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. 28067908 2017
dbSNP: rs1847472
rs1847472
Entrez Id: 60468
Gene Symbol: BACH2
BACH2
CUI: C0021390
Disease:
Inflammatory Bowel Diseases 		0.800 GeneticVariation GWASCAT Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. 28067908 2017
dbSNP: rs1847472
rs1847472
Entrez Id: 60468
Gene Symbol: BACH2
BACH2
CUI: C0010346
Disease:
Crohn Disease 		0.800 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007 2016
dbSNP: rs1847472
rs1847472
Entrez Id: 60468
Gene Symbol: BACH2
BACH2
CUI: C0010346
Disease:
Crohn Disease 		C 0.800 GeneticVariation GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919 2015
dbSNP: rs1847472
rs1847472
Entrez Id: 60468
Gene Symbol: BACH2
BACH2
CUI: C0021390
Disease:
Inflammatory Bowel Diseases 		C 0.800 GeneticVariation GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919 2015
dbSNP: rs2474619
rs2474619
Entrez Id: 60468
Gene Symbol: BACH2
BACH2
CUI: C0007570
Disease:
Celiac Disease 		0.800 GeneticVariation GWASCAT Genome-wide association study of celiac disease in North America confirms FRMD4B as new celiac locus. 24999842 2014
dbSNP: rs2474619
rs2474619
Entrez Id: 60468
Gene Symbol: BACH2
BACH2
CUI: C0007570
Disease:
Celiac Disease 		0.800 GeneticVariation GWASDB Genome-wide association study of celiac disease in North America confirms FRMD4B as new celiac locus. 24999842 2014
dbSNP: rs1847472
rs1847472
Entrez Id: 60468
Gene Symbol: BACH2
BACH2
CUI: C0021390
Disease:
Inflammatory Bowel Diseases 		C 0.800 GeneticVariation GWASCAT Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. 23128233 2012
dbSNP: rs1847472
rs1847472
Entrez Id: 60468
Gene Symbol: BACH2
BACH2
CUI: C0021390
Disease:
Inflammatory Bowel Diseases 		C 0.800 GeneticVariation GWASDB Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. 23128233 2012
dbSNP: rs3757247
rs3757247
Entrez Id: 60468
Gene Symbol: BACH2
BACH2
CUI: C0042900
Disease:
Vitiligo 		A 0.800 GeneticVariation GWASCAT Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo. 22561518 2012
dbSNP: rs3757247
rs3757247
Entrez Id: 60468
Gene Symbol: BACH2
BACH2
CUI: C0042900
Disease:
Vitiligo 		A 0.800 GeneticVariation GWASDB Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo. 22561518 2012
dbSNP: rs7753008
rs7753008
Entrez Id: 60468
Gene Symbol: BACH2
BACH2
CUI: C0007570
Disease:
Celiac Disease 		0.800 GeneticVariation GWASDB High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596 2012
dbSNP: rs11755527
rs11755527
Entrez Id: 60468
Gene Symbol: BACH2
BACH2
CUI: C0011854
Disease:
Diabetes Mellitus, Insulin-Dependent 		G 0.800 GeneticVariation GWASCAT Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases. 21829393 2011
dbSNP: rs12212193
rs12212193
Entrez Id: 60468
Gene Symbol: BACH2
BACH2
CUI: C0026769
Disease:
Multiple Sclerosis 		G 0.800 GeneticVariation GWASCAT Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. 21833088 2011
dbSNP: rs12212193
rs12212193
Entrez Id: 60468
Gene Symbol: BACH2
BACH2
CUI: C0026769
Disease:
Multiple Sclerosis 		G 0.800 GeneticVariation GWASDB Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. 21833088 2011
dbSNP: rs7753008
rs7753008
Entrez Id: 60468
Gene Symbol: BACH2
BACH2
CUI: C0007570
Disease:
Celiac Disease 		C 0.800 GeneticVariation GWASCAT Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease. 22057235 2011
dbSNP: rs7753008
rs7753008
Entrez Id: 60468
Gene Symbol: BACH2
BACH2
CUI: C0007570
Disease:
Celiac Disease 		0.800 GeneticVariation GWASDB Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease. 22057235 2011
dbSNP: rs10806425
rs10806425
Entrez Id: 60468
Gene Symbol: BACH2
BACH2
CUI: C0007570
Disease:
Celiac Disease 		A 0.800 GeneticVariation GWASDB Multiple common variants for celiac disease influencing immune gene expression. 20190752 2010
dbSNP: rs10806425
rs10806425
Entrez Id: 60468
Gene Symbol: BACH2
BACH2
CUI: C0007570
Disease:
Celiac Disease 		A 0.800 GeneticVariation GWASCAT Multiple common variants for celiac disease influencing immune gene expression. 20190752 2010
dbSNP: rs1847472
rs1847472
Entrez Id: 60468
Gene Symbol: BACH2
BACH2
CUI: C0010346
Disease:
Crohn Disease 		G 0.800 GeneticVariation GWASCAT Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. 21102463 2010
dbSNP: rs1847472
rs1847472
Entrez Id: 60468
Gene Symbol: BACH2
BACH2
CUI: C0010346
Disease:
Crohn Disease 		G 0.800 GeneticVariation GWASDB Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. 21102463 2010