TNMD, tenomodulin, 64102

N. diseases: 86; N. variants: 4
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs5966709
rs5966709
Entrez Id: 64102
Gene Symbol: TNMD
TNMD
CUI: C0002395
Disease:
Alzheimer's Disease
0.010 GeneticVariation BEFREE Among the ε4-allele carriers, the women with rs5966709-TT genotype had smaller risk for having AD than those with other genotypes (odds ratio 0.47, p=0.019, false discovery rate 10.4%). 19524323 2011
dbSNP: rs1155974
rs1155974
Entrez Id: 64102
Gene Symbol: TNMD
TNMD
CUI: C0242383
Disease:
Age related macular degeneration
0.010 GeneticVariation BEFREE In comparison to women with other genotypes, the women who were homozygous for the minor allele (genotypes rs1155974-TT or rs2073163-CC) had 2.6 fold (p=0.021) or 1.9 fold (p=0.067) risk for having AMD, respectively. 19381347 2009
dbSNP: rs2073163
rs2073163
Entrez Id: 64102
Gene Symbol: TNMD
TNMD
CUI: C0242383
Disease:
Age related macular degeneration
0.010 GeneticVariation BEFREE Three markers, rs1155974, rs2073163, and rs7890586, were associated with a risk of AMD in women. 19381347 2009
dbSNP: rs1155974
rs1155974
Entrez Id: 64102
Gene Symbol: TNMD
TNMD
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
0.010 GeneticVariation BEFREE The risk of developing T2D was approximately 2-fold in individuals with genotypes associated with higher 2-hour plasma glucose levels; the hazard ratios were 2.192 (p = 0.025) for rs2073162-A, 2.191 (p = 0.027) for rs2073163-C, and 1.998 (p = 0.054) for rs1155974-T. 17495183 2007
dbSNP: rs2073162
rs2073162
Entrez Id: 64102
Gene Symbol: TNMD
TNMD
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
0.010 GeneticVariation BEFREE The same two markers together with rs2073162 associated with the conversion of IGT to T2D in men. 17495183 2007
dbSNP: rs2073162
rs2073162
Entrez Id: 64102
Gene Symbol: TNMD
TNMD
CUI: C0271650
Disease:
Impaired glucose tolerance
0.010 GeneticVariation BEFREE The same two markers together with rs2073162 associated with the conversion of IGT to T2D in men. 17495183 2007
dbSNP: rs2073163
rs2073163
Entrez Id: 64102
Gene Symbol: TNMD
TNMD
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
0.010 GeneticVariation BEFREE The risk of developing T2D was approximately 2-fold in individuals with genotypes associated with higher 2-hour plasma glucose levels; the hazard ratios were 2.192 (p = 0.025) for rs2073162-A, 2.191 (p = 0.027) for rs2073163-C, and 1.998 (p = 0.054) for rs1155974-T. 17495183 2007