TNMD, tenomodulin, 64102

N. diseases: 86; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0042029
Disease: Urinary tract infection
Urinary tract infection
0.070 Biomarker group BEFREE Carbapenem-Resistant KPC- and TEM-Producing <i>Escherichia coli</i> ST131 Isolated from a Hospitalized Patient with Urinary Tract Infection: First Isolation in Molise Region, Central Italy, July 2018. 31386590 2020
CUI: C0028754
Disease: Obesity
Obesity
0.070 GeneticVariation disease BEFREE Hence, these results suggest that TNMD genetic variants could be potentially useful as early life risk indicators for obesity and T2DM. 30850679 2019
CUI: C0042029
Disease: Urinary tract infection
Urinary tract infection
0.070 Biomarker group BEFREE One hundred and fifty-one <i>E. coli</i> isolates from bacteremia and UTI in children were screened for CTX-M, TEM, SHV and OXA β-lactamases by polymerase chain reaction and sequencing. 30013375 2018
CUI: C0042029
Disease: Urinary tract infection
Urinary tract infection
0.070 Biomarker group BEFREE The present study was aimed to detect the prevalence of TEM and CTX-M type genes from GNB on urinary tract infection (UTIs). 29778819 2018
CUI: C0042029
Disease: Urinary tract infection
Urinary tract infection
0.070 Biomarker group BEFREE Prevalence of TEM, SHV, and CTX-M genes of extended-spectrum β-lactamase-producing Escherichia coli strains isolated from urinary tract infections in adults. 28710743 2017
CUI: C0042029
Disease: Urinary tract infection
Urinary tract infection
0.070 Biomarker group BEFREE Pharmacodynamics of Finafloxacin, Ciprofloxacin, and Levofloxacin in Serum and Urine against TEM- and SHV-Type Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae Isolates from Patients with Urinary Tract Infections. 28193648 2017
CUI: C0028754
Disease: Obesity
Obesity
0.070 Biomarker disease BEFREE Our data suggest that TNMD acts as a protective factor in visceral adipose tissue to alleviate insulin resistance in obesity. 26880110 2016
CUI: C0042029
Disease: Urinary tract infection
Urinary tract infection
0.070 Biomarker group BEFREE We, therefore, determined the prevalence and co-resistance of PA and non-PA ESBL-E. coli in community-acquired and nosocomial urinary tract infections in humans and bla CTX-M-1 and bla TEM-52 isolates from poultry. 23519865 2013
CUI: C0028754
Disease: Obesity
Obesity
0.070 Biomarker disease BEFREE In this review, the potential mechanisms that could link TNMD with the pathogenesis of obesity and related disorders are discussed. 20429799 2010
CUI: C0028754
Disease: Obesity
Obesity
0.070 AlteredExpression disease BEFREE The aim of this study was to investigate TNMD tissue distribution and TNMD gene expression in human adipose tissue in relation to obesity and metabolic disease. 19602561 2009
CUI: C0028754
Disease: Obesity
Obesity
0.070 GeneticVariation disease BEFREE We have reported that the sequence variation in the tenomodulin (TNMD) gene is associated with the risk of type 2 diabetes (T2DM), central obesity and serum levels of systemic immune mediators in the Finnish Diabetes Prevention Study (DPS), which is a longitudinal lifestyle intervention study on 522 middle-aged persons with impaired glucose tolerance (IGT). 18982016 2008
CUI: C0028754
Disease: Obesity
Obesity
0.070 GeneticVariation disease BEFREE We have reported that the genetic variation of the tenomodulin gene (TNMD) is associated with the risk of type 2 diabetes (T2DM), central obesity, and impaired glucose metabolism and the TNMD mRNA levels correlate with serum and mRNA levels of inflammatory markers. 18580688 2008
CUI: C0028754
Disease: Obesity
Obesity
0.070 Biomarker disease BEFREE Tenomodulin is associated with obesity and diabetes risk: the Finnish diabetes prevention study. 17495183 2007
CUI: C0042029
Disease: Urinary tract infection
Urinary tract infection
0.070 Biomarker group BEFREE During a previous survey, five extended-spectrum beta-lactamase (ESBL)-producing enterobacteria (ESBLE) (two Enterobacter aerogenes isolates expressing TEM-24 b, two Escherichia coli isolates expressing TEM-21 or TEM-24 b, and one Klebsiella pneumoniae isolate expressing SHV-4/TEM-15) responsible for urinary tract infections (UTIs) were found among 1,584 strains collected from community patients. 16207960 2005
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 Biomarker group BEFREE We adopted three different methods: TEM, NTA and western blot analysis to characterize the cell-derived exosomes from NCI-H69 SCLC cell line and normal bronchial epithelial BEAS-2B cell line. we next explored the effects of these exosomes on HUVE cell proliferation and migration in vitro.To verify sFlt-1-loaded exosomes suppress the tumor growth in vivo,we established subcutaneous xenografts in nude mice using the NCI-H69 cell line. 31441580 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 Biomarker group BEFREE For this, we explored the tumor microenvironment for targeted drug delivery and synthesized (temperature and pH responsive) double triggered polymeric nanoparticles by the free radical mechanism and characterized them by DLS and TEM. 31549130 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 Biomarker group BEFREE The sequential delivery vesicles showed the anticipated three-layered TEM structure and dual-convertible (surface charge- and particle size-reversible) features in the tumor environment (pH 6.5), which guaranteed the sequential release of siVEGF-CPPs and PTX in the tumor extracellular environment and tumor cells, respectively. 30144476 2018
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 Biomarker group BEFREE Interestingly, TEM images of tumor sections show intercellular lysosomal subcellular localization of the GNP-ABPs. 30148621 2018
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 Biomarker group BEFREE Our recent work has shown that breast cancer cell adhesion to vascular endothelial cells activates endothelial MMP-2, promoting tumor cell transendothelial migration (TEM(E)). 20571065 2010
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.060 Biomarker group BEFREE Furthermore, the transduction of either Ad-shTeM or Ad-shChM-I in human melanoma cells resulted in suppression of tumor growth in association with decreased vessel density in vivo. 15150318 2004
CUI: C0276640
Disease: Transmissible mink encephalopathy
Transmissible mink encephalopathy
0.050 Biomarker disease BEFREE The surface morphology, crystal structure, functional groups, elemental composition, and optical properties of the Si-CQDs were characterized using TEM (HRTEM), XRD, FT-IR, XPS, UV-vis absorption and fluorescence spectroscopy. 31280375 2019
CUI: C0276640
Disease: Transmissible mink encephalopathy
Transmissible mink encephalopathy
0.050 Biomarker disease BEFREE Using 30keV, which is lower than that for conventional TEM (100-300keV), together with low detection angles (15-55mrad) enhances the signals from the fibrils. 28267641 2017
CUI: C0276640
Disease: Transmissible mink encephalopathy
Transmissible mink encephalopathy
0.050 Biomarker disease BEFREE The structure, morphology, and optical properties of the as-prepared WS<sub>2</sub>/Bi<sub>2</sub>MoO<sub>6</sub> samples were characterized by XRD, XPS, SEM, TEM (HRTEM), and UV-vis diffuse reflectance spectra (DRS). 28565885 2017
CUI: C0276640
Disease: Transmissible mink encephalopathy
Transmissible mink encephalopathy
0.050 Biomarker disease BEFREE Isolates were screened for the presence of the β-lactamase-TEM (BlaTEM) and β-lactamase-cfxA genes using Polymerase Chain Reaction (PCR). 27119762 2016
CUI: C0276640
Disease: Transmissible mink encephalopathy
Transmissible mink encephalopathy
0.050 GeneticVariation disease BEFREE Three isolates harbored both bla(TEM-34(IRT-6)) and bla(CTX-M-15). bla(SHV-12) was identified either alone or with bla(CTX-M-15) in a single isolate. 21288137 2011