Cerebrovascular accident
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.
|
24262325 |
2014 |
CORONARY ARTERY DISEASE, AUTOSOMAL DOMINANT, 1
|
|
0.700 |
GeneticVariation
|
GWASDB |
Large-scale association analysis identifies new risk loci for coronary artery disease.
|
23202125 |
2013 |
Atherosclerosis
|
|
0.030 |
GeneticVariation
|
BEFREE |
In the present study, we aimed to examine the role of two single-nucleotide polymorphisms (SNPs), rs3825807 and rs11556924, located in the ADAMTS7 and ZC3HC1 genes, respectively, associated with CAD in published GWASs in European populations and their possible contribution to the development of coronary atherosclerosis and cerebral LA atherosclerosis in a case-control study of an the Iranian population.
|
31679296 |
2019 |
Arteriosclerosis
|
|
0.030 |
GeneticVariation
|
BEFREE |
In the present study, we aimed to examine the role of two single-nucleotide polymorphisms (SNPs), rs3825807 and rs11556924, located in the ADAMTS7 and ZC3HC1 genes, respectively, associated with CAD in published GWASs in European populations and their possible contribution to the development of coronary atherosclerosis and cerebral LA atherosclerosis in a case-control study of an the Iranian population.
|
31679296 |
2019 |
Arteriosclerosis
|
|
0.030 |
GeneticVariation
|
BEFREE |
The resulting amino acid change Arg363His is associated with increased expression and nuclear mobility, as well as lower rates of cell growth in HeLa cells, further supporting a role for cell proliferation in atherosclerosis and its clinical consequences.
|
28115489 |
2017 |
Atherosclerosis
|
|
0.030 |
GeneticVariation
|
BEFREE |
The resulting amino acid change Arg363His is associated with increased expression and nuclear mobility, as well as lower rates of cell growth in HeLa cells, further supporting a role for cell proliferation in atherosclerosis and its clinical consequences.
|
28115489 |
2017 |
Arteriosclerosis
|
|
0.030 |
GeneticVariation
|
BEFREE |
Our results indicate that ZC3HC1 rs11556924 polymorphism is associated with subclinical atherosclerosis in RA.
|
24286297 |
2013 |
Atherosclerosis
|
|
0.030 |
GeneticVariation
|
BEFREE |
Our results indicate that ZC3HC1 rs11556924 polymorphism is associated with subclinical atherosclerosis in RA.
|
24286297 |
2013 |
Ischemic stroke
|
|
0.010 |
GeneticVariation
|
BEFREE |
Regarding ZC3HC1 rs11556924, our study further supports the observed association of rs11556924 with LA IS coming from previous GWASs.
|
31679296 |
2019 |
Coronary Arteriosclerosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
These findings extend the genetic association between rs11556924 and coronary artery disease risk by characterizing its effects on the encoded protein, NIPA.
|
28115489 |
2017 |
Hypertensive disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
A subpopulation that had available follow-up data from ages of 40, 45, and 50 years was also analyzed.ZC3HC1 rs11556924 (C > T) genotype CC was associated with hypertension compared with the T-allele carriers (P = 0.013).
|
26266351 |
2015 |
Essential Hypertension
|
|
0.010 |
GeneticVariation
|
BEFREE |
Its major TT-genotype was associated with higher total cholesterol (P = 0.044) and LDL (P = 0.029) compared with the C-allele.We report for the first time that ZC3HC1 rs11556924 was associated with essential hypertension in 50-year-old patients.
|
26266351 |
2015 |
Rheumatoid Arthritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our results indicate that ZC3HC1 rs11556924 polymorphism is associated with subclinical atherosclerosis in RA.
|
24286297 |
2013 |