|
Malignant Neoplasms
|
|
0.020 |
GeneticVariation
|
BEFREE |
Our results suggest that rs3761548 polymorphism is associated with cancer risk.
|
30142808 |
2018 |
|
Autoimmune Diseases
|
|
0.020 |
GeneticVariation
|
BEFREE |
FoxP3 rs3761548 polymorphism predicts autoimmune disease susceptibility: a meta-analysis.
|
23993983 |
2013 |
|
VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding)
|
|
0.020 |
GeneticVariation
|
BEFREE |
The rs3761548 of FOXP3 gene in our population may be associated with susceptibility to vitiligo because of altered expression.
|
23498308 |
2013 |
|
Primary malignant neoplasm
|
|
0.020 |
GeneticVariation
|
BEFREE |
Our results suggest that rs3761548 polymorphism is associated with cancer risk.
|
30142808 |
2018 |
|
VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding)
|
|
0.020 |
GeneticVariation
|
BEFREE |
Significantly increased vitiligo risk was associated with the rs2232365 GG [odds ratio (OR) 1·68, 95% confidence interval (CI) 1·17-2·39, P = 0·004] and rs3761548 AA (OR 1·82, 95% CI 1·10-3·01, P = 0·033) genotypes compared with the rs2232365 AA and rs3761548 CC genotypes.
|
23582052 |
2013 |
|
Acute Chest Syndrome
|
|
0.020 |
GeneticVariation
|
BEFREE |
In the present study, we analysed the expression of FOXP3 as well as the association between two variants in this gene (rs3761548A/C and rs5902434del/ATT) and occurrence of ACS in Iranian patients.
|
26931655 |
2016 |
|
Neoplasms
|
|
0.020 |
GeneticVariation
|
BEFREE |
However, with respect to AA genotype of rs3761548, we found highly significant association with the advanced stage (T3-4) of the tumor (OR = 3.90; 95% confidence interval (CI) = 1.56-9.70; p = 0.03).
|
24338714 |
2014 |
|
Tumor Progression
|
|
0.020 |
GeneticVariation
|
BEFREE |
Our study suggests that <i>FOXP3</i> polymorphism rs3761548 is associated with BC susceptibility in the Chinese and may be involved in tumor progression.
|
29731666 |
2018 |
|
Autoimmune Diseases
|
|
0.020 |
GeneticVariation
|
BEFREE |
The rs3761548 polymorphism (-3279 C>A) of FOXP3 gene is associated with several autoimmune disorders.
|
23498308 |
2013 |
|
Hepatic Veno-Occlusive Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
In conclusion, this is the first report on FOXP3 rs3761548 SNP in allo-HSCT and we suggest that this SNP be considered a candidate marker for predicting the development of HVOD and CMV infection after allo-HSCT.
|
26735609 |
2016 |
|
Psoriasis
|
|
0.010 |
GeneticVariation
|
BEFREE |
However, IL-10 (rs1800896) and FOXP3 (rs3761548) gene polymorphisms were not associated with psoriasis risk.
|
28027921 |
2017 |
|
Pemphigus Foliaceus
|
|
0.010 |
GeneticVariation
|
BEFREE |
In the whole population, rs3761548, rs3761549 and rs2294021 were associated with the susceptibility to PF.
|
28216259 |
2017 |
|
Degenerative polyarthritis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our findings indicated that the association between FOXP3 rs2232365 polymorphism and knee OA tended to yield negative results but the FOXP3 rs3761548 C allele was associated with elevated risk of OA in Grade 4 knee OA patients in a Turkish population.
|
30168273 |
2018 |
|
Colorectal Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Moreover, the A allele of rs3761548 was observed to be associated with higher susceptibility of CRC [OR (95% CI) = 1.792 (1.424-2.254)].
|
25416053 |
2014 |
|
Autoimmune thyroid disease (AITD)
|
|
0.010 |
GeneticVariation
|
BEFREE |
There was no allelic association of rs3761548 and rs3761549 polymorphisms with AITD susceptibility, albeit a significant difference in genotype distribution with respect to rs3761549.
|
30771152 |
2019 |
|
Cytomegalovirus Infections
|
|
0.010 |
GeneticVariation
|
BEFREE |
In conclusion, this is the first report on FOXP3 rs3761548 SNP in allo-HSCT and we suggest that this SNP be considered a candidate marker for predicting the development of HVOD and CMV infection after allo-HSCT.
|
26735609 |
2016 |
|
Endometriosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
No associations were found with rs3761548 and rs2232366 either for endometriosis-related infertility group or idiopathic infertility group.
|
21481380 |
2011 |
|
Crohn Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
The variant allele of rs3761548 was increased in male patients with penetrating CD compared to those with non-stricturing, non-penetrating CD.
|
30710380 |
2019 |
|
Non-Small Cell Lung Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The data showed that the A allele of rs3761548 significantly increased NSCLC risk (P=0.000, OR=2.32, 95%CI=1.736-3.102).
|
24035934 |
2013 |
|
Osteoarthritis, Knee
|
|
0.010 |
GeneticVariation
|
BEFREE |
FOXP3 rs3761548 polymorphism is associated with knee osteoarthritis in a Turkish population.
|
30168273 |
2018 |
|
Prostate carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Evaluation of the genetic variations in position SNP rs3761548</span> revealed that the AA genotype and A allele were more prevalent whereas CC genotype and C allele were less prevalent in PC patients when compared with healthy men (P < 0.01, P < 0.001, P < 0.002 and P < 0.001, respectively).
|
30057362 |
2019 |
|
Systemic Scleroderma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Single-marker analysis of allelic and genotype frequencies revealed that SNP rs3761548 was not associated with systemic sclerosis susceptibility.
|
23707908 |
2013 |
|
Triple-Negative Breast Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
This study aimed to investigate a polymorphism (rs3761548) and the protein expression of FOXP3 for a possible involvement in TNBC susceptibility and prognosis.
|
24877082 |
2014 |
|
Kidney Failure, Chronic
|
|
0.010 |
GeneticVariation
|
BEFREE |
We observed significantly higher occurrence of mutant genotypes of tag-SNPs of FOXP3 namely; rs2232365 and rs3761548 along with NF-kB1 namely; rs28362491 and rs696 in ESRD and ARE cases, suggested a risk association for ESRD and ARE.
|
26794449 |
2016 |
|
Hashimoto Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
Haplotype analysis revealed an increased frequency of rs3761548 "C"-rs3761549 "T" in HT and GD subjects, thereby associating it with disease predisposition (p = 0.03).
|
30771152 |
2019 |