Source: RGD

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885 44
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885 44
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808 21
EP300 Q09472 E1A binding protein p300 1.00 0.459 0.846 20
GRIN2B Q13224 glutamate ionotropic receptor NMDA type subunit 2B Ion channel 1.00 0.510 0.692 19
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885 18
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923 18
PRKCB P05771 protein kinase C beta Kinase 1.00 0.453 0.885 15
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808 14
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808 12
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885 11
TEK Q02763 TEK receptor tyrosine kinase Kinase 1.00 0.462 0.692 11
TJP1 Q07157 tight junction protein 1 Cell-cell junction 1.00 0.576 0.692 11
MAP2 P11137 microtubule associated protein 2 1.00 0.537 0.692 9
ADAM10 O14672 ADAM metallopeptidase domain 10 1.00 0.489 0.846 8
COL3A1 P02461 collagen type III alpha 1 chain 1.00 0.477 0.808 8
DMD P11532 dystrophin 1.00 0.423 0.923 8
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846 8
ACAN P16112 aggrecan Extracellular structure 1.00 0.528 0.846 7
ITPR1 Q14643 inositol 1,4,5-trisphosphate receptor type 1 Ion channel 1.00 0.534 0.846 7
HDAC5 Q9UQL6 histone deacetylase 5 Epigenetic regulator 1.00 0.552 0.769 7
COL1A2 P08123 collagen type I alpha 2 chain 1.00 0.486 0.846 6
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846 6
HDAC4 P56524 histone deacetylase 4 Epigenetic regulator 1.00 0.484 0.885 6