Source: CTD_human

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
IL6 P05231 interleukin 6 0.32 0.248 0.962 262
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962 224
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 182
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885 178
IFNG P01579 interferon gamma 0.47 0.288 0.962 157
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923 135
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962 111
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885 107
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885 105
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923 98
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885 96
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923 92
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885 80
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962 77
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962 76
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962 76
IL2 P60568 interleukin 2 0.48 0.336 0.885 73
NPPA P01160 natriuretic peptide A 5.5E-04 0.505 0.769 61
CYP2E1 P05181 cytochrome P450 family 2 subfamily E member 1 8.1E-09 0.459 0.885 60
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923 59
EPHX1 P07099 epoxide hydrolase 1 3.2E-09 0.500 0.846 57
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923 57
APOA1 P02647 apolipoprotein A1 5.5E-04 0.429 0.885 53
GSTT1 P30711 glutathione S-transferase theta 1 1.5E-04 0.393 0.923 48