Source: CURATED

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
PDPK1 O15530 3-phosphoinositide dependent protein kinase 1 Kinase 0.98 0.588 0.808 14 0
MTR Q99707 5-methyltetrahydrofolate-homocysteine methyltransferase 2.4E-12 0.482 0.808 38 9
AKAP12 Q02952 A-kinase anchoring protein 12 3.6E-02 0.566 0.615 6 7
ARAF P10398 A-Raf proto-oncogene, serine/threonine kinase Kinase 0.96 0.619 0.654 7 2
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923 37 28
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885 100 3
ACTA2 P62736 actin alpha 2, smooth muscle Cellular structure 0.93 0.508 0.846 40 21
ACVR1 Q04771 activin A receptor type 1 Kinase 0.33 0.535 0.731 28 10
ADAM10 O14672 ADAM metallopeptidase domain 10 1.00 0.489 0.846 17 21
ADAM33 Q9BZ11 ADAM metallopeptidase domain 33 Enzyme 2.1E-15 0.636 0.423 7 1
ADAMTS1 Q9UHI8 ADAM metallopeptidase with thrombospondin type 1 motif 1 Enzyme 0.72 0.555 0.654 15 1
APRT P07741 adenine phosphoribosyltransferase 5.5E-13 0.423 0.846 21 11
ADAR P55265 adenosine deaminase RNA specific Enzyme 2.6E-02 0.501 0.808 14 27
ARF1 P84077 ADP ribosylation factor 1 0.90 0.626 0.615 8 4
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962 109 7
AKT2 P31751 AKT serine/threonine kinase 2 Kinase 0.64 0.474 0.769 27 10
ALDOA P04075 aldolase, fructose-bisphosphate A 1.3E-03 0.631 0.615 12 4
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846 45 30
ALKBH8 Q96BT7 alkB homolog 8, tRNA methyltransferase 2.0E-04 0.716 0.423 10 1
AFP P02771 alpha fetoprotein Transporter 1.1E-11 0.429 0.885 19 3
AREG P15514 amphiregulin Signaling 0.35 0.487 0.769 32 0
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846 63 137
ANGPTL4 Q9BY76 angiopoietin like 4 Signaling 2.3E-11 0.498 0.731 21 5
ANKRD34A Q69YU3 ankyrin repeat domain 34A 0.98 0.861 0.077 5 0