Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923 33 42
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923 11 10
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885 94 101
HLA-DQB1 P01920 major histocompatibility complex, class II, DQ beta 1 Immune response 8.9E-03 0.407 0.885 33 30
NRG1 Q02297 neuregulin 1 Signaling 1.00 0.464 0.885 28 23
NCAM1 P13591 neural cell adhesion molecule 1 1.00 0.415 0.885 13 25
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885 12 4
F2 P00734 coagulation factor II, thrombin Enzyme 1.1E-03 0.415 0.885 10 7
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885 6 4
HLA-DRB3 P79483 major histocompatibility complex, class II, DR beta 3 Immune response 0.570 0.885 5 21
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885 4 5
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885 4 3
SLCO6A1 Q86UG4 solute carrier organic anion transporter family member 6A1 Transporter 2.9E-11 0.412 0.885 2 2
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885 2 2
ERCC8 Q13216 ERCC excision repair 8, CSA ubiquitin ligase complex subunit 2.8E-15 0.551 0.885 1 1
TCF7L2 Q9NQB0 transcription factor 7 like 2 1.00 0.485 0.846 50 31
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846 48 44
HLA-DQA1 P01909 major histocompatibility complex, class II, DQ alpha 1 Immune response 2.4E-02 0.416 0.846 37 36
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846 30 9
RERE Q9P2R6 arginine-glutamic acid dipeptide repeats 1.00 0.526 0.846 29 32
FHIT P49789 fragile histidine triad diadenosine triphosphatase 5.7E-03 0.444 0.846 23 24
CDH13 P55290 cadherin 13 7.1E-04 0.501 0.846 20 29
TCF4 P15884 transcription factor 4 Transcription factor 1.00 0.464 0.846 18 36
NT5C2 P49902 5'-nucleotidase, cytosolic II Enzyme 2.1E-06 0.537 0.846 16 13