Source: GWASCAT

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases Num. SNPs
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846 14 14
SYNE1 Q8NF91 spectrin repeat containing nuclear envelope protein 1 3.2E-52 0.511 0.846 12 17
PRKD1 Q15139 protein kinase D1 Kinase 6.6E-07 0.531 0.846 11 15
DPYD Q12882 dihydropyrimidine dehydrogenase Enzyme 3.4E-22 0.493 0.846 9 20
ADAM10 O14672 ADAM metallopeptidase domain 10 1.00 0.489 0.846 3 3
FOXP1 Q9H334 forkhead box P1 1.00 0.460 0.808 33 33
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808 26 30
HCP5 Q6MZN7 HLA complex P5 0.595 0.808 23 17
FOXO3 O43524 forkhead box O3 0.99 0.431 0.808 17 21
EHMT2 Q96KQ7 euchromatic histone lysine methyltransferase 2 Epigenetic regulator 1.0E-04 0.590 0.808 16 9
DCC P43146 DCC netrin 1 receptor 0.99 0.471 0.808 16 59
FOXP2 O15409 forkhead box P2 1.00 0.545 0.808 13 12
DDR1 Q08345 discoidin domain receptor tyrosine kinase 1 Kinase 4.6E-06 0.497 0.808 9 5
ZEB2 O60315 zinc finger E-box binding homeobox 2 Transcription factor 1.00 0.471 0.808 9 8
AKT3 Q9Y243 AKT serine/threonine kinase 3 Kinase 1.00 0.512 0.808 8 13
ASAP1 Q9ULH1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 1.00 0.556 0.808 6 6
ALMS1 Q8TCU4 ALMS1 centrosome and basal body associated protein 4.5E-60 0.559 0.808 6 11
RAP1A P62834 RAP1A, member of RAS oncogene family Enzyme modulator 0.62 0.502 0.808 5 5
TBX1 O43435 T-box transcription factor 1 Transcription factor 0.84 0.433 0.808 5 3
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808 4 4
ATP2A2 P16615 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 Transporter 1.00 0.529 0.808 4 3
PSMB9 P28065 proteasome 20S subunit beta 9 2.7E-03 0.514 0.808 4 3
MDK P21741 midkine Signaling 0.23 0.494 0.808 2 1
RASSF1 Q9NS23 Ras association domain family member 1 Enzyme modulator 4.9E-06 0.420 0.808 1 2