Source: ANIMAL_MODELS

Gene Uniprot Gene Full Name Protein Class pLI DSI g DPI g Num. diseases
SYP P08247 synaptophysin Transporter 0.92 0.481 0.808 1
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962 23
SERPINF1 P36955 serpin family F member 1 Enzyme modulator 7.8E-08 0.460 0.846 20
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923 23
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962 76
PTGS1 P23219 prostaglandin-endoperoxide synthase 1 Enzyme 6.2E-07 0.460 0.885 19
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846 4
PPARGC1A Q9UBK2 PPARG coactivator 1 alpha Transcription factor 1.00 0.453 0.885 42
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923 34
PLCB1 Q9NQ66 phospholipase C beta 1 Enzyme 0.98 0.595 0.654 3
PIN1 Q13526 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.74 0.488 0.769 5
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885 23
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923 60
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808 14
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846 22
NGB Q9NPG2 neuroglobin Transporter 4.5E-03 0.631 0.462 6
NGFR P08138 nerve growth factor receptor Receptor 9.8E-02 0.477 0.846 23
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885 24
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923 5
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846 38
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923 16
MAP2 P11137 microtubule associated protein 2 1.00 0.537 0.692 9
MT2A P02795 metallothionein 2A 1.2E-05 0.553 0.808 9
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808 12